Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite

A system of dual antibacterial agents loaded onto kaolinite (Kao) as carrier has been developed by attaching cetylpyridinium bromide (CPB) onto Ag-loaded Kao (Ag-Kao). The analysis of CPB adsorbed onto Ag-Kao and characterisation of the CPB-Ag-Kao systems using X-ray diffraction (XRD), energy-disper...

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Main Authors: Nik Malek, Nik Ahmad Nizam, Ramli, Nur Isti'Anah
Format: Conference or Workshop Item
Published: 2018
Subjects:
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author Nik Malek, Nik Ahmad Nizam
Ramli, Nur Isti'Anah
author_facet Nik Malek, Nik Ahmad Nizam
Ramli, Nur Isti'Anah
author_sort Nik Malek, Nik Ahmad Nizam
collection ePrints
description A system of dual antibacterial agents loaded onto kaolinite (Kao) as carrier has been developed by attaching cetylpyridinium bromide (CPB) onto Ag-loaded Kao (Ag-Kao). The analysis of CPB adsorbed onto Ag-Kao and characterisation of the CPB-Ag-Kao systems using X-ray diffraction (XRD), energy-dispersive X-ray (EDX) spectroscopy and Fourier-transform infrared (FTIR) spectroscopy demonstrated that the CPB molecules attached onto Ag-Kao and no changes occurred in the Kao structure. The antibacterial effect of different amounts of CPB and Ag attached onto Kao was investigated against Gram-positive (Staphylococcus aureus ATCC 6538) and Gram-negative (Escherichia coli ATCC 11229) bacteria. The antibacterial activity of CPB-Ag-Kao was higher than that of Ag-Kao and the highest antibacterial activity was recorded for CPB-Ag-Kao loaded with 50% Ag and 1000% CPB, which satisfied the cation exchange capacity of Kao. The higher antibacterial activity of CPB-Ag-Kao against a wide spectrum of bacteria was due to the synergistic effects of the two antibacterial agents loaded onto Kao as carrier.
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spelling utm.eprints-824262019-10-06T07:06:07Z http://eprints.utm.my/82426/ Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite Nik Malek, Nik Ahmad Nizam Ramli, Nur Isti'Anah Q Science (General) A system of dual antibacterial agents loaded onto kaolinite (Kao) as carrier has been developed by attaching cetylpyridinium bromide (CPB) onto Ag-loaded Kao (Ag-Kao). The analysis of CPB adsorbed onto Ag-Kao and characterisation of the CPB-Ag-Kao systems using X-ray diffraction (XRD), energy-dispersive X-ray (EDX) spectroscopy and Fourier-transform infrared (FTIR) spectroscopy demonstrated that the CPB molecules attached onto Ag-Kao and no changes occurred in the Kao structure. The antibacterial effect of different amounts of CPB and Ag attached onto Kao was investigated against Gram-positive (Staphylococcus aureus ATCC 6538) and Gram-negative (Escherichia coli ATCC 11229) bacteria. The antibacterial activity of CPB-Ag-Kao was higher than that of Ag-Kao and the highest antibacterial activity was recorded for CPB-Ag-Kao loaded with 50% Ag and 1000% CPB, which satisfied the cation exchange capacity of Kao. The higher antibacterial activity of CPB-Ag-Kao against a wide spectrum of bacteria was due to the synergistic effects of the two antibacterial agents loaded onto Kao as carrier. 2018 Conference or Workshop Item PeerReviewed Nik Malek, Nik Ahmad Nizam and Ramli, Nur Isti'Anah (2018) Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite. In: The 3rd International Conference of Materials Research Society of Indonesia (MRS-ID) Meeting 2018. http://dx.doi.org/10.1088/2053-1591/ab2e52
spellingShingle Q Science (General)
Nik Malek, Nik Ahmad Nizam
Ramli, Nur Isti'Anah
Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite
title Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite
title_full Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite
title_fullStr Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite
title_full_unstemmed Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite
title_short Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite
title_sort preparation and antibacterial properties of cetylpyridinium bromide modified silver loaded kaolinite
topic Q Science (General)
work_keys_str_mv AT nikmaleknikahmadnizam preparationandantibacterialpropertiesofcetylpyridiniumbromidemodifiedsilverloadedkaolinite
AT ramlinuristianah preparationandantibacterialpropertiesofcetylpyridiniumbromidemodifiedsilverloadedkaolinite