Changing survival, memory cell compartment, and T-helper balance of lymphocytes between severe and mild asthma by Abubakar F, Hafidh RR, Abdulamir AS, Abbas KA

“…Mild intermittent asthma is mainly Th2 allergen-oriented reaction during exacerbations with good level of apoptosis making the inflammation as self-limiting, while in severe persistent asthma, the inflammatory reaction mediated mainly by Th1 cytokines with progressive loss of apoptosis leading to longer exacerbations, largely expanded memory cells, CD45RO⁺, leading to persistent baseline inflammation.…”
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