Two-stage robust estimators for product concentration in a penicillin fermentation

Two strategies are proposed for inferential estimations of penicillin concentration in a fed-batch fermentation process. The first scheme employs a partial least squares (PLS)-based estimator to directly estimate the intended product concentration. The second introduces a two-step estimation where b...

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Main Authors: Chow, A. W., Ahmad, Arshad
Format: Conference or Workshop Item
Language:English
Published: 2004
Subjects:
Online Access:http://eprints.utm.my/5944/1/A.W.Chow2004_TwoStageRobustEstimatorsForProduct.pdf
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author Chow, A. W.
Ahmad, Arshad
author_facet Chow, A. W.
Ahmad, Arshad
author_sort Chow, A. W.
collection ePrints
description Two strategies are proposed for inferential estimations of penicillin concentration in a fed-batch fermentation process. The first scheme employs a partial least squares (PLS)-based estimator to directly estimate the intended product concentration. The second introduces a two-step estimation where biomass concentration is first estimated and used as the input to the final estimator along with other process variables. The results confirmed the strength of the two-stage approach. To further extend the capability of the estimation scheme, a wavelet-based filter is added to the estimation model. The improved performance obtained proved the efficacy of the wavelet filter.
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spelling utm.eprints-59442017-09-10T08:29:38Z http://eprints.utm.my/5944/ Two-stage robust estimators for product concentration in a penicillin fermentation Chow, A. W. Ahmad, Arshad T Technology (General) Two strategies are proposed for inferential estimations of penicillin concentration in a fed-batch fermentation process. The first scheme employs a partial least squares (PLS)-based estimator to directly estimate the intended product concentration. The second introduces a two-step estimation where biomass concentration is first estimated and used as the input to the final estimator along with other process variables. The results confirmed the strength of the two-stage approach. To further extend the capability of the estimation scheme, a wavelet-based filter is added to the estimation model. The improved performance obtained proved the efficacy of the wavelet filter. 2004 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.utm.my/5944/1/A.W.Chow2004_TwoStageRobustEstimatorsForProduct.pdf Chow, A. W. and Ahmad, Arshad (2004) Two-stage robust estimators for product concentration in a penicillin fermentation. In: 18th Symposium of Malaysian Chemical Engineers (SOMChe) 2004, 13 - 14 Dec. 2004, UTP, Perak, Malaysia.
spellingShingle T Technology (General)
Chow, A. W.
Ahmad, Arshad
Two-stage robust estimators for product concentration in a penicillin fermentation
title Two-stage robust estimators for product concentration in a penicillin fermentation
title_full Two-stage robust estimators for product concentration in a penicillin fermentation
title_fullStr Two-stage robust estimators for product concentration in a penicillin fermentation
title_full_unstemmed Two-stage robust estimators for product concentration in a penicillin fermentation
title_short Two-stage robust estimators for product concentration in a penicillin fermentation
title_sort two stage robust estimators for product concentration in a penicillin fermentation
topic T Technology (General)
url http://eprints.utm.my/5944/1/A.W.Chow2004_TwoStageRobustEstimatorsForProduct.pdf
work_keys_str_mv AT chowaw twostagerobustestimatorsforproductconcentrationinapenicillinfermentation
AT ahmadarshad twostagerobustestimatorsforproductconcentrationinapenicillinfermentation