Shmoos, rafts, and uropods- the many facets of cell polarity. by Dustin, M

Synaptic asymmetry to go. by Dustin, M

“…Cell polarity is critical for T lymphocyte movement during their hunt for antigen-bearing cells and for infected target cells. …”

The immunological synapse. by Bromley, S, Burack, W, Johnson, K, Somersalo, K, Sims, T, Sumen, C, Davis, M, Shaw, A, Allen, P, Dustin, M

“…In this review we focus on the concept of immunological synapse formation as it relates to membrane structure, T cell polarity, signaling pathways, and the antigen-presenting cell. …”

Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse. by Vasiliver-Shamis, G, Cho, M, Hioe, C, Dustin, M

“…Cell-to-cell transmission of human immunodeficiency virus type 1 (HIV-1) occurs via a virological synapse (VS), a tight cell-cell junction formed between HIV-infected cells and target cells in which the HIV-1-infected cell polarizes and releases virions toward the noninfected target cell in a gp120- and intercellular adhesion molecule 1 (ICAM-1)-dependent process. …”

Small GTPases and LFA-1 reciprocally modulate adhesion and signaling. by Mor, A, Dustin, M, Philips, MR

“…Inside-out signaling flows through Rap1 to regulator of adhesion and cell polarization enriched in lymphoid tissues (RAPL) and Rap1-GTP interacting adapter molecule (RIAM) that act in conjunction with the cytoskeleton on the cytosolic domain of LFA-1 to increase adhesion of the ectodomain. …”