Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations. by Liu, J, Zhou, Z, Hodgkinson, C, Yuan, Q, Shen, P, Mulligan, C, Wang, A, Gray, R, Roy, A, Virkkunen, M, Goldman, D, Enoch, M

“…The ADH4 SNP rs3762894 was associated with AD in Plains Indians. CONCLUSIONS: The systematic evaluation of alcohol-metabolizing genes in four non-East Asian populations has shown only modest associations with AD, largely for ALDH1A1 and ADH4. …”