Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite
This study evaluated the efficacy of antibacterial activities for a zeolite A (ZEO) sample loaded with streptomycin (STR). The ZEO was synthesized from kaolinite (KAO) via the alkaline hydrothermal process and verified with various techniques, such as X-ray Diffraction, Fourier-Transform Infrared sp...
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| Format: | Article |
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AMG Transcend Association
2021
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| _version_ | 1796865990185713664 |
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| author | Abdul Hadi, Atieya Nik Malek, Nik Ahmad Nizam Williams, Craig D. |
| author_facet | Abdul Hadi, Atieya Nik Malek, Nik Ahmad Nizam Williams, Craig D. |
| author_sort | Abdul Hadi, Atieya |
| collection | ePrints |
| description | This study evaluated the efficacy of antibacterial activities for a zeolite A (ZEO) sample loaded with streptomycin (STR). The ZEO was synthesized from kaolinite (KAO) via the alkaline hydrothermal process and verified with various techniques, such as X-ray Diffraction, Fourier-Transform Infrared spectroscopy, Field Emission Scanning Electron Microscopy with Energy Dispersive X-ray, Transmission Electron Microscopy, and dispersion behavior to confirm the production of ZEO with high purity and reproducibility. The cubic framework of ZEO was maintained after the immobilization of STR, indicating STR molecules' adsorption on the ZEO surface. The STR-loaded ZEO (ZS) samples were prepared in three STR concentrations (50, 100, and 200 mg/L). The samples' antibacterial activity was determined using the disc diffusion technique and minimum inhibition concentration against Gram-negative bacteria (Escherichia coli ATCC 11229) and Gram-positive bacteria (Staphylococcus aureus ATCC 6538). Both bacteria were susceptible to ZS, which showed an antibacterial effect directly proportional to the STR concentration. Thus, the synthesized ZEO synthesized from natural KAO had a good prospect as a carrier system for STR for generating a broad spectrum of antibacterial activity. |
| first_indexed | 2024-03-05T21:05:29Z |
| format | Article |
| id | utm.eprints-95285 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T21:05:29Z |
| publishDate | 2021 |
| publisher | AMG Transcend Association |
| record_format | dspace |
| spelling | utm.eprints-952852022-04-29T22:26:10Z http://eprints.utm.my/95285/ Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite Abdul Hadi, Atieya Nik Malek, Nik Ahmad Nizam Williams, Craig D. QD Chemistry This study evaluated the efficacy of antibacterial activities for a zeolite A (ZEO) sample loaded with streptomycin (STR). The ZEO was synthesized from kaolinite (KAO) via the alkaline hydrothermal process and verified with various techniques, such as X-ray Diffraction, Fourier-Transform Infrared spectroscopy, Field Emission Scanning Electron Microscopy with Energy Dispersive X-ray, Transmission Electron Microscopy, and dispersion behavior to confirm the production of ZEO with high purity and reproducibility. The cubic framework of ZEO was maintained after the immobilization of STR, indicating STR molecules' adsorption on the ZEO surface. The STR-loaded ZEO (ZS) samples were prepared in three STR concentrations (50, 100, and 200 mg/L). The samples' antibacterial activity was determined using the disc diffusion technique and minimum inhibition concentration against Gram-negative bacteria (Escherichia coli ATCC 11229) and Gram-positive bacteria (Staphylococcus aureus ATCC 6538). Both bacteria were susceptible to ZS, which showed an antibacterial effect directly proportional to the STR concentration. Thus, the synthesized ZEO synthesized from natural KAO had a good prospect as a carrier system for STR for generating a broad spectrum of antibacterial activity. AMG Transcend Association 2021 Article PeerReviewed Abdul Hadi, Atieya and Nik Malek, Nik Ahmad Nizam and Williams, Craig D. (2021) Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite. Biointerface Research in Applied Chemistry, 11 (5). pp. 13573-13586. ISSN 2069-5837 http://dx.doi.org/10.33263/BRIAC115.1357313586 |
| spellingShingle | QD Chemistry Abdul Hadi, Atieya Nik Malek, Nik Ahmad Nizam Williams, Craig D. Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite |
| title | Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite |
| title_full | Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite |
| title_fullStr | Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite |
| title_full_unstemmed | Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite |
| title_short | Structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite |
| title_sort | structural characterization and antibacterial activity of antibiotic streptomycin immobilized on zeolite synthesized from natural kaolinite |
| topic | QD Chemistry |
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