Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment
Polyethersulfon (PES) membrane has been widely used in the biomedical field especially in hemodialysis application. Many modifications of membranes have been applied into hemodialysis such as diffusion, adsorption, and mixed-matrix membrane. The main problem of those membranes is less selectivity to...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Penerbit UTM Press
2019
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| Online Access: | http://eprints.utm.my/84759/1/AhmadFauziIsmail2019_IncorporationofImprinted-ZeolitetoPolyethersulfone.pdf |
| _version_ | 1796863911117455360 |
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| author | Raharjo, Yanuardi Fahmi, Mochamad Zakki Wafiroh, Siti Widati, Alfa Akustia Amanda, Eviomitta Rizki Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Santoso, Djoko |
| author_facet | Raharjo, Yanuardi Fahmi, Mochamad Zakki Wafiroh, Siti Widati, Alfa Akustia Amanda, Eviomitta Rizki Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Santoso, Djoko |
| author_sort | Raharjo, Yanuardi |
| collection | ePrints |
| description | Polyethersulfon (PES) membrane has been widely used in the biomedical field especially in hemodialysis application. Many modifications of membranes have been applied into hemodialysis such as diffusion, adsorption, and mixed-matrix membrane. The main problem of those membranes is less selectivity to attract the uremic toxins. In this study, we report the modification of PES mixed with cellulose acetate (PES/CA) membrane as mixed-matrix membrane (MMM) using imprinted-zeolite (PES/CA/IZC) in order to increase the selectivity for targeted analyte. The hollow fibre membranes (HFM) were fabricated by dry-wet spinning technique. The successful zeolite A synthesised and was characterised by x-ray diffraction (XRD). The mixed-matrix membranes were characterised in terms of morphology using scanning electron microscopy (SEM), water contact angle (WCA), pure water flux (PWF), clearance of creatinine (CC), and BSA adsorption. In accordance with the results of characterisation, the synthesis of zeolite A, and imprinted-zeolite creatinine was successfully fabricated. The SEM results showed that the PES/CA/IZC membrane has uniform pores and fingerlike structure. The same result was obtained for PES/CA membrane, but not for PES/CA/ZA membrane. The WCA of the PES/CA; PES/CA/ZA; and PES/CA/IZC were 85.63; 84.98; and 77.53 (o), respectively. While the PWF were 22.84; 27.57, and 40.52 (Lm-2 h-1), respectively. The addition of imprinted-zeolite into the membrane improved creatinine removal up to 74.99%. It showed that PES/CA/IZC has succeeded in increasing the selectivity of membranes to attract the creatinine as target analyte. Compared to the PES/CA, the creatinine clearance of membranes improved and increased up to 5.2%. For protein rejection, the PES/CA/IZC rejected 79.05% of bovine serum albumin (BSA). Based on these results, it can be concluded that PES/CA/IZC can be considered as hemodialysis membranes.Polyethersulfon (PES) membrane has been widely used in the biomedical field especially in hemodialysis application. Many modifications of membranes have been applied into hemodialysis such as diffusion, adsorption, and mixed-matrix membrane. The main problem of those membranes is less selectivity to attract the uremic toxins. In this study, we report the modification of PES mixed with cellulose acetate (PES/CA) membrane as mixed-matrix membrane (MMM) using imprinted-zeolite (PES/CA/IZC) in order to increase the selectivity for targeted analyte. The hollow fibre membranes (HFM) were fabricated by dry-wet spinning technique. The successful zeolite A synthesised and was characterised by x-ray diffraction (XRD). The mixed-matrix membranes were characterised in terms of morphology using scanning electron microscopy (SEM), water contact angle (WCA), pure water flux (PWF), clearance of creatinine (CC), and BSA adsorption. In accordance with the results of characterisation, the synthesis of zeolite A, and imprinted-zeolite creatinine was successfully fabricated. The SEM results showed that the PES/CA/IZC membrane has uniform pores and fingerlike structure. The same result was obtained for PES/CA membrane, but not for PES/CA/ZA membrane. The WCA of the PES/CA; PES/CA/ZA; and PES/CA/IZC were 85.63; 84.98; and 77.53 (o), respectively. While the PWF were 22.84; 27.57, and 40.52 (Lm-2 h-1), respectively. The addition of imprinted-zeolite into the membrane improved creatinine removal up to 74.99%. It showed that PES/CA/IZC has succeeded in increasing the selectivity of membranes to attract the creatinine as target analyte. Compared to the PES/CA, the creatinine clearance of membranes improved and increased up to 5.2%. For protein rejection, the PES/CA/IZC rejected 79.05% of bovine serum albumin (BSA). Based on these results, it can be concluded that PES/CA/IZC can be considered as hemodialysis membranes. |
| first_indexed | 2024-03-05T20:33:48Z |
| format | Article |
| id | utm.eprints-84759 |
| institution | Universiti Teknologi Malaysia - ePrints |
| language | English |
| last_indexed | 2024-03-05T20:33:48Z |
| publishDate | 2019 |
| publisher | Penerbit UTM Press |
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| spelling | utm.eprints-847592020-02-27T04:59:13Z http://eprints.utm.my/84759/ Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment Raharjo, Yanuardi Fahmi, Mochamad Zakki Wafiroh, Siti Widati, Alfa Akustia Amanda, Eviomitta Rizki Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Santoso, Djoko TP Chemical technology Polyethersulfon (PES) membrane has been widely used in the biomedical field especially in hemodialysis application. Many modifications of membranes have been applied into hemodialysis such as diffusion, adsorption, and mixed-matrix membrane. The main problem of those membranes is less selectivity to attract the uremic toxins. In this study, we report the modification of PES mixed with cellulose acetate (PES/CA) membrane as mixed-matrix membrane (MMM) using imprinted-zeolite (PES/CA/IZC) in order to increase the selectivity for targeted analyte. The hollow fibre membranes (HFM) were fabricated by dry-wet spinning technique. The successful zeolite A synthesised and was characterised by x-ray diffraction (XRD). The mixed-matrix membranes were characterised in terms of morphology using scanning electron microscopy (SEM), water contact angle (WCA), pure water flux (PWF), clearance of creatinine (CC), and BSA adsorption. In accordance with the results of characterisation, the synthesis of zeolite A, and imprinted-zeolite creatinine was successfully fabricated. The SEM results showed that the PES/CA/IZC membrane has uniform pores and fingerlike structure. The same result was obtained for PES/CA membrane, but not for PES/CA/ZA membrane. The WCA of the PES/CA; PES/CA/ZA; and PES/CA/IZC were 85.63; 84.98; and 77.53 (o), respectively. While the PWF were 22.84; 27.57, and 40.52 (Lm-2 h-1), respectively. The addition of imprinted-zeolite into the membrane improved creatinine removal up to 74.99%. It showed that PES/CA/IZC has succeeded in increasing the selectivity of membranes to attract the creatinine as target analyte. Compared to the PES/CA, the creatinine clearance of membranes improved and increased up to 5.2%. For protein rejection, the PES/CA/IZC rejected 79.05% of bovine serum albumin (BSA). Based on these results, it can be concluded that PES/CA/IZC can be considered as hemodialysis membranes.Polyethersulfon (PES) membrane has been widely used in the biomedical field especially in hemodialysis application. Many modifications of membranes have been applied into hemodialysis such as diffusion, adsorption, and mixed-matrix membrane. The main problem of those membranes is less selectivity to attract the uremic toxins. In this study, we report the modification of PES mixed with cellulose acetate (PES/CA) membrane as mixed-matrix membrane (MMM) using imprinted-zeolite (PES/CA/IZC) in order to increase the selectivity for targeted analyte. The hollow fibre membranes (HFM) were fabricated by dry-wet spinning technique. The successful zeolite A synthesised and was characterised by x-ray diffraction (XRD). The mixed-matrix membranes were characterised in terms of morphology using scanning electron microscopy (SEM), water contact angle (WCA), pure water flux (PWF), clearance of creatinine (CC), and BSA adsorption. In accordance with the results of characterisation, the synthesis of zeolite A, and imprinted-zeolite creatinine was successfully fabricated. The SEM results showed that the PES/CA/IZC membrane has uniform pores and fingerlike structure. The same result was obtained for PES/CA membrane, but not for PES/CA/ZA membrane. The WCA of the PES/CA; PES/CA/ZA; and PES/CA/IZC were 85.63; 84.98; and 77.53 (o), respectively. While the PWF were 22.84; 27.57, and 40.52 (Lm-2 h-1), respectively. The addition of imprinted-zeolite into the membrane improved creatinine removal up to 74.99%. It showed that PES/CA/IZC has succeeded in increasing the selectivity of membranes to attract the creatinine as target analyte. Compared to the PES/CA, the creatinine clearance of membranes improved and increased up to 5.2%. For protein rejection, the PES/CA/IZC rejected 79.05% of bovine serum albumin (BSA). Based on these results, it can be concluded that PES/CA/IZC can be considered as hemodialysis membranes. Penerbit UTM Press 2019 Article PeerReviewed application/pdf en http://eprints.utm.my/84759/1/AhmadFauziIsmail2019_IncorporationofImprinted-ZeolitetoPolyethersulfone.pdf Raharjo, Yanuardi and Fahmi, Mochamad Zakki and Wafiroh, Siti and Widati, Alfa Akustia and Amanda, Eviomitta Rizki and Ismail, Ahmad Fauzi and Othman, Mohd. Hafiz Dzarfan and Santoso, Djoko (2019) Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment. Jurnal Teknologi, 81 (3). pp. 137-144. ISSN 2180-3722 https://dx.doi.org/10.11113/jt.v81.13075 DOI:10.11113/jt.v81.13075 |
| spellingShingle | TP Chemical technology Raharjo, Yanuardi Fahmi, Mochamad Zakki Wafiroh, Siti Widati, Alfa Akustia Amanda, Eviomitta Rizki Ismail, Ahmad Fauzi Othman, Mohd. Hafiz Dzarfan Santoso, Djoko Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment |
| title | Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment |
| title_full | Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment |
| title_fullStr | Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment |
| title_full_unstemmed | Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment |
| title_short | Incorporation of imprinted-zeolite to polyethersulfone/cellulose acetate membrane for creatinine removal in hemodialysis treatment |
| title_sort | incorporation of imprinted zeolite to polyethersulfone cellulose acetate membrane for creatinine removal in hemodialysis treatment |
| topic | TP Chemical technology |
| url | http://eprints.utm.my/84759/1/AhmadFauziIsmail2019_IncorporationofImprinted-ZeolitetoPolyethersulfone.pdf |
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