Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute

In biomedical application, the fabrication of biodegradable scaffolds using 3D printing technology has vastly increased to accommodate the complex structure of substitutes. In this study, PLLA and PDLA were hot-melt extruded for the 3D printing of PLLA/PDLA scaffolds. The incorporation of PDLA into...

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Main Authors: Jumat, Mohamad Amin, Chevallier, Pascale, Mantovani, Diego, Copes, Francesco, Abd. Razak, Saiful Izwan, Saidin, Syafiqah
Format: Article
Published: Bellwether Publishing, Ltd. 2021
Subjects:
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author Jumat, Mohamad Amin
Chevallier, Pascale
Mantovani, Diego
Copes, Francesco
Abd. Razak, Saiful Izwan
Saidin, Syafiqah
author_facet Jumat, Mohamad Amin
Chevallier, Pascale
Mantovani, Diego
Copes, Francesco
Abd. Razak, Saiful Izwan
Saidin, Syafiqah
author_sort Jumat, Mohamad Amin
collection ePrints
description In biomedical application, the fabrication of biodegradable scaffolds using 3D printing technology has vastly increased to accommodate the complex structure of substitutes. In this study, PLLA and PDLA were hot-melt extruded for the 3D printing of PLLA/PDLA scaffolds. The incorporation of PDLA into the PLLA has enhanced the hydrophobicity and mechanical properties of the scaffolds. The degraded PLLA/PDLA scaffolds were observed to retain its chemical functionalities. Less crack formation, less acidity of the degraded solution, higher percentages of remaining weight, greater average molecular weight, and higher crystallinity percentages were recorded on the higher PDLA composition after the degradation analysis.
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institution Universiti Teknologi Malaysia - ePrints
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publisher Bellwether Publishing, Ltd.
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spelling utm.eprints-950992022-04-29T22:24:01Z http://eprints.utm.my/95099/ Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute Jumat, Mohamad Amin Chevallier, Pascale Mantovani, Diego Copes, Francesco Abd. Razak, Saiful Izwan Saidin, Syafiqah TP Chemical technology In biomedical application, the fabrication of biodegradable scaffolds using 3D printing technology has vastly increased to accommodate the complex structure of substitutes. In this study, PLLA and PDLA were hot-melt extruded for the 3D printing of PLLA/PDLA scaffolds. The incorporation of PDLA into the PLLA has enhanced the hydrophobicity and mechanical properties of the scaffolds. The degraded PLLA/PDLA scaffolds were observed to retain its chemical functionalities. Less crack formation, less acidity of the degraded solution, higher percentages of remaining weight, greater average molecular weight, and higher crystallinity percentages were recorded on the higher PDLA composition after the degradation analysis. Bellwether Publishing, Ltd. 2021 Article PeerReviewed Jumat, Mohamad Amin and Chevallier, Pascale and Mantovani, Diego and Copes, Francesco and Abd. Razak, Saiful Izwan and Saidin, Syafiqah (2021) Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute. Polymer-Plastics Technology and Materials, 60 (9). pp. 1005-1015. ISSN 2574-0881 http://dx.doi.org/10.1080/25740881.2021.1876879
spellingShingle TP Chemical technology
Jumat, Mohamad Amin
Chevallier, Pascale
Mantovani, Diego
Copes, Francesco
Abd. Razak, Saiful Izwan
Saidin, Syafiqah
Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute
title Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute
title_full Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute
title_fullStr Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute
title_full_unstemmed Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute
title_short Three-dimensional printed biodegradable poly(l-lactic acid)/(poly(d-lactic acid) scaffold as an intervention of biomedical substitute
title_sort three dimensional printed biodegradable poly l lactic acid poly d lactic acid scaffold as an intervention of biomedical substitute
topic TP Chemical technology
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