Frequency-controlled wireless shape memory polymer microactuator for drug delivery application
This paper reports the wireless Shape-Memory-Polymer actuator operated by external radio frequency magnetic fields and its application in a drug delivery device. The actuator is driven by a frequency-sensitive wireless resonant heater which is bonded directly to the Shape-Memory-Polymer and is activ...
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| Format: | Article |
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Springer New York LLC
2017
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| _version_ | 1796862341407571968 |
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| author | Zainal, M. A. Ahmad, A. Mohamed Ali, M. S. |
| author_facet | Zainal, M. A. Ahmad, A. Mohamed Ali, M. S. |
| author_sort | Zainal, M. A. |
| collection | ePrints |
| description | This paper reports the wireless Shape-Memory-Polymer actuator operated by external radio frequency magnetic fields and its application in a drug delivery device. The actuator is driven by a frequency-sensitive wireless resonant heater which is bonded directly to the Shape-Memory-Polymer and is activated only when the field frequency is tuned to the resonant frequency of heater. The heater is fabricated using a double-sided Cu-clad Polyimide with much simpler fabrication steps compared to previously reported methods. The actuation range of 140 μm as the tip opening distance is achieved at device temperature 44 °C in 30 s using 0.05 W RF power. A repeatability test shows that the actuator’s average maximum displacement is 110 μm and standard deviation of 12 μm. An experiment is conducted to demonstrate drug release with 5 μL of an acidic solution loaded in the reservoir and the device is immersed in DI water. The actuator is successfully operated in water through wireless activation. The acidic solution is released and diffused in water with an average release rate of 0.172 μL/min. |
| first_indexed | 2024-03-05T20:10:10Z |
| format | Article |
| id | utm.eprints-75433 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T20:10:10Z |
| publishDate | 2017 |
| publisher | Springer New York LLC |
| record_format | dspace |
| spelling | utm.eprints-754332018-03-21T00:41:36Z http://eprints.utm.my/75433/ Frequency-controlled wireless shape memory polymer microactuator for drug delivery application Zainal, M. A. Ahmad, A. Mohamed Ali, M. S. TK Electrical engineering. Electronics Nuclear engineering This paper reports the wireless Shape-Memory-Polymer actuator operated by external radio frequency magnetic fields and its application in a drug delivery device. The actuator is driven by a frequency-sensitive wireless resonant heater which is bonded directly to the Shape-Memory-Polymer and is activated only when the field frequency is tuned to the resonant frequency of heater. The heater is fabricated using a double-sided Cu-clad Polyimide with much simpler fabrication steps compared to previously reported methods. The actuation range of 140 μm as the tip opening distance is achieved at device temperature 44 °C in 30 s using 0.05 W RF power. A repeatability test shows that the actuator’s average maximum displacement is 110 μm and standard deviation of 12 μm. An experiment is conducted to demonstrate drug release with 5 μL of an acidic solution loaded in the reservoir and the device is immersed in DI water. The actuator is successfully operated in water through wireless activation. The acidic solution is released and diffused in water with an average release rate of 0.172 μL/min. Springer New York LLC 2017 Article PeerReviewed Zainal, M. A. and Ahmad, A. and Mohamed Ali, M. S. (2017) Frequency-controlled wireless shape memory polymer microactuator for drug delivery application. Biomedical Microdevices, 19 (1). ISSN 1387-2176 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85010840332&doi=10.1007%2fs10544-017-0148-5&partnerID=40&md5=2f0cc955ff59113d0eecf9b9b8d4086f |
| spellingShingle | TK Electrical engineering. Electronics Nuclear engineering Zainal, M. A. Ahmad, A. Mohamed Ali, M. S. Frequency-controlled wireless shape memory polymer microactuator for drug delivery application |
| title | Frequency-controlled wireless shape memory polymer microactuator for drug delivery application |
| title_full | Frequency-controlled wireless shape memory polymer microactuator for drug delivery application |
| title_fullStr | Frequency-controlled wireless shape memory polymer microactuator for drug delivery application |
| title_full_unstemmed | Frequency-controlled wireless shape memory polymer microactuator for drug delivery application |
| title_short | Frequency-controlled wireless shape memory polymer microactuator for drug delivery application |
| title_sort | frequency controlled wireless shape memory polymer microactuator for drug delivery application |
| topic | TK Electrical engineering. Electronics Nuclear engineering |
| work_keys_str_mv | AT zainalma frequencycontrolledwirelessshapememorypolymermicroactuatorfordrugdeliveryapplication AT ahmada frequencycontrolledwirelessshapememorypolymermicroactuatorfordrugdeliveryapplication AT mohamedalims frequencycontrolledwirelessshapememorypolymermicroactuatorfordrugdeliveryapplication |