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Botulinum toxin: yesterday, today, tomorrow
Published 2015-02-01“…Botulinum toxin (BoNT) is a bacterial neurotoxin presented with seven serotypes that inhibit neurotransmitter release from nerve endings. …”
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On the absence of interchangeability of botulinum toxin type A drugs
Published 2015-12-01Subjects: Get full text
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Botulinum toxin type A chemodenervation treatment in spastic forms of cerebral palsy
Published 2015-02-01“…Being the key cause of pathological dynamic stereotypes that frequently result in pathological posture and contractures, spasticity is critically important for CP. The use of botulinum toxin type A (BTA) in complex treatment 2-6 years old CP patients allows significantly to improve motor abilities, help to change the surgical procedure, delay or even avoid some types of surgery. …”
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Use of botulinum toxin type A (Botox) in the treatment of infantile cerebral palsy
Published 2015-02-01“…Botulinum toxin type A (BoNT-A) is used in cerebral palsy (CP) for more than 20 years. …”
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EXPERIENCE OF THE TYPE A BOTULINUM TOXIN TYPE (ONABOTULINUMTOXINA) DRUG IN TREATMENT OF CEREBRAL PALSY PATIENTS
Published 2017-12-01Subjects: “…botulinum toxin type a…”
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IncobotulinumtoxinA in the treatment of sialorrhea in patients with infantile cerebral palsy
Published 2021-08-01“…The Drooling Impact (DIS) and the Global Impression of Change Scale (GICS) were used 1, 3 and 6 months after IncobotulinumtoxinA injections to assess treatment effectiveness.Results and discussion. Botulinum toxin therapy resulted in a significant decrease in saliva discharge from the oral cavity 1 and 3 months after IncobotulinumtoxinA injections, which was demonstrated by a reduction in mean DIS score from 78.6±9.6 (min 62, max 95 points; 95% CI 74.6—82.7) to 48.7±6.7(min 25, max 61 points; 95% CI45.8—51.6) and 52.7±8.5points (min 22, max 65; 95% CI49.1—56.3), respectively, as well as an increase in delta GICSscore up to +1.3+0.8(min 0, max 3points; 95% CI 1.0—1.6) and +1.0+0.7points (min 0, max 3points; 95% CI 0.8—1.3), respectively. …”
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