Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method
Poly(vinylidene fluoride) (PVDF) scaffolds were prepared via electrospinning. The response surface methodology (RSM) was used to optimize the parameters that influence the average fibre diameter. The objective is to produce fibres with small diameters. The factors considered for experimental design...
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| Format: | Article |
| Language: | English |
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Penerbit UTM Press
2015
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| Online Access: | http://eprints.utm.my/56195/1/MohamedMahmoud2015_OptimizationofElecrospinningofPVDFScaffolds.pdf |
| _version_ | 1796860341364195328 |
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| author | Nallappan, Madana Leela Nasef, Mohamad Mahmoud |
| author_facet | Nallappan, Madana Leela Nasef, Mohamad Mahmoud |
| author_sort | Nallappan, Madana Leela |
| collection | ePrints |
| description | Poly(vinylidene fluoride) (PVDF) scaffolds were prepared via electrospinning. The response surface methodology (RSM) was used to optimize the parameters that influence the average fibre diameter. The objective is to produce fibres with small diameters. The factors considered for experimental design were the applied electric voltage, the PVDF solution concentration, and the distance between the needle tip and the collecting drum. The Central Composite Design (CCD) was used to generate the experimental design whilst the analysis of variance (ANOVA) was performed to obtain statistical validation of regression models and to study the interaction between input parameters. The optimum operating conditions that guaranteed PVDF scaffolds with small nanofibre diameter were in the voltage and concentration range of 16-20 kV and 10-14wt%. |
| first_indexed | 2024-03-05T19:39:55Z |
| format | Article |
| id | utm.eprints-56195 |
| institution | Universiti Teknologi Malaysia - ePrints |
| language | English |
| last_indexed | 2024-03-05T19:39:55Z |
| publishDate | 2015 |
| publisher | Penerbit UTM Press |
| record_format | dspace |
| spelling | utm.eprints-561952017-11-01T04:16:56Z http://eprints.utm.my/56195/ Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method Nallappan, Madana Leela Nasef, Mohamad Mahmoud TP Chemical technology Poly(vinylidene fluoride) (PVDF) scaffolds were prepared via electrospinning. The response surface methodology (RSM) was used to optimize the parameters that influence the average fibre diameter. The objective is to produce fibres with small diameters. The factors considered for experimental design were the applied electric voltage, the PVDF solution concentration, and the distance between the needle tip and the collecting drum. The Central Composite Design (CCD) was used to generate the experimental design whilst the analysis of variance (ANOVA) was performed to obtain statistical validation of regression models and to study the interaction between input parameters. The optimum operating conditions that guaranteed PVDF scaffolds with small nanofibre diameter were in the voltage and concentration range of 16-20 kV and 10-14wt%. Penerbit UTM Press 2015-01 Article PeerReviewed application/pdf en http://eprints.utm.my/56195/1/MohamedMahmoud2015_OptimizationofElecrospinningofPVDFScaffolds.pdf Nallappan, Madana Leela and Nasef, Mohamad Mahmoud (2015) Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method. Jurnal Teknologi, 75 (6). pp. 103-107. ISSN 2180-3722 http://dx.doi.org/10.11113/jt.v75.5193 DOI:10.11113/jt.v75.5193 |
| spellingShingle | TP Chemical technology Nallappan, Madana Leela Nasef, Mohamad Mahmoud Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method |
| title | Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method |
| title_full | Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method |
| title_fullStr | Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method |
| title_full_unstemmed | Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method |
| title_short | Optimization of elecrospinning of PVDF scaffolds fabrication using response surface method |
| title_sort | optimization of elecrospinning of pvdf scaffolds fabrication using response surface method |
| topic | TP Chemical technology |
| url | http://eprints.utm.my/56195/1/MohamedMahmoud2015_OptimizationofElecrospinningofPVDFScaffolds.pdf |
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