Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract
In this present investigation, AgNPs were green synthesised using Coriandrum sativum leaf extract. The physicochemical properties of AgNPs were characterised using UV–visible spectrophotometer, field emission scanning microscopy/energy dispersive X-ray (FESEM/EDX), Fourier transformed infrared spect...
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| Format: | Article |
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Elsevier B.V.
2016
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| _version_ | 1796861872996089856 |
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| author | Sathishkumar, P. Preethi, J. Vijayan, R. Mohd. Yusoff, A. R. Ameen, F. Suresh, S. Balagurunathan, R. Palvannan, T. |
| author_facet | Sathishkumar, P. Preethi, J. Vijayan, R. Mohd. Yusoff, A. R. Ameen, F. Suresh, S. Balagurunathan, R. Palvannan, T. |
| author_sort | Sathishkumar, P. |
| collection | ePrints |
| description | In this present investigation, AgNPs were green synthesised using Coriandrum sativum leaf extract. The physicochemical properties of AgNPs were characterised using UV–visible spectrophotometer, field emission scanning microscopy/energy dispersive X-ray (FESEM/EDX), Fourier transformed infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and Brunauer-Emmett-Teller (BET) analysis. Further, in vitro anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised AgNPs were assessed against Propionibacterium acnes MTCC 1951, Malassezia furfur MTCC 1374 and human breast adenocarcinoma (MCF-7) cell line, respectively. The flavonoids present in the plant extract were responsible for the AgNPs synthesis. The green synthesised nanoparticles size was found to be ≈ 37 nm. The BET analysis result shows that the surface area of the synthesised AgNPs was found to be 33.72 m2 g− 1. The minimal inhibitory concentration (MIC) of AgNPs for acne causative agent P. acnes and dandruff causative agent M. furfur was found to be at 3.1 and 25 μg mL− 1, respectively. The half maximal inhibitory concentration (IC50) value of the AgNPs for MCF-7 cells was calculated as 30.5 μg mL− 1 and complete inhibition was observed at a concentration of 100 μg mL− 1. Finally, our results proved that green synthesised AgNPs using C. sativum have great potential in biomedical applications such as anti-acne, anti-dandruff and anti-breast cancer treatment. |
| first_indexed | 2024-03-05T20:03:00Z |
| format | Article |
| id | utm.eprints-72069 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T20:03:00Z |
| publishDate | 2016 |
| publisher | Elsevier B.V. |
| record_format | dspace |
| spelling | utm.eprints-720692017-11-20T08:18:52Z http://eprints.utm.my/72069/ Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract Sathishkumar, P. Preethi, J. Vijayan, R. Mohd. Yusoff, A. R. Ameen, F. Suresh, S. Balagurunathan, R. Palvannan, T. TP Chemical technology In this present investigation, AgNPs were green synthesised using Coriandrum sativum leaf extract. The physicochemical properties of AgNPs were characterised using UV–visible spectrophotometer, field emission scanning microscopy/energy dispersive X-ray (FESEM/EDX), Fourier transformed infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and Brunauer-Emmett-Teller (BET) analysis. Further, in vitro anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised AgNPs were assessed against Propionibacterium acnes MTCC 1951, Malassezia furfur MTCC 1374 and human breast adenocarcinoma (MCF-7) cell line, respectively. The flavonoids present in the plant extract were responsible for the AgNPs synthesis. The green synthesised nanoparticles size was found to be ≈ 37 nm. The BET analysis result shows that the surface area of the synthesised AgNPs was found to be 33.72 m2 g− 1. The minimal inhibitory concentration (MIC) of AgNPs for acne causative agent P. acnes and dandruff causative agent M. furfur was found to be at 3.1 and 25 μg mL− 1, respectively. The half maximal inhibitory concentration (IC50) value of the AgNPs for MCF-7 cells was calculated as 30.5 μg mL− 1 and complete inhibition was observed at a concentration of 100 μg mL− 1. Finally, our results proved that green synthesised AgNPs using C. sativum have great potential in biomedical applications such as anti-acne, anti-dandruff and anti-breast cancer treatment. Elsevier B.V. 2016 Article PeerReviewed Sathishkumar, P. and Preethi, J. and Vijayan, R. and Mohd. Yusoff, A. R. and Ameen, F. and Suresh, S. and Balagurunathan, R. and Palvannan, T. (2016) Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract. Journal of Photochemistry and Photobiology B: Biology, 163 . pp. 69-76. ISSN 1011-1344 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982111850&doi=10.1016%2fj.jphotobiol.2016.08.005&partnerID=40&md5=63ddb7b2f6ca27f1e007472e06232afd |
| spellingShingle | TP Chemical technology Sathishkumar, P. Preethi, J. Vijayan, R. Mohd. Yusoff, A. R. Ameen, F. Suresh, S. Balagurunathan, R. Palvannan, T. Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract |
| title | Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract |
| title_full | Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract |
| title_fullStr | Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract |
| title_full_unstemmed | Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract |
| title_short | Anti-acne, anti-dandruff and anti-breast cancer efficacy of green synthesised silver nanoparticles using Coriandrum sativum leaf extract |
| title_sort | anti acne anti dandruff and anti breast cancer efficacy of green synthesised silver nanoparticles using coriandrum sativum leaf extract |
| topic | TP Chemical technology |
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