Preparation and characterization of 6-mercaptopurine-coated magnetite nanoparticles as a drug delivery system by Dorniani, Dena, Hussein, Mohd. Zobir, Kura, Aminu Umar, Fakurazi, Sharida, Shaari, Abdul Halim, Ahmad, Zalinah

“…The release of 6-mercaptopurine from the FCMP nanocomposite was found to be sustained and governed by pseudo-second order kinetics. …”
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Cytotoxic profiles of a nanodrug delivery based on 6-mercaptopurine-coated magnetite-peg nanoparticles towards leukemia (WEHI-3B) cell lines by Dorniani, Dena, Kura, Aminu Umar, Fakurazi, Sharida, Hussein, Mohd Zobir

“…A drug active, 6-mercaptopurine (MP) was coated on the surface of Fe3O4-PEG nanoparticles using co-precipitation method in order to form a new magnetic nanocomposite (FPEGMP). …”
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Release behavior and toxicity profiles towards leukemia (WEHI-3B) cell lines 6-mercaptopurine-PEG-coated magnetite nanoparticles delivery systems by Dorniani, Dena, Kura, Aminu Umar, Hussein-Al-Ali, Samer Hasan, Hussein, Mohd Zobir, Fakurazi, Sharida, Shaari, Abdul Halim, Ahmad, Zalinah

“…The coating of an active drug, 6-mercaptopurine, into the iron oxide nanoparticles-polyethylene glycol (FNPs-PEG) in order to form a new nanocomposite, FPEGMP-2, was accomplished using coprecipitation technique. …”

Development of anti-cancer and anti-hypertensive nanodelivery systems using magnetite iron oxide-polymeric nanoparticles by Dorniani, Dena

“…This may be attributed to the differences in the percentage of 6-mercaptopurine between the two nanocomposites. Also, MP which is loaded into the surface of FNPs-chitosan compared to FNPs-PEG nanocarrier with the same molar ratio, shows better cytotoxicity effect which is due to the role of chitosan. …”
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