Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram
The integration of physiological (PET) and anatomical (CT) images in cancer delineation requires an accurate spatial registration technique. Although hybrid PET/CT scanner is used to co-register these images, significant misregistrations exist due to patient and respiratory/cardiac motions. This pap...
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| Format: | Article |
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Elsevier
2015
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| _version_ | 1796860189173874688 |
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| author | Mokri, Siti Salasiah Saripan, M. I. Marhaban, Mohammad Hamiruce Nordin, Abdul Jalil Hashim, Suhairul |
| author_facet | Mokri, Siti Salasiah Saripan, M. I. Marhaban, Mohammad Hamiruce Nordin, Abdul Jalil Hashim, Suhairul |
| author_sort | Mokri, Siti Salasiah |
| collection | ePrints |
| description | The integration of physiological (PET) and anatomical (CT) images in cancer delineation requires an accurate spatial registration technique. Although hybrid PET/CT scanner is used to co-register these images, significant misregistrations exist due to patient and respiratory/cardiac motions. This paper proposes a hybrid feature-intensity based registration technique for hybrid PET/CT scanner. First, simulated PET sinogram was filtered with a 3D hybrid mean-median before reconstructing the image. The features were then derived from the segmented structures (lung, heart and tumor) from both images. The registration was performed based on modified multi-modality demon registration with multiresolution scheme. Apart from visual observations improvements, the proposed registration technique increased the normalized mutual information index (NMI) between the PET/CT images after registration. All nine tested datasets show marked improvements in mutual information (MI) index than free form deformation (FFD) registration technique with the highest MI increase is 25% |
| first_indexed | 2024-03-05T19:38:13Z |
| format | Article |
| id | utm.eprints-55624 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T19:38:13Z |
| publishDate | 2015 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | utm.eprints-556242017-02-15T03:30:57Z http://eprints.utm.my/55624/ Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram Mokri, Siti Salasiah Saripan, M. I. Marhaban, Mohammad Hamiruce Nordin, Abdul Jalil Hashim, Suhairul QC Physics The integration of physiological (PET) and anatomical (CT) images in cancer delineation requires an accurate spatial registration technique. Although hybrid PET/CT scanner is used to co-register these images, significant misregistrations exist due to patient and respiratory/cardiac motions. This paper proposes a hybrid feature-intensity based registration technique for hybrid PET/CT scanner. First, simulated PET sinogram was filtered with a 3D hybrid mean-median before reconstructing the image. The features were then derived from the segmented structures (lung, heart and tumor) from both images. The registration was performed based on modified multi-modality demon registration with multiresolution scheme. Apart from visual observations improvements, the proposed registration technique increased the normalized mutual information index (NMI) between the PET/CT images after registration. All nine tested datasets show marked improvements in mutual information (MI) index than free form deformation (FFD) registration technique with the highest MI increase is 25% Elsevier 2015-11 Article PeerReviewed Mokri, Siti Salasiah and Saripan, M. I. and Marhaban, Mohammad Hamiruce and Nordin, Abdul Jalil and Hashim, Suhairul (2015) Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram. Radiation Physics and Chemistry, 116 . pp. 300-304. ISSN 0969-806X http://dx.doi.org/10.1016/j.radphyschem.2015.01.022 DOI:10.1016/j.radphyschem.2015.01.022 |
| spellingShingle | QC Physics Mokri, Siti Salasiah Saripan, M. I. Marhaban, Mohammad Hamiruce Nordin, Abdul Jalil Hashim, Suhairul Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram |
| title | Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram |
| title_full | Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram |
| title_fullStr | Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram |
| title_full_unstemmed | Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram |
| title_short | Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram |
| title_sort | hybrid registration of pet ct in thoracic region with pre filtering pet sinogram |
| topic | QC Physics |
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