A simulation study of cell separation in microfluidic channel based on hydrodynamic principle
Separation micro-particles based on physical characteristics is important in numerous applications such as diagnostics, biological analyses, food industries and chemical processing. Microfluidic devices have emerged as a multifunctional and powerful platform for separation ranging from nano-micro si...
| Main Authors: | , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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2019
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| Online Access: | http://eprints.utm.my/88545/1/MohdRidzuanAhmad2019_ASimulationStudyofCellSeparation.pdf |
| _version_ | 1796864651758141440 |
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| author | Ahmad, M. R. Mansor, M. A. Ahmad, I. L. |
| author_facet | Ahmad, M. R. Mansor, M. A. Ahmad, I. L. |
| author_sort | Ahmad, M. R. |
| collection | ePrints |
| description | Separation micro-particles based on physical characteristics is important in numerous applications such as diagnostics, biological analyses, food industries and chemical processing. Microfluidic devices have emerged as a multifunctional and powerful platform for separation ranging from nano-micro sized particles to biological cells. This paper presents a simulation study for microparticle separation in a microfluidic channel based on hydrodynamic technique. By exploiting the hydrodynamic properties of the fluid flow and physical characteristics of microparticles, effective size-based separation is demonstrated. The objectives of the simulations are to obtain the appropriate channels’ angle to separate micro-particle. The analysis of effects of taper angle for microparticle separation was carried out using numerical solutions from the finite element ABAQUS-FEA software. The taper angles 20ºand 25ºare successfully separate the mixture of 1000 kgm-3 and 10000 kgm-3 density microparticle. |
| first_indexed | 2024-03-05T20:45:04Z |
| format | Conference or Workshop Item |
| id | utm.eprints-88545 |
| institution | Universiti Teknologi Malaysia - ePrints |
| language | English |
| last_indexed | 2024-03-05T20:45:04Z |
| publishDate | 2019 |
| record_format | dspace |
| spelling | utm.eprints-885452020-12-15T10:31:12Z http://eprints.utm.my/88545/ A simulation study of cell separation in microfluidic channel based on hydrodynamic principle Ahmad, M. R. Mansor, M. A. Ahmad, I. L. TK Electrical engineering. Electronics Nuclear engineering Separation micro-particles based on physical characteristics is important in numerous applications such as diagnostics, biological analyses, food industries and chemical processing. Microfluidic devices have emerged as a multifunctional and powerful platform for separation ranging from nano-micro sized particles to biological cells. This paper presents a simulation study for microparticle separation in a microfluidic channel based on hydrodynamic technique. By exploiting the hydrodynamic properties of the fluid flow and physical characteristics of microparticles, effective size-based separation is demonstrated. The objectives of the simulations are to obtain the appropriate channels’ angle to separate micro-particle. The analysis of effects of taper angle for microparticle separation was carried out using numerical solutions from the finite element ABAQUS-FEA software. The taper angles 20ºand 25ºare successfully separate the mixture of 1000 kgm-3 and 10000 kgm-3 density microparticle. 2019 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.utm.my/88545/1/MohdRidzuanAhmad2019_ASimulationStudyofCellSeparation.pdf Ahmad, M. R. and Mansor, M. A. and Ahmad, I. L. (2019) A simulation study of cell separation in microfluidic channel based on hydrodynamic principle. In: 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018, 3-6 Dec 2018, Borneo Convention Centre Kuching Demak-Isthmus Bridge, Jalan Keruing, Sejingkat Kuching, Malaysia. https://dx.doi.org/10.1109/IECBES.2018.8626646 |
| spellingShingle | TK Electrical engineering. Electronics Nuclear engineering Ahmad, M. R. Mansor, M. A. Ahmad, I. L. A simulation study of cell separation in microfluidic channel based on hydrodynamic principle |
| title | A simulation study of cell separation in microfluidic channel based on hydrodynamic principle |
| title_full | A simulation study of cell separation in microfluidic channel based on hydrodynamic principle |
| title_fullStr | A simulation study of cell separation in microfluidic channel based on hydrodynamic principle |
| title_full_unstemmed | A simulation study of cell separation in microfluidic channel based on hydrodynamic principle |
| title_short | A simulation study of cell separation in microfluidic channel based on hydrodynamic principle |
| title_sort | simulation study of cell separation in microfluidic channel based on hydrodynamic principle |
| topic | TK Electrical engineering. Electronics Nuclear engineering |
| url | http://eprints.utm.my/88545/1/MohdRidzuanAhmad2019_ASimulationStudyofCellSeparation.pdf |
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