Preface, Morphogenesis issue by Maini, P, Baker, R

Mechanocellular models of epithelial morphogenesis by Fletcher, A, Cooper, F, Baker, R

“…In combination with experimental approaches, computational modelling allows us to challenge and refine our current understanding of epithelial morphogenesis and to explore experimentally intractable questions. …”

Quantitative approaches to investigating epithelial morphogenesis by Kursawe, J

“…<p>Morphogenesis - the generation of biological shape and form - is fascinating, and its study promises to shed light on a wide range of developmental defects and inform strategies for the artificial growth of organs. …”

A modified Oster-Murray-Harris mechanical model of morphogenesis by Vaughan, JR., B, Baker, R, Kay, D, Maini, P

A Modified Oster−Murray−Harris Mechanical Model of Morphogenesis by Jr, B, Baker, R, Kay, D, Maini, P

Visualizing mesoderm and neural crest cell dynamics during chick head morphogenesis by McKinney, M, McLennan, R, Giniunaite, R, Baker, R, Maini, P, Othmer, H, Kulesa, P

“…Vertebrate head morphogenesis involves carefully-orchestrated tissue growth and cell movements of the mesoderm and neural crest to form the distinct craniofacial pattern. …”

Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation. by Lin, C, Jiang, T, Baker, R, Maini, P, Widelitz, R, Chuong, C

Spots &amp; stripes: pleomorphic patterning of stem cells via p-ERK-depenendent cell chemotaxis shown by feather morphogenesis &amp; mathematical simulation by Lin, C, Jiang, T, Baker, R, Maini, P, Widelitz, R, Chunong, C

From segment to somite: segmentation to epithelialization analyzed within quantitative frameworks by Kulesa, P, Schnell, S, Rudloff, S, Baker, R, Maini, P

“…In this short review, we present two quantitative frameworks that address the morphogenesis from segment to somite and discuss recent data of segmentation and epithelialization.…”

From segment to somite: segmentation to epithelialization analyzed within quantitative frameworks. by Kulesa, P, Schnell, S, Rudloff, S, Baker, R, Maini, P

“…In this short review, we present two quantitative frameworks that address the morphogenesis from segment to somite and discuss recent data of segmentation and epithelialization.…”

Approximate Bayesian computation reveals the importance of repeated measurements for parameterising cell-based models of growing tissues by Kursawe, J, Baker, R, Fletcher, A

“…Increasingly, cell-based modelling approaches such as vertex models are being used to help understand the mechanics underlying epithelial morphogenesis. These models typically seek to reproduce qualitative phenomena, such as cell sorting or tissue buckling. …”

Distinct mechanisms underlie pattern formation in the skin and skin appendages by Widelitz, R, Baker, R, Plikus, M, Lin, C, Maini, P, Paus, R, Chuong, C

“…Understanding the different mechanisms that lead to patterns in the skin will help us appreciate their full significance in morphogenesis and medical research. Much remains to be learned about complex pattern formation, if we are to bridge the gap between molecular biology and organism phenotypes.…”

Distinct mechanisms underlie pattern formation in the skin and skin appendages. by Widelitz, R, Baker, R, Plikus, M, Lin, C, Maini, P, Paus, R, Chuong, C

“…Understanding the different mechanisms that lead to patterns in the skin will help us appreciate their full significance in morphogenesis and medical research. Much remains to be learned about complex pattern formation, if we are to bridge the gap between molecular biology and organism phenotypes.…”

Multiscale mechanisms of cell migration during development: theory and experiment. by McLennan, R, Dyson, L, Prather, K, Morrison, J, Baker, R, Maini, P, Kulesa, P

“…Long-distance cell migration is an important feature of embryonic development, adult morphogenesis and cancer, yet the mechanisms that drive subpopulations of cells to distinct targets are poorly understood. …”

Distinct mechanisms underlie pattern formation in the skin and skin appendages by Widelitz, R, Baker, R, Plikus, M, Lin, C, Maini, P, Paus, R, Chuong, C

“…Understanding the different mechanisms that lead to patterns in the skin will help us appreciate their full significance in morphogenesis and medical research. Much remains to be learned about complex pattern formation, if we are to bridge the gap between molecular biology and organism phenotypes. …”

Multiscale mechanisms of cell migration during development: theory and experiment by McLennan, R, Dyson, L, Prather, K, Morrison, J, Baker, R, Maini, P, Kulesa, P

“…Long-distance cell migration is an important feature of embryonic development, adult morphogenesis and cancer, yet the mechanisms that drive subpopulations of cells to distinct targets are poorly understood. …”

Multiscale mechanisms of cell migration during development: Theory and experiment by McLennan, R, Dyson, L, Prather, K, Morrison, J, Baker, R, Maini, P, Kulesa, P

“…Long-distance cell migration is an important feature of embryonic development, adult morphogenesis and cancer, yet the mechanisms that drive subpopulations of cells to distinct targets are poorly understood. …”

Capabilities and limitations of tissue size control through passive mechanical forces by Kursawe, J, Brodskiy, P, Zartman, J, Baker, R, Fletcher, A

“…How these cellular properties are coordinated at the tissue level to ensure developmental robustness remains a mystery; understanding this process requires studying multiple concurrent processes that make up morphogenesis, including the spatial patterning of cell fates and apoptosis, as well as cell intercalations. …”

Numerical analysis of the immersed boundary method for cell-based simulation by Cooper, F, Baker, R, Fletcher, A

“…Finally, we present a simu- lation study of a growing epithelial tissue to demonstrate the applicability of our implementation to relevant biological questions, highlighting several features of the IB method that make it well suited to address certain questions in epithelial morphogenesis.…”

Data-driven approaches to modelling collective cell migration by Martina-Perez, S

“…Collective cell migration is the defining characteristic of many biological events involved in morphogenesis, regeneration, and pathology. This abundance, together with the immense clinical and therapeutic advances that would arise from the ability to control collective migration in specific applications in regenerative medicine and oncology, has led to an enormous increase in the number of studies on collective cell migration. …”