Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys
The effects of bismuth (Bi) addition on the microstructure and corrosion behavior of the Mg-Ca-Zn-Bi alloys were evaluated using electron microscopy, electrochemical test and electrochemical impedance spectroscopy. Microstructural observations showed that Mg-1.2Ca-1Zn-xBi (x = 0.5, 1.5, 3 wt.%) are...
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Springer New York LLC
2017
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| author | Bakhsheshi-Rad, H. R. Hamzah, E. Tok, H. Y. Kasiri-Asgarani, M. Jabbarzare, S. Medraj, M. |
| author_facet | Bakhsheshi-Rad, H. R. Hamzah, E. Tok, H. Y. Kasiri-Asgarani, M. Jabbarzare, S. Medraj, M. |
| author_sort | Bakhsheshi-Rad, H. R. |
| collection | ePrints |
| description | The effects of bismuth (Bi) addition on the microstructure and corrosion behavior of the Mg-Ca-Zn-Bi alloys were evaluated using electron microscopy, electrochemical test and electrochemical impedance spectroscopy. Microstructural observations showed that Mg-1.2Ca-1Zn-xBi (x = 0.5, 1.5, 3 wt.%) are composed of Mg2Ca, Ca2Mg6Zn3 and Mg3Bi2 phases while a new phase Mg2Bi2Ca appeared after the addition of 5 and 12 wt.% Bi to the Mg-1.2Ca-1Zn alloy. Furthermore, the additions of 0.5 wt.% Bi to the Mg-1.2Ca-1Zn alloy slightly improved the corrosion behavior of the alloy, while further increase in Bi amount from 1.5 to 12 wt.% has a deleterious effect on the corrosion behavior of the ternary Mg-1.2Ca-1Zn alloy which is driven by galvanic coupling effect. Cytotoxicity tests indicate that the Mg-1.2Ca-1Zn presents higher cell viability compared to Mg-1.2Ca-1Zn-0.5Bi alloy. In addition, the cell viability of both alloys increased with increasing incubation time while diluting the extracts to 50% and 10% improved the cell viabilities. The present results suggest that the Mg-1.2Ca-1Zn-0.5Bi can be interesting candidate for the development of degradable biomaterials and it is worthwhile for further investigation in an in vivo environment. |
| first_indexed | 2024-03-05T20:12:44Z |
| format | Article |
| id | utm.eprints-76469 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T20:12:44Z |
| publishDate | 2017 |
| publisher | Springer New York LLC |
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| spelling | utm.eprints-764692018-05-31T09:21:10Z http://eprints.utm.my/76469/ Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys Bakhsheshi-Rad, H. R. Hamzah, E. Tok, H. Y. Kasiri-Asgarani, M. Jabbarzare, S. Medraj, M. TJ Mechanical engineering and machinery The effects of bismuth (Bi) addition on the microstructure and corrosion behavior of the Mg-Ca-Zn-Bi alloys were evaluated using electron microscopy, electrochemical test and electrochemical impedance spectroscopy. Microstructural observations showed that Mg-1.2Ca-1Zn-xBi (x = 0.5, 1.5, 3 wt.%) are composed of Mg2Ca, Ca2Mg6Zn3 and Mg3Bi2 phases while a new phase Mg2Bi2Ca appeared after the addition of 5 and 12 wt.% Bi to the Mg-1.2Ca-1Zn alloy. Furthermore, the additions of 0.5 wt.% Bi to the Mg-1.2Ca-1Zn alloy slightly improved the corrosion behavior of the alloy, while further increase in Bi amount from 1.5 to 12 wt.% has a deleterious effect on the corrosion behavior of the ternary Mg-1.2Ca-1Zn alloy which is driven by galvanic coupling effect. Cytotoxicity tests indicate that the Mg-1.2Ca-1Zn presents higher cell viability compared to Mg-1.2Ca-1Zn-0.5Bi alloy. In addition, the cell viability of both alloys increased with increasing incubation time while diluting the extracts to 50% and 10% improved the cell viabilities. The present results suggest that the Mg-1.2Ca-1Zn-0.5Bi can be interesting candidate for the development of degradable biomaterials and it is worthwhile for further investigation in an in vivo environment. Springer New York LLC 2017 Article PeerReviewed Bakhsheshi-Rad, H. R. and Hamzah, E. and Tok, H. Y. and Kasiri-Asgarani, M. and Jabbarzare, S. and Medraj, M. (2017) Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys. Journal of Materials Engineering and Performance, 26 (2). pp. 653-666. ISSN 1059+9495 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85008692965&doi=10.1007%2fs11665-016-2499-0&partnerID=40&md5=2ff5ad8a01ebc852f70757d5d2470048 DOI:10.1007/s11665-016-2499-0 |
| spellingShingle | TJ Mechanical engineering and machinery Bakhsheshi-Rad, H. R. Hamzah, E. Tok, H. Y. Kasiri-Asgarani, M. Jabbarzare, S. Medraj, M. Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys |
| title | Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys |
| title_full | Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys |
| title_fullStr | Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys |
| title_full_unstemmed | Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys |
| title_short | Microstructure, in vitro corrosion behavior and cytotoxicity of biodegradable Mg-Ca-Zn and Mg-Ca-Zn-Bi alloys |
| title_sort | microstructure in vitro corrosion behavior and cytotoxicity of biodegradable mg ca zn and mg ca zn bi alloys |
| topic | TJ Mechanical engineering and machinery |
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