Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications
This article focuses on providing a systematic review on various fundamental properties of composite based on poly(α-hydroxy esters) and hydroxyapatite (HAp) for application in bone tissue engineering. Poly(α-hydroxy esters), a well-known synthetic biopolymer has attracted considerable interest to b...
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| Format: | Article |
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Taylor and Francis Inc.
2019
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| _version_ | 1796864823893426176 |
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| author | Ng, Hon Meng Bee, Soo Tueen Lee, Tin Sin Ratnam, Chantara T. Rahmat, Abdul Razak |
| author_facet | Ng, Hon Meng Bee, Soo Tueen Lee, Tin Sin Ratnam, Chantara T. Rahmat, Abdul Razak |
| author_sort | Ng, Hon Meng |
| collection | ePrints |
| description | This article focuses on providing a systematic review on various fundamental properties of composite based on poly(α-hydroxy esters) and hydroxyapatite (HAp) for application in bone tissue engineering. Poly(α-hydroxy esters), a well-known synthetic biopolymer has attracted considerable interest to be employed for synthesis of bone graft substitute material with HAp mainly due to its bioresorbability, variable biodegradation rate and melt-processibility. Such features are simultaneously attractive for both biomedical application and industrial-scale productions. Besides the main function of hydroxyapatite as bioactive ceramic filler in composite to induce new bone formation upon polymer bioresorption, HAp can also serve as reinforcement for matrix polymer by providing sufficient mechanical support for cell attachment. Moreover, HAp plays a significant role in determining other composite properties, such as resistance to ingress of body fluid, body temperature ageing, relaxation movement of polymer segment, and in vivo biodegradation. These properties constitute as the fundamental requirements in field of bone tissue regeneration which is desirable to be achieved by unique composite system based on poly(α-hydroxyesters) and HAp particles. |
| first_indexed | 2024-03-05T20:47:36Z |
| format | Article |
| id | utm.eprints-89406 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T20:47:36Z |
| publishDate | 2019 |
| publisher | Taylor and Francis Inc. |
| record_format | dspace |
| spelling | utm.eprints-894062021-02-22T06:04:35Z http://eprints.utm.my/89406/ Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications Ng, Hon Meng Bee, Soo Tueen Lee, Tin Sin Ratnam, Chantara T. Rahmat, Abdul Razak TP Chemical technology This article focuses on providing a systematic review on various fundamental properties of composite based on poly(α-hydroxy esters) and hydroxyapatite (HAp) for application in bone tissue engineering. Poly(α-hydroxy esters), a well-known synthetic biopolymer has attracted considerable interest to be employed for synthesis of bone graft substitute material with HAp mainly due to its bioresorbability, variable biodegradation rate and melt-processibility. Such features are simultaneously attractive for both biomedical application and industrial-scale productions. Besides the main function of hydroxyapatite as bioactive ceramic filler in composite to induce new bone formation upon polymer bioresorption, HAp can also serve as reinforcement for matrix polymer by providing sufficient mechanical support for cell attachment. Moreover, HAp plays a significant role in determining other composite properties, such as resistance to ingress of body fluid, body temperature ageing, relaxation movement of polymer segment, and in vivo biodegradation. These properties constitute as the fundamental requirements in field of bone tissue regeneration which is desirable to be achieved by unique composite system based on poly(α-hydroxyesters) and HAp particles. Taylor and Francis Inc. 2019-04-03 Article PeerReviewed Ng, Hon Meng and Bee, Soo Tueen and Lee, Tin Sin and Ratnam, Chantara T. and Rahmat, Abdul Razak (2019) Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications. Polymer Reviews, 59 (2). pp. 187-239. ISSN 1558-3724 http://dx.doi.org/10.1080/15583724.2018.1488729 DOI:10.1080/15583724.2018.1488729 |
| spellingShingle | TP Chemical technology Ng, Hon Meng Bee, Soo Tueen Lee, Tin Sin Ratnam, Chantara T. Rahmat, Abdul Razak Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications |
| title | Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications |
| title_full | Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications |
| title_fullStr | Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications |
| title_full_unstemmed | Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications |
| title_short | Hydroxyapatite for poly(alpha-hydroxy esters) biocomposites applications |
| title_sort | hydroxyapatite for poly alpha hydroxy esters biocomposites applications |
| topic | TP Chemical technology |
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