Combination of Er:YAG laser and CO2 laser treatment on skin Tissue
Skin is the most important organ in our body, as it protects us from external environmental effects. Study the ability of the skin to stretch and the histological examinations of irradiated tissues have significant values in scientific and medical applications. Only a few studies have been done to s...
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Blackwell Publishing Inc.
2015
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| author | Anayb Baleg, Sana Mohammed Bidin, Noriah Lau, Pik Suan Sidi Ahmad, Muhammad Fakarruddin Krishnan, Ganesan Johari, Abd. Rahman Hamid, Asmah |
| author_facet | Anayb Baleg, Sana Mohammed Bidin, Noriah Lau, Pik Suan Sidi Ahmad, Muhammad Fakarruddin Krishnan, Ganesan Johari, Abd. Rahman Hamid, Asmah |
| author_sort | Anayb Baleg, Sana Mohammed |
| collection | ePrints |
| description | Skin is the most important organ in our body, as it protects us from external environmental effects. Study the ability of the skin to stretch and the histological examinations of irradiated tissues have significant values in scientific and medical applications. Only a few studies have been done to study the correlation between epidermis ablation and the changes that occur at dermal levels when using dual lasers in ablative resurfacing mode. The aim of this work is to determine this correlation and to estimate the effects of multiple pulses on induced collagen remodeling and the strength of skin exposed with dual lasers in an in vivo rat model. All laser exposures led to mark improvement in the skin's strength compared to their own controls. The histological investigation indicated that there was a thickness loss in the epidermis layer with the induction of deep collagen coagulation in the dermis layer as the dual laser pulses increased. Additionally, more collagen fibers were remolded in the treated samples by dual wavelengths. We conclude that by combining dual lasers with multiple pulses targeted at not only the epidermis layer of the skin, it could also induce some heat diffusion in the dermis layer which causes more coagulation of collagen fibers. The tensile results confirmed by our histological data demonstrate that the strength of irradiated skin with dual wavelengths increased more than using both lasers separately on the skin tissue since more collagen is induced. The skin is an important body-organ, protecting us from external environmental effects. Studies concerning the ability of skin to stretch and histological examinations of irradiated tissues have significant values for scientific and medical applications. Only few studies have been done to study the correlation between epidermis ablation and the changes that occur at dermal levels when using dual lasers in ablative resurfacing mode. The aim of this work is to determine this correlation and to estimate the effects of multiple pulses on induced collagen remodeling and the strength of skin exposed to dual lasers in an in vivo rat model. |
| first_indexed | 2024-03-05T19:41:21Z |
| format | Article |
| id | utm.eprints-58078 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T19:41:21Z |
| publishDate | 2015 |
| publisher | Blackwell Publishing Inc. |
| record_format | dspace |
| spelling | utm.eprints-580782021-12-07T02:50:38Z http://eprints.utm.my/58078/ Combination of Er:YAG laser and CO2 laser treatment on skin Tissue Anayb Baleg, Sana Mohammed Bidin, Noriah Lau, Pik Suan Sidi Ahmad, Muhammad Fakarruddin Krishnan, Ganesan Johari, Abd. Rahman Hamid, Asmah QC Physics Skin is the most important organ in our body, as it protects us from external environmental effects. Study the ability of the skin to stretch and the histological examinations of irradiated tissues have significant values in scientific and medical applications. Only a few studies have been done to study the correlation between epidermis ablation and the changes that occur at dermal levels when using dual lasers in ablative resurfacing mode. The aim of this work is to determine this correlation and to estimate the effects of multiple pulses on induced collagen remodeling and the strength of skin exposed with dual lasers in an in vivo rat model. All laser exposures led to mark improvement in the skin's strength compared to their own controls. The histological investigation indicated that there was a thickness loss in the epidermis layer with the induction of deep collagen coagulation in the dermis layer as the dual laser pulses increased. Additionally, more collagen fibers were remolded in the treated samples by dual wavelengths. We conclude that by combining dual lasers with multiple pulses targeted at not only the epidermis layer of the skin, it could also induce some heat diffusion in the dermis layer which causes more coagulation of collagen fibers. The tensile results confirmed by our histological data demonstrate that the strength of irradiated skin with dual wavelengths increased more than using both lasers separately on the skin tissue since more collagen is induced. The skin is an important body-organ, protecting us from external environmental effects. Studies concerning the ability of skin to stretch and histological examinations of irradiated tissues have significant values for scientific and medical applications. Only few studies have been done to study the correlation between epidermis ablation and the changes that occur at dermal levels when using dual lasers in ablative resurfacing mode. The aim of this work is to determine this correlation and to estimate the effects of multiple pulses on induced collagen remodeling and the strength of skin exposed to dual lasers in an in vivo rat model. Blackwell Publishing Inc. 2015 Article PeerReviewed Anayb Baleg, Sana Mohammed and Bidin, Noriah and Lau, Pik Suan and Sidi Ahmad, Muhammad Fakarruddin and Krishnan, Ganesan and Johari, Abd. Rahman and Hamid, Asmah (2015) Combination of Er:YAG laser and CO2 laser treatment on skin Tissue. Photochemistry and Photobiology, 91 (1). pp. 134-138. ISSN 0031-8655 http://dx.doi.org/10.1111/php.12369 DOI:10.1111/php.12369 |
| spellingShingle | QC Physics Anayb Baleg, Sana Mohammed Bidin, Noriah Lau, Pik Suan Sidi Ahmad, Muhammad Fakarruddin Krishnan, Ganesan Johari, Abd. Rahman Hamid, Asmah Combination of Er:YAG laser and CO2 laser treatment on skin Tissue |
| title | Combination of Er:YAG laser and CO2 laser treatment on skin Tissue |
| title_full | Combination of Er:YAG laser and CO2 laser treatment on skin Tissue |
| title_fullStr | Combination of Er:YAG laser and CO2 laser treatment on skin Tissue |
| title_full_unstemmed | Combination of Er:YAG laser and CO2 laser treatment on skin Tissue |
| title_short | Combination of Er:YAG laser and CO2 laser treatment on skin Tissue |
| title_sort | combination of er yag laser and co2 laser treatment on skin tissue |
| topic | QC Physics |
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