The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells
The effects of cinnamtannin BI on cell proliferation and glucose uptake of 3T3-L1 cells were examined. Cinnamtannin BI promoted cell proliferation of 3T3-L1 adipocytes at a concentration range between 0. 11-0. 17 mM. The effect of cinnamtannin 131 on cellular 2-deoxy-D-[1-H-3] glucose uptake in diff...
| मुख्य लेखकों: | , , |
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| स्वरूप: | लेख |
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Natural Products Inc
2007
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| विषय: |
| _version_ | 1825910243147644928 |
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| author | Taher, Muhammad Abdul Majid, Fadzilah Adibah Sarmidi, Mohamad Roji |
| author_facet | Taher, Muhammad Abdul Majid, Fadzilah Adibah Sarmidi, Mohamad Roji |
| author_sort | Taher, Muhammad |
| collection | ePrints |
| description | The effects of cinnamtannin BI on cell proliferation and glucose uptake of 3T3-L1 cells were examined. Cinnamtannin BI promoted cell proliferation of 3T3-L1 adipocytes at a concentration range between 0. 11-0. 17 mM. The effect of cinnamtannin 131 on cellular 2-deoxy-D-[1-H-3] glucose uptake in differentiated 3T3-L1 adipocytes, following treatment with a 0.11 rnM concentration of cinnamtannin B1 for 15, 30 and 60 minutes, was an increase in the glucose uptake from a basal value to 702.0, 1111.0 and 2226.0 cpm, respectively (p<0.005). The comparable glucose uptakes with insulin treatment were 660.0, 1039.0 and 2135.0 cpm, respectively. Wortmannin and cytochalasin B were found to inhibit cinnamtannin B1-stimulated glucose uptake, but sodium orthovanadate increased the glucose uptake. |
| first_indexed | 2024-03-05T18:14:11Z |
| format | Article |
| id | utm.eprints-8725 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T18:14:11Z |
| publishDate | 2007 |
| publisher | Natural Products Inc |
| record_format | dspace |
| spelling | utm.eprints-87252017-10-19T01:33:43Z http://eprints.utm.my/8725/ The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells Taher, Muhammad Abdul Majid, Fadzilah Adibah Sarmidi, Mohamad Roji TP Chemical technology The effects of cinnamtannin BI on cell proliferation and glucose uptake of 3T3-L1 cells were examined. Cinnamtannin BI promoted cell proliferation of 3T3-L1 adipocytes at a concentration range between 0. 11-0. 17 mM. The effect of cinnamtannin 131 on cellular 2-deoxy-D-[1-H-3] glucose uptake in differentiated 3T3-L1 adipocytes, following treatment with a 0.11 rnM concentration of cinnamtannin B1 for 15, 30 and 60 minutes, was an increase in the glucose uptake from a basal value to 702.0, 1111.0 and 2226.0 cpm, respectively (p<0.005). The comparable glucose uptakes with insulin treatment were 660.0, 1039.0 and 2135.0 cpm, respectively. Wortmannin and cytochalasin B were found to inhibit cinnamtannin B1-stimulated glucose uptake, but sodium orthovanadate increased the glucose uptake. Natural Products Inc 2007 Article PeerReviewed Taher, Muhammad and Abdul Majid, Fadzilah Adibah and Sarmidi, Mohamad Roji (2007) The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells. Natural Product Communications, 2 (1). pp. 61-66. ISSN 1934-578X |
| spellingShingle | TP Chemical technology Taher, Muhammad Abdul Majid, Fadzilah Adibah Sarmidi, Mohamad Roji The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells |
| title | The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells |
| title_full | The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells |
| title_fullStr | The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells |
| title_full_unstemmed | The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells |
| title_short | The effect of cinnamtannin B1 on cell proliferation and glucose uptake of 3T3-L1 cells |
| title_sort | effect of cinnamtannin b1 on cell proliferation and glucose uptake of 3t3 l1 cells |
| topic | TP Chemical technology |
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