Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits

The consumption of noni fruits has been linked to several health benefits, many of which are attributed to scopoletin, alizarin and rutin that are present in the fruits. However, there is no report on optimized high hydrostatic pressure (HHP) extraction of noni fruits. In this study, the effects of...

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Main Authors: Jamaludin, R., Kim, D. S., Md. Salleh, L., Lim, S. B.
Format: Article
Published: Springer 2020
Subjects:
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author Jamaludin, R.
Kim, D. S.
Md. Salleh, L.
Lim, S. B.
author_facet Jamaludin, R.
Kim, D. S.
Md. Salleh, L.
Lim, S. B.
author_sort Jamaludin, R.
collection ePrints
description The consumption of noni fruits has been linked to several health benefits, many of which are attributed to scopoletin, alizarin and rutin that are present in the fruits. However, there is no report on optimized high hydrostatic pressure (HHP) extraction of noni fruits. In this study, the effects of ethanol concentration, pressure and time were evaluated individually on the extraction yields of bioactive compounds from noni fruits. The optimum extraction condition was then investigated to maximize the yields using response surface methodology with a Box-Behnken Design. The extraction pressure and ethanol concentration were the most statistically significant variables in obtaining high extraction yields. The optimal HHP extraction condition at the highest desirability (> 0.998) for simultaneous extraction of scopoletin, alizarin and rutin was as follows: pressure 544 MPa, time 15 min and ethanol concentration 65%, which gave the maximum yields of 82.4, 77.2 and 82.2% for scopoletin, alizarin and rutin, respectively. All bioactive compounds showed the positive linear and negative quadratic effects of pressure, the negative linear and negative quadratic effects of ethanol concentration, and the negative interaction effect between pressure and ethanol concentration on extraction yields. This study highlights the applicability of HHP in extracting bioactive compounds from noni fruits, taking advantage of high yield, extraction time saving and reduced solvent volume at room temperature.
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spelling utm.eprints-937582021-12-31T08:44:39Z http://eprints.utm.my/93758/ Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits Jamaludin, R. Kim, D. S. Md. Salleh, L. Lim, S. B. TP Chemical technology The consumption of noni fruits has been linked to several health benefits, many of which are attributed to scopoletin, alizarin and rutin that are present in the fruits. However, there is no report on optimized high hydrostatic pressure (HHP) extraction of noni fruits. In this study, the effects of ethanol concentration, pressure and time were evaluated individually on the extraction yields of bioactive compounds from noni fruits. The optimum extraction condition was then investigated to maximize the yields using response surface methodology with a Box-Behnken Design. The extraction pressure and ethanol concentration were the most statistically significant variables in obtaining high extraction yields. The optimal HHP extraction condition at the highest desirability (> 0.998) for simultaneous extraction of scopoletin, alizarin and rutin was as follows: pressure 544 MPa, time 15 min and ethanol concentration 65%, which gave the maximum yields of 82.4, 77.2 and 82.2% for scopoletin, alizarin and rutin, respectively. All bioactive compounds showed the positive linear and negative quadratic effects of pressure, the negative linear and negative quadratic effects of ethanol concentration, and the negative interaction effect between pressure and ethanol concentration on extraction yields. This study highlights the applicability of HHP in extracting bioactive compounds from noni fruits, taking advantage of high yield, extraction time saving and reduced solvent volume at room temperature. Springer 2020 Article PeerReviewed Jamaludin, R. and Kim, D. S. and Md. Salleh, L. and Lim, S. B. (2020) Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits. Journal of Food Measurement and Characterization, 14 (5). ISSN 2193-4126 http://dx.doi.org/10.1007/s11694-020-00526-w DOI: 10.1007/s11694-020-00526-w
spellingShingle TP Chemical technology
Jamaludin, R.
Kim, D. S.
Md. Salleh, L.
Lim, S. B.
Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits
title Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits
title_full Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits
title_fullStr Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits
title_full_unstemmed Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits
title_short Optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits
title_sort optimization of high hydrostatic pressure extraction of bioactive compounds from noni fruits
topic TP Chemical technology
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AT mdsallehl optimizationofhighhydrostaticpressureextractionofbioactivecompoundsfromnonifruits
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