Ophthalmic infections in children presenting to Angkor Hospital for Children, Siem Reap, Cambodia. by Khauv, P, Turner, P, Soeng, C, Soeng, S, Moore, C, Bousfield, R, Stoesser, N, Emary, K, Thanh, D, Baker, S, Hang, V, van Doorn, H, Day, N, Parry, C

“…BACKGROUND: Ophthalmic infections cause significant morbidity in Cambodian children but aetiologic data are scarce. We investigated the causes of acute eye infections in 54 children presenting to the ophthalmology clinic at Angkor Hospital for Children, Siem Reap between March and October 2012. …”

Burkholderia pseudomallei antibodies in children, Cambodia. by Wuthiekanun, V, Pheaktra, N, Putchhat, H, Sin, L, Sen, B, Kumar, V, Langla, S, Peacock, S, Day, N

“…Antibodies to Burkholderia pseudomallei were detected in 16% of children in Siem Reap, Cambodia. This organism was isolated from 30% of rice paddies in the surrounding vicinity. …”

Artesunate for severe malaria in African children Reply by Dondorp, A, Fanello, C, von Seidlein, L, Day, N, White, N

Artesunate for severe malaria in African children - Authors' reply by Dondorp, A, Fanello, C, Von Seidlein, L, Day, N, White, N

Antimicrobial susceptibility of uropathogens isolated from Cambodian children by Moore, C, Sona, S, Poda, S, Putchhat, H, Kumar, V, Sopheary, S, Stoesser, N, Bousfield, R, Day, N, Parry, C

“…<p>Background: Bacterial resistance to commonly used antimicrobials is an increasing problem in Asia but information concerning the antimicrobial susceptibility of bacteria causing urinary tract infections (UTIs) in children is limited.</p> <p>Methods: This was a 5-year retrospective study of children with suspected UTI attending a paediatric hospital in north-west Cambodia. …”

Clinical features and predictors of diphtheritic cardiomyopathy in Vietnamese children. by Kneen, R, Nguyen, MD, Solomon, T, Pham, N, Parry, C, Nguyen, T, Ha, T, Taylor, A, Vo, T, Nguyen, T, Day, N, White, N

“…RESULTS: Thirteen children had diphtheritic cardiomyopathy on admission, and 19 developed it subsequently. …”

Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria. by Tarning, J, Zongo, I, Somé, F, Rouamba, N, Parikh, S, Rosenthal, P, Hanpithakpong, W, Jongrak, N, Day, N, White, N, Nosten, F, Ouedraogo, J, Lindegardh, N

“…The aim of this study was to describe the pharmacokinetic and pharmacodynamic properties of piperaquine in 236 children with uncomplicated falciparum malaria in Burkina Faso. …”

Population pharmacokinetics and pharmacodynamics of piperaquine in children with uncomplicated falciparum malaria by Tarning, J, Zongo, I, Somé, F, Rouamba, N, Parikh, S, Rosenthal, P, Hanpithakpong, W, Jongrak, N, Day, N, White, N, Nosten, F, Ouedraogo, J, Lindegardh, N

“…The aim of this study was to describe the pharmacokinetic and pharmacodynamic properties of piperaquine in 236 children with uncomplicated falciparum malaria in Burkina Faso. …”

A retrospective analysis of melioidosis in Cambodian children, 2009-2013. by Turner, P, Kloprogge, S, Miliya, T, Soeng, S, Tan, P, Sar, P, Yos, P, Moore, C, Wuthiekanun, V, Limmathurotsakul, D, Turner, C, Day, N, Dance, D

“…There were 39 children with B. pseudomallei bacteraemia: 29 (74.4%) of these had clinical and/or radiological evidence of pneumonia. …”

The aetiologies of central nervous system infections in hospitalised Cambodian children by Turner, P, Suy, K, Tan, L, Sar, P, Miliya, T, Hong, N, Hang, V, Ny, N, Soeng, S, Day, N, van Doorn, H, Turner, C

“…<strong>Methods</strong> We did a one year prospective study of children hospitalised with suspected CNS infection at Angkor Hospital for Children, Siem Reap. …”

Pharmacokinetics of oral and intravenous ofloxacin in children with multidrug-resistant typhoid fever. by Bethell, D, Day, N, Dung, N, McMullin, C, Loan, H, Tam, D, Minh, LT, Linh, N, Dung, N, Vinh, H, MacGowan, A, White, L, White, N

“…The pharmacokinetics of oral and intravenous ofloxacin (7.5 mg.kg of body weight-1 given over 30 min) were studied in an open crossover study of 17 Vietnamese children, aged between 5 and 14 years, with acute uncomplicated typhoid fever. …”

Fatal cerebral malaria: distinct microvascular pathologies in children and adult patients. by Wassmer, S, Medana, I, Turner, G, Mai, N, Day, N, Hien, T, White, N, Taylor, T, Molyneux, M, Grau, G

Pharmacokinetics of oral artesunate in children with moderately severe Plasmodium falciparum malaria. by Bethell, D, Teja-Isavadharm, P, Cao, X, Pham, T, Ta, T, Tran, T, Nguyen, T, Pham, T, Kyle, D, Day, N, White, N

“…The pharmacokinetic properties of oral artesunate (3 mg/kg) were determined in 10 Vietnamese children, aged from 6 to 15 years, with acute falciparum malaria of moderate severity. …”

Clinical characteristics and outcome of children hospitalized with scrub typhus in an area of endemicity by Wangrangsimakul, T, Greer, R, Chanta, C, Nedsuwan, S, Blacksell, S, Day, N, Paris, D

“…<p><strong>Background</strong> Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics.</p> <p><strong>Methods</strong> We recruited 60 febrile pediatric patients with a positive scrub typhus rapid diagnostic test result and 40 healthy controls from Chiang Rai Province in northern Thailand. …”

Changing patterns of gastrointestinal parasite infections in Cambodian children: 2006-2011. by Moore, C, Hor, P, Soeng, S, Sun, S, Lee, S, Parry, C, Day, N, Stoesser, N

“…We studied gastrointestinal parasites in symptomatic Cambodian children attending a provincial hospital in Siem Reap, Cambodia between 2006 and 2011. …”

Comparative trial of short-course ofloxacin for uncomplicated typhoid fever in Vietnamese children. by Vinh, H, Duong, N, Phuong, LT, Truong, N, Bay, P, Wain, J, Diep, T, Ho, V, White, N, Day, N, Parry, C

“…An open, randomised comparison of 2 or 3 days of oral ofloxacin (10 mg/kg/day) for uncomplicated typhoid fever was conducted in 235 Vietnamese children. Multi-drug-resistant Salmonella typhi was isolated from 182/202 (90%) children and 5/166 (3%) tested isolates were nalidixic acid-resistant (Na(R)). …”

Antimicrobial resistance in invasive bacterial infections in hospitalized children, Cambodia, 2007–2016 by Fox-Lewis, A, Takata, J, Miliya, T, Lubell, Y, Soeng, S, Sar, P, Rith, K, McKellar, G, Wuthiekanun, V, McGonagle, E, Stoesser, N, Moore, C, Parry, C, Turner, C, Day, N, Cooper, B, Turner, P

“…To determine trends, mortality rates, and costs of antimicrobial resistance in invasive bacterial infections in hospitalized children, we analyzed data from Angkor Hospital for Children, Siem Reap, Cambodia, for 2007–2016. …”

Molecular epidemiology of Group A Streptococcus infections in Cambodian children, 2007-2012. by Turner, P, Ngeth, P, Turner, C, Sao, S, Day, N, Baker, C, Steer, A, Smeesters, P

Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. by Medana, I, Day, N, Salahifar-Sabet, H, Stocker, R, Smythe, G, Bwanaisa, L, Njobvu, A, Kayira, K, Turner, G, Taylor, T, Hunt, N

“…Compared with Vietnamese adults with malaria, Malawian children with malaria had higher concentrations of KA. …”

Surveillance of healthcare-associated infection at Angkor Hospital for Children, Siem Reap, Cambodia by Khun, P, Seng, S, Emary, K, Moore, C, Soeng, S, Ngoun, C, Kumar, V, Day, N, Parry, C, Stoesser, N