Comparison of visual diagnostic accuracy of dermatologists practicing in Germany in patients with light skin and skin of color by Frederik Krefting, Maurice Moelleken, Stefanie Hölsken, Jan-Malte Placke, Robin Tamara Eisenburger, Lea Jessica Albrecht, Alpaslan Tasdogan, Dirk Schadendorf, Selma Ugurel, Joachim Dissemond, Wiebke Sondermann

Get full text

Genetic and Clinical Characteristics of <i>ARID1A</i> Mutated Melanoma Reveal High Tumor Mutational Load without Implications on Patient Survival by Carl Maximilian Thielmann, Johanna Matull, Sebastian Roth, Jan-Malte Placke, Eleftheria Chorti, Anne Zaremba, Georg Lodde, Philipp Jansen, Frederik Krefting, Julia Kretz, Inga Möller, Antje Sucker, Annette Paschen, Elisabeth Livingstone, Lisa Zimmer, Selma Ugurel, Dirk Schadendorf, Eva Hadaschik, Klaus G. Griewank

Get full text

Reduced Staphylococcus Abundance Characterizes the Lesional Microbiome of Actinic Keratosis Patients after Field-Directed Therapies by Jan Kehrmann, Fiona Koch, Skrollan Zumdick, Anna Höwner, Lara Best, Lars Masshöfer, Sarah Scharfenberg, Michael Zeschnigk, Jürgen C. Becker, Dirk Schadendorf, Jan Buer, Alexander Roesch

Get full text

Prognostic factors in the primary care of patients with Merkel cell carcinoma: A monocentric cohort study of 108 patients from a tertiary referral centre by Jan‐Malte Placke, Maximilian Zahn, Hannah Zillikens, Frederik Krefting, Georg C. Lodde, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Antje Sucker, Alexander Roesch, Alpaslan Tasdogan, Nalini K. Srinivas, Dirk Schadendorf, Jürgen C. Becker, Selma Ugurel

“…Methods This noninterventional study investigated a monocentre real‐world patient cohort with a histologically confirmed diagnosis of MCC who presented at the skin cancer centre, University Hospital Essen. Patient and tumour characteristics (age, sex, primary localization, Merkel cell polyomavirus [MCPyV], tumour stage at initial diagnosis and primary treatment measures [surgery, radiation]) were correlated with the patient outcome in terms of recurrence‐free survival (RFS) and overall survival (OS). …”
Get full text

Drivers and barriers of patients’ acceptance of video consultation in cancer care by Angelina Nurtsch, Martin Teufel, Lisa Maria Jahre, André Esber, Raya Rausch, Mitra Tewes, Christoph Schöbel, Stefan Palm, Martin Schuler, Dirk Schadendorf, Eva-Maria Skoda, Alexander Bäuerle

Get full text

ECG Changes in Melanoma Patients Undergoing Cancer Therapy—Data from the ECoR Registry by Julia Pohl, Raluca-Ileana Mincu, Simone Maria Mrotzek, Lena Hinrichs, Lars Michel, Elisabeth Livingstone, Lisa Zimmer, Reza Wakili, Dirk Schadendorf, Tienush Rassaf, Matthias Totzeck

Get full text

The Prognostic Relevance of PMCA4 Expression in Melanoma: Gender Specificity and Implications for Immune Checkpoint Inhibition by Luca Hegedüs, Elisabeth Livingstone, Ágnes Bánkfalvi, Jan Viehof, Ágnes Enyedi, Ágnes Bilecz, Balázs Győrffy, Marcell Baranyi, Anna-Mária Tőkés, Jeovanis Gil, György Marko-Varga, Klaus G. Griewank, Lisa Zimmer, Renáta Váraljai, Antje Sucker, Anne Zaremba, Dirk Schadendorf, Clemens Aigner, Balázs Hegedüs

Get full text

Frequent Occurrence of <i>NRAS</i> and <i>BRAF</i> Mutations in Human Acral Naevi by Philipp Jansen, Ioana Cosgarea, Rajmohan Murali, Inga Möller, Antje Sucker, Cindy Franklin, Annette Paschen, Anne Zaremba, Titus J. Brinker, Ingo Stoffels, Dirk Schadendorf, Joachim Klode, Eva Hadaschik, Klaus G. Griewank

Get full text

Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions by Anne Zaremba, Philipp Jansen, Rajmohan Murali, Anand Mayakonda, Anna Riedel, Dieter Krahl, Hans Burkhardt, Stefan John, Cyrill Géraud, Manuel Philip, Julia Kretz, Inga Möller, Nadine Stadtler, Antje Sucker, Annette Paschen, Selma Ugurel, Lisa Zimmer, Elisabeth Livingstone, Susanne Horn, Christoph Plass, Dirk Schadendorf, Eva Hadaschik, Pavlo Lutsik, Klaus Griewank

Get full text

Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity by Dirk Schadendorf, Antje Sucker, Johannes Koch, Fang Zhao, Susanne Horn, Beatrice Thier, Simone Stupia, Alicia Brüggemann, Nina Schulze, Christoph Coch, Gunther Hartmann, Annette Paschen

Get full text

Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma – analysis of the DeCOG prospective multicenter cohor... by Jan-Malte Placke, Mona Kimmig, Klaus Griewank, Rudolf Herbst, Patrick Terheyden, Jochen Utikal, Claudia Pföhler, Jens Ulrich, Alexander Kreuter, Peter Mohr, Ralf Gutzmer, Friedegund Meier, Edgar Dippel, Julia Welzel, Daniel Robert Engel, Sophia Kreft, Antje Sucker, Georg Lodde, Frederik Krefting, Ingo Stoffels, Joachim Klode, Alexander Roesch, Lisa Zimmer, Elisabeth Livingstone, Eva Hadaschik, Jürgen C. Becker, Michael Weichenthal, Alpaslan Tasdogan, Dirk Schadendorf, Selma Ugurel

Get full text

COVID-19 vaccination in psoriasis patients receiving systemic treatment: A prospective single-center study by Georg Christian Lodde, Frederik Krefting, Jan-Malte Placke, Lea Schneider, Melanie Fiedler, Ulf Dittmer, Jürgen Christian Becker, Jürgen Christian Becker, Jürgen Christian Becker, Stefanie Hölsken, Dirk Schadendorf, Dirk Schadendorf, Selma Ugurel, Selma Ugurel, Wiebke Sondermann

Get full text

Integrative Genomic Analyses of Patient-Matched Intracranial and Extracranial Metastases Reveal a Novel Brain-Specific Landscape of Genetic Variants in Driver Genes of Malignant Me... by Renáta Váraljai, Susanne Horn, Antje Sucker, Daniela Piercianek, Verena Schmitt, Alexander Carpinteiro, Katrin Anne Becker, Julia Reifenberger, Alexander Roesch, Jörg Felsberg, Guido Reifenberger, Ulrich Sure, Dirk Schadendorf, Iris Helfrich

Get full text

Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotype by Lea Jessica Albrecht, Anna Höwner, Klaus Griewank, Smiths S. Lueong, Nils vonNeuhoff, Peter A. Horn, Antje Sucker, Annette Paschen, Elisabeth Livingstone, Selma Ugurel, Lisa Zimmer, Susanne Horn, Jens T. Siveke, Dirk Schadendorf, Renáta Váraljai, Alexander Roesch

Get full text

Allosteric and ATP-Competitive MEK-Inhibition in a Novel Spitzoid Melanoma Model with a RAF- and Phosphorylation-Independent Mutation by Luca Hegedüs, Özlem Okumus, Elisabeth Livingstone, Marcell Baranyi, Ildikó Kovács, Balázs Döme, József Tóvári, Ágnes Bánkfalvi, Dirk Schadendorf, Clemens Aigner, Balázs Hegedüs

Get full text

Factors Influencing the Adjuvant Therapy Decision: Results of a Real-World Multicenter Data Analysis of 904 Melanoma Patients by Georg Lodde, Andrea Forschner, Jessica Hassel, Lena M. Wulfken, Friedegund Meier, Peter Mohr, Katharina Kähler, Bastian Schilling, Carmen Loquai, Carola Berking, Svea Hüning, Kerstin Schatton, Christoffer Gebhardt, Julia Eckardt, Ralf Gutzmer, Lydia Reinhardt, Valerie Glutsch, Ulrike Nikfarjam, Michael Erdmann, Andreas Stang, Bernd Kowall, Alexander Roesch, Selma Ugurel, Lisa Zimmer, Dirk Schadendorf, Elisabeth Livingstone

Get full text

Validating Automatic Concept-Based Explanations for AI-Based Digital Histopathology by Daniel Sauter, Georg Lodde, Felix Nensa, Dirk Schadendorf, Elisabeth Livingstone, Markus Kukuk

Get full text

A Systematic Comparison of Task Adaptation Techniques for Digital Histopathology by Daniel Sauter, Georg Lodde, Felix Nensa, Dirk Schadendorf, Elisabeth Livingstone, Markus Kukuk

Get full text

Proteasome inhibition potentiates Kv1.3 potassium channel expression as therapeutic target in drug-sensitive and -resistant human melanoma cells by Clemens Cammann, Jonas Kulla, Lüder Wiebusch, Christian Walz, Fang Zhao, Theresa Lowinus, Eylin Topfstedt, Neha Mishra, Petra Henklein, Ursula Bommhardt, Lukas Bossaller, Christian Hagemeier, Dirk Schadendorf, Boris Schmidt, Annette Paschen, Ulrike Seifert

Get full text

Evaluation of a Deep Learning Approach to Differentiate Bowen’s Disease and Seborrheic Keratosis by Philipp Jansen, Daniel Otero Baguer, Nicole Duschner, Jean Le’Clerc Arrastia, Maximilian Schmidt, Bettina Wiepjes, Dirk Schadendorf, Eva Hadaschik, Peter Maass, Jörg Schaller, Klaus Georg Griewank

Get full text