Comparative Analysis of Alpha-1 Orthosteric-Site Binding by a Clade of Central American Pit Vipers (Genera <i>Atropoides, Cerrophidion, Metlapilcoatlus</i>, and <i>Porthidium</i>) by Lee Jones, Callum Waite, Edgar Neri-Castro, Bryan G. Fry

“…We report potent alpha-1 orthosteric site binding in venoms from <i>Atropoides picadoi</i>, <i>Metlapilcoatlus occiduus</i>, <i>M. olmec</i>, <i>M. mexicanus</i>, <i>M. nummifer</i>. …”
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Differential Antivenom and Small-Molecule Inhibition of Novel Coagulotoxic Variations in <i>Atropoides, Cerrophidion, Metlapilcoatlus,</i> and <i>Porthidium</i> American Viperid Sn... by Lee Jones, Nicholas J. Youngman, Edgar Neri-Castro, Alid Guadarrama-Martínez, Matthew R. Lewin, Rebecca Carter, Nathaniel Frank, Bryan G. Fry

“…Pseudo-procoagulant activity (i.e., thrombin-like), characterized by the direct cleavage of fibrinogen to form weak fibrin clots, was evident for <i>Atropoides picadoi, Cerrophidion</i><i>tzotzilorum</i>, <i>Metlapilcoatlus mexicanus, M. nummifer, M. occiduus, M. olmec</i>, and <i>Porthidium porrasi.</i> In contrast, other venoms cleaved fibrinogen in a destructive (non-clotting) manner, with <i>C. godmani</i> and <i>C. wilsoni</i> being the most potent. …”
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