Showing 1 - 6 results of 6 for search '"Spaceflight"', query time: 0.05s Refine Results
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    Overexpression of catalase in mitochondria mitigates changes in hippocampal cytokine expression following simulated microgravity and isolation by Linda Rubinstein, Ann-Sofie Schreurs, Samantha M. Torres, Sonette Steczina, Moniece G. Lowe, Frederico Kiffer, Antiño R. Allen, April E. Ronca, Marianne B. Sowa, Ruth K. Globus, Candice G. T. Tahimic

    Published 2021-07-01
    “…These findings suggest a key role for mitochondrial ROS signaling in neuroinflammatory responses to spaceflight and prolonged bedrest, isolation, and confinement on Earth.…”
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    Mitochondria-Targeted Human Catalase in the Mouse Longevity MCAT Model Mitigates Head-Tilt Bedrest-Induced Neuro-Inflammation in the Hippocampus by Linda Rubinstein, Frederico Kiffer, Stephanie Puukila, Moniece G. Lowe, Brie Goo, Amalia Luthens, Ann-Sofie Schreurs, Samantha M. Torres, Sonette Steczina, Candice G. T. Tahimic, Antiño R. Allen

    Published 2022-11-01
    “…Microgravity (modeled by head-tilt bedrest and hind-limb unloading), experienced during prolonged spaceflight, results in neurological consequences, central nervous system (CNS) dysfunction, and potentially impairment during the performance of critical tasks. …”
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