Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design

Zingiber zerumbet was reported to has chemo preventive effects and was suggested as one of the therapeutic treatments for cancer. In this study, Z. zerumbet was extracted using subcritical water extraction (SWE) by employing two level full factorial design. 2k full factorial design was employed usin...

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Main Authors: Mohamad Abdul Wahab, Izzati, Firdhaus Mad Nordin, Mariam, Mohd. Amir, Siti Nur Khairunisa
Format: Article
Language:English
Published: Penerbit UTM Press 2019
Subjects:
Online Access:http://eprints.utm.my/84977/1/MariamFirdhausMadNordin2019_SubcriticalWaterExtraction%28SWE%29ofZingiber.pdf
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author Mohamad Abdul Wahab, Izzati
Firdhaus Mad Nordin, Mariam
Mohd. Amir, Siti Nur Khairunisa
author_facet Mohamad Abdul Wahab, Izzati
Firdhaus Mad Nordin, Mariam
Mohd. Amir, Siti Nur Khairunisa
author_sort Mohamad Abdul Wahab, Izzati
collection ePrints
description Zingiber zerumbet was reported to has chemo preventive effects and was suggested as one of the therapeutic treatments for cancer. In this study, Z. zerumbet was extracted using subcritical water extraction (SWE) by employing two level full factorial design. 2k full factorial design was employed using 18 runs with 10 repeats in central points. The independent variables factors were temperature (100-150°C), time (10-30 minutes) and material ratio (1:10 and 1:20 g/ml) for the evaluation of highest zerumbone concentration and overall yield of extracted Z. zerumbet. Effects of extraction temperature and time were found to be significant on all responses with p-value <0.05. However, the material ratio only gave significant effect on the zerumbone concentration and less significant on the yield. In addition, the value of curvature was found to be significant, thus indicating the relation between the independent variables and the response was linear. Therefore, it was found that the concentration of zerumbone and yield from Z. zerumbet extracted by SWE were significantly affected by temperature and time of extraction.
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spelling utm.eprints-849772020-02-29T13:49:12Z http://eprints.utm.my/84977/ Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design Mohamad Abdul Wahab, Izzati Firdhaus Mad Nordin, Mariam Mohd. Amir, Siti Nur Khairunisa TP Chemical technology Zingiber zerumbet was reported to has chemo preventive effects and was suggested as one of the therapeutic treatments for cancer. In this study, Z. zerumbet was extracted using subcritical water extraction (SWE) by employing two level full factorial design. 2k full factorial design was employed using 18 runs with 10 repeats in central points. The independent variables factors were temperature (100-150°C), time (10-30 minutes) and material ratio (1:10 and 1:20 g/ml) for the evaluation of highest zerumbone concentration and overall yield of extracted Z. zerumbet. Effects of extraction temperature and time were found to be significant on all responses with p-value <0.05. However, the material ratio only gave significant effect on the zerumbone concentration and less significant on the yield. In addition, the value of curvature was found to be significant, thus indicating the relation between the independent variables and the response was linear. Therefore, it was found that the concentration of zerumbone and yield from Z. zerumbet extracted by SWE were significantly affected by temperature and time of extraction. Penerbit UTM Press 2019 Article PeerReviewed application/pdf en http://eprints.utm.my/84977/1/MariamFirdhausMadNordin2019_SubcriticalWaterExtraction%28SWE%29ofZingiber.pdf Mohamad Abdul Wahab, Izzati and Firdhaus Mad Nordin, Mariam and Mohd. Amir, Siti Nur Khairunisa (2019) Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design. Malaysian Journal of Fundamental and Applied Sciences, 15 (2). pp. 139-145. ISSN 2289-5981 https://dx.doi.org/10.11113/mjfas.v15n2.1204 DOI:10.11113/mjfas.v15n2.1204
spellingShingle TP Chemical technology
Mohamad Abdul Wahab, Izzati
Firdhaus Mad Nordin, Mariam
Mohd. Amir, Siti Nur Khairunisa
Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design
title Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design
title_full Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design
title_fullStr Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design
title_full_unstemmed Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design
title_short Subcritical water extraction (SWE) of Zingiber zerumbet using two level full factorial design
title_sort subcritical water extraction swe of zingiber zerumbet using two level full factorial design
topic TP Chemical technology
url http://eprints.utm.my/84977/1/MariamFirdhausMadNordin2019_SubcriticalWaterExtraction%28SWE%29ofZingiber.pdf
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AT mohdamirsitinurkhairunisa subcriticalwaterextractionsweofzingiberzerumbetusingtwolevelfullfactorialdesign