Continuous microwave flow synthesis of mesoporous hydroxyapatite
We have successfully used continuous microwave flow synthesis (CMFS) technique for the template free synthesis of mesoporous hydroxyapatite. The continuous microwave flow reactor consisted of a modified 2.45 GHz household microwave, peristaltic pumps and a Teflon coil. This cost effective and effici...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Published: |
Elsevier Ltd.
2015
|
| Subjects: |
| _version_ | 1796860453151834112 |
|---|---|
| author | Akram, Muhammad Alshemary, Ammar Z. Goh, Yi Fan Wan Ibrahim, Wan Aini Lintang, Hendrik Oktendy Hussain, Rafaqat |
| author_facet | Akram, Muhammad Alshemary, Ammar Z. Goh, Yi Fan Wan Ibrahim, Wan Aini Lintang, Hendrik Oktendy Hussain, Rafaqat |
| author_sort | Akram, Muhammad |
| collection | ePrints |
| description | We have successfully used continuous microwave flow synthesis (CMFS) technique for the template free synthesis of mesoporous hydroxyapatite. The continuous microwave flow reactor consisted of a modified 2.45 GHz household microwave, peristaltic pumps and a Teflon coil. This cost effective and efficient system was exploited to produce semi-crystalline phase pure nano-sized hydroxyapatite. Effect of microwave power, retention time and the concentration of reactants on the phase purity, degree of crystallinity and surface area of the final product was studied in detail. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) were used to study the phase purity and composition of the product, while transmission electron microscopy (TEM) was used to study the effect of process parameters on the morphology of hydroxyapatite. The TEM analysis confirmed the formation of spherical particles at low microwave power; however the morphology of the particles changed to mesoporous needle and rod-like structure upon exposing the reaction mixture to higher microwave power and longer retention time inside the microwave. The in-vitro ion dissolution behavior of the as synthesized hydroxyapatite was studied by determining the amount of Ca2+ ion released in SBF solution. |
| first_indexed | 2024-03-05T19:41:35Z |
| format | Article |
| id | utm.eprints-58158 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T19:41:35Z |
| publishDate | 2015 |
| publisher | Elsevier Ltd. |
| record_format | dspace |
| spelling | utm.eprints-581582021-08-30T09:30:10Z http://eprints.utm.my/58158/ Continuous microwave flow synthesis of mesoporous hydroxyapatite Akram, Muhammad Alshemary, Ammar Z. Goh, Yi Fan Wan Ibrahim, Wan Aini Lintang, Hendrik Oktendy Hussain, Rafaqat QD Chemistry We have successfully used continuous microwave flow synthesis (CMFS) technique for the template free synthesis of mesoporous hydroxyapatite. The continuous microwave flow reactor consisted of a modified 2.45 GHz household microwave, peristaltic pumps and a Teflon coil. This cost effective and efficient system was exploited to produce semi-crystalline phase pure nano-sized hydroxyapatite. Effect of microwave power, retention time and the concentration of reactants on the phase purity, degree of crystallinity and surface area of the final product was studied in detail. X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) were used to study the phase purity and composition of the product, while transmission electron microscopy (TEM) was used to study the effect of process parameters on the morphology of hydroxyapatite. The TEM analysis confirmed the formation of spherical particles at low microwave power; however the morphology of the particles changed to mesoporous needle and rod-like structure upon exposing the reaction mixture to higher microwave power and longer retention time inside the microwave. The in-vitro ion dissolution behavior of the as synthesized hydroxyapatite was studied by determining the amount of Ca2+ ion released in SBF solution. Elsevier Ltd. 2015 Article PeerReviewed Akram, Muhammad and Alshemary, Ammar Z. and Goh, Yi Fan and Wan Ibrahim, Wan Aini and Lintang, Hendrik Oktendy and Hussain, Rafaqat (2015) Continuous microwave flow synthesis of mesoporous hydroxyapatite. Materials Science and Engineering C, 56 . pp. 356-362. ISSN 0928-4931 http://dx.doi.org/10.1016/j.msec.2015.06.040 DOI:10.1016/j.msec.2015.06.040 |
| spellingShingle | QD Chemistry Akram, Muhammad Alshemary, Ammar Z. Goh, Yi Fan Wan Ibrahim, Wan Aini Lintang, Hendrik Oktendy Hussain, Rafaqat Continuous microwave flow synthesis of mesoporous hydroxyapatite |
| title | Continuous microwave flow synthesis of mesoporous hydroxyapatite |
| title_full | Continuous microwave flow synthesis of mesoporous hydroxyapatite |
| title_fullStr | Continuous microwave flow synthesis of mesoporous hydroxyapatite |
| title_full_unstemmed | Continuous microwave flow synthesis of mesoporous hydroxyapatite |
| title_short | Continuous microwave flow synthesis of mesoporous hydroxyapatite |
| title_sort | continuous microwave flow synthesis of mesoporous hydroxyapatite |
| topic | QD Chemistry |
| work_keys_str_mv | AT akrammuhammad continuousmicrowaveflowsynthesisofmesoporoushydroxyapatite AT alshemaryammarz continuousmicrowaveflowsynthesisofmesoporoushydroxyapatite AT gohyifan continuousmicrowaveflowsynthesisofmesoporoushydroxyapatite AT wanibrahimwanaini continuousmicrowaveflowsynthesisofmesoporoushydroxyapatite AT lintanghendrikoktendy continuousmicrowaveflowsynthesisofmesoporoushydroxyapatite AT hussainrafaqat continuousmicrowaveflowsynthesisofmesoporoushydroxyapatite |