10122 Development of an In Vitro in Vivo Correlation of Itraconazole Spray-Dried Dispersion Tablets by Ana Luisa Coutinho, Asmita Adhikari, James Polli

“…METHODS/STUDY POPULATION: This research project involves tablet manufacturing, in vitro dissolution experiments, and a clinical study. We manufactured fast-, medium-, and slow-release SDD tablets containing amorphous solid dispersion of itraconazole (100 mg) and different grades of the polymer hypromellose acetate succinate (HPMC-AS). …”
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