Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste

The hazards of dumping medical plastics have created a huge demand to reduce the quantity of plastic usage without compromising its quality. The metallocene synthesized polyethylene is one such advent, however, its clinical usage is limited by the problem of hemocompatibility. This study investigate...

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Main Authors: Jaganathan, S. K., Balaji, A., Mohandas, H., Sivakumar, G., Kasi, P., Selvakumar, M., Kadiman, S. B., Srinivasan, A., Mohd. Faudzi, A. A. B., Supriyanto, E., Mandal, M.
Format: Article
Published: Taylor and Francis Inc. 2017
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author Jaganathan, S. K.
Balaji, A.
Mohandas, H.
Sivakumar, G.
Kasi, P.
Selvakumar, M.
Kadiman, S. B.
Srinivasan, A.
Mohd. Faudzi, A. A. B.
Supriyanto, E.
Mandal, M.
author_facet Jaganathan, S. K.
Balaji, A.
Mohandas, H.
Sivakumar, G.
Kasi, P.
Selvakumar, M.
Kadiman, S. B.
Srinivasan, A.
Mohd. Faudzi, A. A. B.
Supriyanto, E.
Mandal, M.
author_sort Jaganathan, S. K.
collection ePrints
description The hazards of dumping medical plastics have created a huge demand to reduce the quantity of plastic usage without compromising its quality. The metallocene synthesized polyethylene is one such advent, however, its clinical usage is limited by the problem of hemocompatibility. This study investigates the effect of sulfuric acid-induced changes in metallocene polyethylene. Fourier transform infrared spectroscopy analysis illustrated the addition of OH and sulfonic acid group, which subsequently increased the wettability. An improvement in micro as well as nanosurface roughness was observed. Ultimately, the treated surfaces depicted delayed clotting time, adsorption of specific plasma proteins, reduced hemolysis, and resistance against platelet adhesion.
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spelling utm.eprints-770472018-04-30T14:36:40Z http://eprints.utm.my/77047/ Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste Jaganathan, S. K. Balaji, A. Mohandas, H. Sivakumar, G. Kasi, P. Selvakumar, M. Kadiman, S. B. Srinivasan, A. Mohd. Faudzi, A. A. B. Supriyanto, E. Mandal, M. TP Chemical technology The hazards of dumping medical plastics have created a huge demand to reduce the quantity of plastic usage without compromising its quality. The metallocene synthesized polyethylene is one such advent, however, its clinical usage is limited by the problem of hemocompatibility. This study investigates the effect of sulfuric acid-induced changes in metallocene polyethylene. Fourier transform infrared spectroscopy analysis illustrated the addition of OH and sulfonic acid group, which subsequently increased the wettability. An improvement in micro as well as nanosurface roughness was observed. Ultimately, the treated surfaces depicted delayed clotting time, adsorption of specific plasma proteins, reduced hemolysis, and resistance against platelet adhesion. Taylor and Francis Inc. 2017 Article PeerReviewed Jaganathan, S. K. and Balaji, A. and Mohandas, H. and Sivakumar, G. and Kasi, P. and Selvakumar, M. and Kadiman, S. B. and Srinivasan, A. and Mohd. Faudzi, A. A. B. and Supriyanto, E. and Mandal, M. (2017) Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste. Polymer - Plastics Technology and Engineering, 56 (3). pp. 240-253. ISSN 0360-2559 https://www.scopus.com/inward/record.uri?eid=2-s2.0-85009973192&doi=10.1080%2f03602559.2016.1211696&partnerID=40&md5=32aefe4c0f40024ea1292f232270456e DOI:10.1080/03602559.2016.1211696
spellingShingle TP Chemical technology
Jaganathan, S. K.
Balaji, A.
Mohandas, H.
Sivakumar, G.
Kasi, P.
Selvakumar, M.
Kadiman, S. B.
Srinivasan, A.
Mohd. Faudzi, A. A. B.
Supriyanto, E.
Mandal, M.
Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste
title Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste
title_full Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste
title_fullStr Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste
title_full_unstemmed Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste
title_short Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste
title_sort hemocompatibility of sulfuric acid treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste
topic TP Chemical technology
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