Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method
The present diabetes epidemic highlights the need for adequate and efficient drugs. The implementation of alternative and complementary medicinal products becomes a high priority. Many trials disclosed Carica papaya's anti-diabetic function, but its function in taking up glucose was not fully d...
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| Format: | Article |
| Language: | English |
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Rynnye Lyan Resources
2020
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| Online Access: | http://eprints.utm.my/93296/1/HarisunYaakob2020_EvaluationOfAntiDiabeticActivityOfCaricaPapaya.pdf |
| _version_ | 1796865593807208448 |
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| author | Elhaj, R. A. Yaakob, H. Abd. Malek, R. |
| author_facet | Elhaj, R. A. Yaakob, H. Abd. Malek, R. |
| author_sort | Elhaj, R. A. |
| collection | ePrints |
| description | The present diabetes epidemic highlights the need for adequate and efficient drugs. The implementation of alternative and complementary medicinal products becomes a high priority. Many trials disclosed Carica papaya's anti-diabetic function, but its function in taking up glucose was not fully discovered. Therefore, this study aimed to evaluate the rate of glucose uptake across the cell membrane in the yeast cell system in the presence of C. papaya aqueous extract in different concentrations (1 mg, 2 mg, 3 mg, 4 mg, 5 mg) at different glucose concentrations (5 mM, 10 mM, 25 mM). The results showed that a linear improvement in the transport of glucose a cross yeast was comparable to Metformin at different glucose concentrations. The maximum glucose uptake was 76% in 5 mg of aqueous extract of C. papaya at 5 mM glucose concentration. The finding of this study may be useful for future research and the development of a new natural product to treat diabetes mellitus. |
| first_indexed | 2024-03-05T20:59:22Z |
| format | Article |
| id | utm.eprints-93296 |
| institution | Universiti Teknologi Malaysia - ePrints |
| language | English |
| last_indexed | 2024-03-05T20:59:22Z |
| publishDate | 2020 |
| publisher | Rynnye Lyan Resources |
| record_format | dspace |
| spelling | utm.eprints-932962021-11-19T03:23:47Z http://eprints.utm.my/93296/ Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method Elhaj, R. A. Yaakob, H. Abd. Malek, R. TP Chemical technology The present diabetes epidemic highlights the need for adequate and efficient drugs. The implementation of alternative and complementary medicinal products becomes a high priority. Many trials disclosed Carica papaya's anti-diabetic function, but its function in taking up glucose was not fully discovered. Therefore, this study aimed to evaluate the rate of glucose uptake across the cell membrane in the yeast cell system in the presence of C. papaya aqueous extract in different concentrations (1 mg, 2 mg, 3 mg, 4 mg, 5 mg) at different glucose concentrations (5 mM, 10 mM, 25 mM). The results showed that a linear improvement in the transport of glucose a cross yeast was comparable to Metformin at different glucose concentrations. The maximum glucose uptake was 76% in 5 mg of aqueous extract of C. papaya at 5 mM glucose concentration. The finding of this study may be useful for future research and the development of a new natural product to treat diabetes mellitus. Rynnye Lyan Resources 2020 Article PeerReviewed application/pdf en http://eprints.utm.my/93296/1/HarisunYaakob2020_EvaluationOfAntiDiabeticActivityOfCaricaPapaya.pdf Elhaj, R. A. and Yaakob, H. and Abd. Malek, R. (2020) Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method. Food Research, 4 . pp. 67-70. ISSN 2550-2166 http://dx.doi.org/10.26656/fr.2017.4(S2).S01 |
| spellingShingle | TP Chemical technology Elhaj, R. A. Yaakob, H. Abd. Malek, R. Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method |
| title | Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method |
| title_full | Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method |
| title_fullStr | Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method |
| title_full_unstemmed | Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method |
| title_short | Evaluation of anti-diabetic activity of Carica papaya leaves extract using yeast cells method |
| title_sort | evaluation of anti diabetic activity of carica papaya leaves extract using yeast cells method |
| topic | TP Chemical technology |
| url | http://eprints.utm.my/93296/1/HarisunYaakob2020_EvaluationOfAntiDiabeticActivityOfCaricaPapaya.pdf |
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