Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review

This review focuses on the occurrence and distribution of 17 targeted human pharmaceutical compounds from the most common therapeutic classes. These include one analgesic (acetaminophen), three non-steroidal anti-inflammatory drugs (NSAIDs) (acetylsalicylic acid, diclofenac, ibuprofen), two antidiab...

Full description

Bibliographic Details
Main Authors: Hashim, N., Yuzir, A., Al-Qaim, F. F., Yahaya, N. K. E. M.
Format: Article
Language:English
Published: Sociedad Quimica de Mexico A.C. 2021
Subjects:
Online Access:http://eprints.utm.my/95062/1/NorbayaHashim2021_OccurrenceandDistribution.pdf
_version_ 1796865945783762944
author Hashim, N.
Yuzir, A.
Al-Qaim, F. F.
Yahaya, N. K. E. M.
author_facet Hashim, N.
Yuzir, A.
Al-Qaim, F. F.
Yahaya, N. K. E. M.
author_sort Hashim, N.
collection ePrints
description This review focuses on the occurrence and distribution of 17 targeted human pharmaceutical compounds from the most common therapeutic classes. These include one analgesic (acetaminophen), three non-steroidal anti-inflammatory drugs (NSAIDs) (acetylsalicylic acid, diclofenac, ibuprofen), two antidiabetic drugs (gliclazide, metformin), three antihistamines (cetirizine, chlorphenamine, ranitidine), four antihypertensives (amlodipine, atenolol, metoprolol, prazosin), one lipid regulator (simvastatin), one anti-convulsant (carbamazepine), one bronchodilator agent (salbutamol) and one stimulant (caffeine) which have been detected globally in various aquatic environmental matrices such as surface water, drinking water, ground water, seawater, influent and effluent of municipal wastewater treatment plants (WWTPs), hospital and industrial treatment plants, among others. The most common analytical method used involved solid phase extraction (SPE) and liquid chromatography coupled to mass spectrometry. The concentrations of all drugs investigated in all aqueous matrices varied from 0.5 to 85,000 ng/L for the highest concentration in the aqueous matrices in Southeast Asia. This review provides the first compilation on human pharmaceuticals in Southeast Asia in surface water, domestic wastewater (influent and effluent) and drinking water.
first_indexed 2024-03-05T21:04:49Z
format Article
id utm.eprints-95062
institution Universiti Teknologi Malaysia - ePrints
language English
last_indexed 2024-03-05T21:04:49Z
publishDate 2021
publisher Sociedad Quimica de Mexico A.C.
record_format dspace
spelling utm.eprints-950622022-04-29T22:02:06Z http://eprints.utm.my/95062/ Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review Hashim, N. Yuzir, A. Al-Qaim, F. F. Yahaya, N. K. E. M. T Technology (General) This review focuses on the occurrence and distribution of 17 targeted human pharmaceutical compounds from the most common therapeutic classes. These include one analgesic (acetaminophen), three non-steroidal anti-inflammatory drugs (NSAIDs) (acetylsalicylic acid, diclofenac, ibuprofen), two antidiabetic drugs (gliclazide, metformin), three antihistamines (cetirizine, chlorphenamine, ranitidine), four antihypertensives (amlodipine, atenolol, metoprolol, prazosin), one lipid regulator (simvastatin), one anti-convulsant (carbamazepine), one bronchodilator agent (salbutamol) and one stimulant (caffeine) which have been detected globally in various aquatic environmental matrices such as surface water, drinking water, ground water, seawater, influent and effluent of municipal wastewater treatment plants (WWTPs), hospital and industrial treatment plants, among others. The most common analytical method used involved solid phase extraction (SPE) and liquid chromatography coupled to mass spectrometry. The concentrations of all drugs investigated in all aqueous matrices varied from 0.5 to 85,000 ng/L for the highest concentration in the aqueous matrices in Southeast Asia. This review provides the first compilation on human pharmaceuticals in Southeast Asia in surface water, domestic wastewater (influent and effluent) and drinking water. Sociedad Quimica de Mexico A.C. 2021 Article PeerReviewed application/pdf en http://eprints.utm.my/95062/1/NorbayaHashim2021_OccurrenceandDistribution.pdf Hashim, N. and Yuzir, A. and Al-Qaim, F. F. and Yahaya, N. K. E. M. (2021) Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review. Journal of the Mexican Chemical Society, 65 (3). ISSN 1870-249X http://dx.doi.org/10.29356/jmcs.v65i3.1487 DOI: 10.29356/jmcs.v65i3.1487
spellingShingle T Technology (General)
Hashim, N.
Yuzir, A.
Al-Qaim, F. F.
Yahaya, N. K. E. M.
Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review
title Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review
title_full Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review
title_fullStr Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review
title_full_unstemmed Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review
title_short Occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia: a comprehensive review
title_sort occurrence and distribution of 17 targeted human pharmaceuticals in various aquatic environmental matrices in southeast asia with particular reference to malaysia a comprehensive review
topic T Technology (General)
url http://eprints.utm.my/95062/1/NorbayaHashim2021_OccurrenceandDistribution.pdf
work_keys_str_mv AT hashimn occurrenceanddistributionof17targetedhumanpharmaceuticalsinvariousaquaticenvironmentalmatricesinsoutheastasiawithparticularreferencetomalaysiaacomprehensivereview
AT yuzira occurrenceanddistributionof17targetedhumanpharmaceuticalsinvariousaquaticenvironmentalmatricesinsoutheastasiawithparticularreferencetomalaysiaacomprehensivereview
AT alqaimff occurrenceanddistributionof17targetedhumanpharmaceuticalsinvariousaquaticenvironmentalmatricesinsoutheastasiawithparticularreferencetomalaysiaacomprehensivereview
AT yahayankem occurrenceanddistributionof17targetedhumanpharmaceuticalsinvariousaquaticenvironmentalmatricesinsoutheastasiawithparticularreferencetomalaysiaacomprehensivereview