Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber

The demands for an antimicrobial agent of natural origin has increasingly grown in recent years due to the adverse health effects from the long-term application of conventional chemical-based agent. To date, there are very few reports available on the use of pyroligneous acid produced in optimized c...

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Main Authors: Abas, F. Z., Zakaria, Z. A., Ani, F. N.
Format: Article
Language:English
Published: Open Science Publishers LLP Inc. 2018
Subjects:
Online Access:http://eprints.utm.my/79860/1/FatimatulZaharahAbas2018_AntimicrobialPropertiesofOptimizedMicrowaveAssisted.pdf
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author Abas, F. Z.
Zakaria, Z. A.
Ani, F. N.
author_facet Abas, F. Z.
Zakaria, Z. A.
Ani, F. N.
author_sort Abas, F. Z.
collection ePrints
description The demands for an antimicrobial agent of natural origin has increasingly grown in recent years due to the adverse health effects from the long-term application of conventional chemical-based agent. To date, there are very few reports available on the use of pyroligneous acid produced in optimized condition, as antimicrobial agent. Thus, this study reports on the evaluation of the antimicrobial properties of oil palm fiber-derived pyroligneous acid produced using microwave heating at optimum condition (MWPA). The optimized MWPA was concentrated and extracted using ethyl acetate and was further determined for its antimicrobial properties against Gram positive and Gram negative bacterial strains through Minimum Inhibitory Concentration (MIC) and Minimum Biocidal Concentration (MBC) analysis. Results obtained shows that MWPA exhibited high inhibition zone that varied between 13 ± 0.58 to 28.67 ± 0.88 mm toward all strains screened in the present study with low range of MIC value from 0.651 ± 0.13 to 1.563 ± 0.00 mg/ml. This indicated that CPAEA MWPA derived from OPF exhibited a strong antimicrobial activity and might be projected as alternative natural source as antimicrobial agent.
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spelling utm.eprints-798602019-01-28T06:58:19Z http://eprints.utm.my/79860/ Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber Abas, F. Z. Zakaria, Z. A. Ani, F. N. TP Chemical technology The demands for an antimicrobial agent of natural origin has increasingly grown in recent years due to the adverse health effects from the long-term application of conventional chemical-based agent. To date, there are very few reports available on the use of pyroligneous acid produced in optimized condition, as antimicrobial agent. Thus, this study reports on the evaluation of the antimicrobial properties of oil palm fiber-derived pyroligneous acid produced using microwave heating at optimum condition (MWPA). The optimized MWPA was concentrated and extracted using ethyl acetate and was further determined for its antimicrobial properties against Gram positive and Gram negative bacterial strains through Minimum Inhibitory Concentration (MIC) and Minimum Biocidal Concentration (MBC) analysis. Results obtained shows that MWPA exhibited high inhibition zone that varied between 13 ± 0.58 to 28.67 ± 0.88 mm toward all strains screened in the present study with low range of MIC value from 0.651 ± 0.13 to 1.563 ± 0.00 mg/ml. This indicated that CPAEA MWPA derived from OPF exhibited a strong antimicrobial activity and might be projected as alternative natural source as antimicrobial agent. Open Science Publishers LLP Inc. 2018 Article PeerReviewed application/pdf en http://eprints.utm.my/79860/1/FatimatulZaharahAbas2018_AntimicrobialPropertiesofOptimizedMicrowaveAssisted.pdf Abas, F. Z. and Zakaria, Z. A. and Ani, F. N. (2018) Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber. Journal of Applied Pharmaceutical Science, 8 (7). pp. 65-71. ISSN 2231-3354 http://dx.doi.org/10.7324/JAPS.2018.8711 DOI:10.7324/JAPS.2018.8711
spellingShingle TP Chemical technology
Abas, F. Z.
Zakaria, Z. A.
Ani, F. N.
Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber
title Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber
title_full Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber
title_fullStr Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber
title_full_unstemmed Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber
title_short Antimicrobial properties of optimized microwave-assisted Pyroligneous Acid from oil palm fiber
title_sort antimicrobial properties of optimized microwave assisted pyroligneous acid from oil palm fiber
topic TP Chemical technology
url http://eprints.utm.my/79860/1/FatimatulZaharahAbas2018_AntimicrobialPropertiesofOptimizedMicrowaveAssisted.pdf
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