Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes

Flat sheet asymmetric dialysis membranes were fabricated using phase inversion method from polymer solution consisting of cellulose acetate, acetic acid, polyethylene glycol (PEG) and distilled water. The effect of acetic acid/PEG ratio and the distilled water content in the dialysis membrane were b...

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Main Authors: Idris, Ani, Lee, Kuan Yet, Noordin, M. Y., Chan, Mieow Kee
Format: Article
Language:English
Published: Penerbit UTM Press 2008
Subjects:
Online Access:http://eprints.utm.my/8509/1/UTMjurnalTEK_49F_DIS%5B04%5D.pdf
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author Idris, Ani
Lee, Kuan Yet
Noordin, M. Y.
Chan, Mieow Kee
author_facet Idris, Ani
Lee, Kuan Yet
Noordin, M. Y.
Chan, Mieow Kee
author_sort Idris, Ani
collection ePrints
description Flat sheet asymmetric dialysis membranes were fabricated using phase inversion method from polymer solution consisting of cellulose acetate, acetic acid, polyethylene glycol (PEG) and distilled water. The effect of acetic acid/PEG ratio and the distilled water content in the dialysis membrane were being investigated with respect to the urea clearance performance. Response surface methodology (RSM) was used to design the experiments and analysed the results obtained. The analysis revealed that the significant factor that affects the cellulose acetate dialysis membrane performance in terms of urea clearance is the ratio of acetic acid/PEG. Dialysis membrane with higher ratio of acetic acid/PEG gives higher urea clearance percentage due to the formation of finger like macrovoids. The relation between the urea clearance and the ratio of acetic acid/PEG in the given range of 4 – 14, was a quadratic model and the mathematical model suggested could adequately describe the performance indicators within the limits mentioned.
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spelling utm.eprints-85092010-10-14T04:47:15Z http://eprints.utm.my/8509/ Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes Idris, Ani Lee, Kuan Yet Noordin, M. Y. Chan, Mieow Kee TP Chemical technology Flat sheet asymmetric dialysis membranes were fabricated using phase inversion method from polymer solution consisting of cellulose acetate, acetic acid, polyethylene glycol (PEG) and distilled water. The effect of acetic acid/PEG ratio and the distilled water content in the dialysis membrane were being investigated with respect to the urea clearance performance. Response surface methodology (RSM) was used to design the experiments and analysed the results obtained. The analysis revealed that the significant factor that affects the cellulose acetate dialysis membrane performance in terms of urea clearance is the ratio of acetic acid/PEG. Dialysis membrane with higher ratio of acetic acid/PEG gives higher urea clearance percentage due to the formation of finger like macrovoids. The relation between the urea clearance and the ratio of acetic acid/PEG in the given range of 4 – 14, was a quadratic model and the mathematical model suggested could adequately describe the performance indicators within the limits mentioned. Penerbit UTM Press 2008-12 Article PeerReviewed application/pdf en http://eprints.utm.my/8509/1/UTMjurnalTEK_49F_DIS%5B04%5D.pdf Idris, Ani and Lee, Kuan Yet and Noordin, M. Y. and Chan, Mieow Kee (2008) Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes. Jurnal Teknologi F (49F). pp. 39-49. ISSN 0127-9696
spellingShingle TP Chemical technology
Idris, Ani
Lee, Kuan Yet
Noordin, M. Y.
Chan, Mieow Kee
Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes
title Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes
title_full Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes
title_fullStr Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes
title_full_unstemmed Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes
title_short Response surface methodology approach to study the influence of PEG and water in cellulose acetate dialysis membranes
title_sort response surface methodology approach to study the influence of peg and water in cellulose acetate dialysis membranes
topic TP Chemical technology
url http://eprints.utm.my/8509/1/UTMjurnalTEK_49F_DIS%5B04%5D.pdf
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