Luxembourg Parkinson’s study -comprehensive baseline analysis of Parkinson’s disease and atypical parkinsonism by Lukas Pavelka, Lukas Pavelka, Lukas Pavelka, Rajesh Rawal, Soumyabrata Ghosh, Claire Pauly, Claire Pauly, Claire Pauly, Laure Pauly, Laure Pauly, Laure Pauly, Laure Pauly, Anne-Marie Hanff, Anne-Marie Hanff, Anne-Marie Hanff, Pierre Luc Kolber, Pierre Luc Kolber, Sonja R. Jónsdóttir, Sonja R. Jónsdóttir, Sonja R. Jónsdóttir, Deborah Mcintyre, Deborah Mcintyre, Kheira Azaiz, Kheira Azaiz, Elodie Thiry, Elodie Thiry, Liliana Vilasboas, Liliana Vilasboas, Ekaterina Soboleva, Ekaterina Soboleva, Marijus Giraitis, Olena Tsurkalenko, Stefano Sapienza, Nico Diederich, Jochen Klucken, Enrico Glaab, Gloria A. Aguayo, Eduardo Rosales Jubal, Magali Perquin, Michel Vaillant, Patrick May, Manon Gantenbein, Venkata P. Satagopam, Rejko Krüger, Rejko Krüger, Rejko Krüger, on behalf of the NCER-PD Consortium

“…Alcohol abstinence was significantly higher in PD than controls (17.6 vs. 12.9%, p = 0.003).ConclusionLuxembourg Parkinson’s study constitutes a valuable resource to strengthen the understanding of complex traits in the aforementioned neurodegenerative disorders. …”
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Comparison of two protocols for the generation of iPSC-derived human astrocytes by Patrycja Mulica, Carmen Venegas, Zied Landoulsi, Katja Badanjak, Sylvie Delcambre, Maria Tziortziou, Soraya Hezzaz, Jenny Ghelfi, Semra Smajic, Jens Schwamborn, Rejko Krüger, Paul Antony, Patrick May, Enrico Glaab, Anne Grünewald, Sandro L. Pereira

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Impaired neuron differentiation in GBA-associated Parkinson’s disease is linked to cell cycle defects in organoids by Isabel Rosety, Alise Zagare, Claudia Saraiva, Sarah Nickels, Paul Antony, Catarina Almeida, Enrico Glaab, Rashi Halder, Sergiy Velychko, Thomas Rauen, Hans R. Schöler, Silvia Bolognin, Thomas Sauter, Javier Jarazo, Rejko Krüger, Jens C. Schwamborn

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Transcriptomic analyses of primary astrocytes under TNFα treatment by Cindy Birck, Eric Koncina, Tony Heurtaux, Enrico Glaab, Alessandro Michelucci, Paul Heuschling, Luc Grandbarbe

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Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations by Muhammad Ali, Pierre Garcia, Laetitia P. Lunkes, Alessia Sciortino, Melanie Thomas, Tony Heurtaux, Kamil Grzyb, Rashi Halder, Djalil Coowar, Alex Skupin, Luc Buée, David Blum, Manuel Buttini, Enrico Glaab

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Omics data integration suggests a potential idiopathic Parkinson’s disease signature by Alise Zagare, German Preciat, Sarah. L. Nickels, Xi Luo, Anna S. Monzel, Gemma Gomez-Giro, Graham Robertson, Christian Jaeger, Jafar Sharif, Haruhiko Koseki, Nico J. Diederich, Enrico Glaab, Ronan M. T. Fleming, Jens C. Schwamborn

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Non-Coding RNAs in the Brain-Heart Axis: The Case of Parkinson’s Disease by Shubhra Acharya, Antonio Salgado-Somoza, Francesca Maria Stefanizzi, Andrew I. Lumley, Lu Zhang, Enrico Glaab, Patrick May, Yvan Devaux

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Comprehensive blood metabolomics profiling of Parkinson’s disease reveals coordinated alterations in xanthine metabolism by Elisa Gómez de Lope, Rebecca Ting Jiin Loo, Armin Rauschenberger, Muhammad Ali, Lukas Pavelka, Tainá M. Marques, Clarissa P. C. Gomes, Rejko Krüger, Enrico Glaab, On behalf of the NCER-PD Consortium

“…Here, we report results from a cohort-wide blood plasma metabolic profiling of PD patients and controls in the Luxembourg Parkinson’s Study to detect disease-associated alterations at the level of systemic cellular process and network alterations. …”
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COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms by Marek Ostaszewski, Anna Niarakis, Alexander Mazein, Inna Kuperstein, Robert Phair, Aurelio Orta‐Resendiz, Vidisha Singh, Sara Sadat Aghamiri, Marcio Luis Acencio, Enrico Glaab, Andreas Ruepp, Gisela Fobo, Corinna Montrone, Barbara Brauner, Goar Frishman, Luis Cristóbal Monraz Gómez, Julia Somers, Matti Hoch, Shailendra Kumar Gupta, Julia Scheel, Hanna Borlinghaus, Tobias Czauderna, Falk Schreiber, Arnau Montagud, Miguel Ponce de Leon, Akira Funahashi, Yusuke Hiki, Noriko Hiroi, Takahiro G Yamada, Andreas Dräger, Alina Renz, Muhammad Naveez, Zsolt Bocskei, Francesco Messina, Daniela Börnigen, Liam Fergusson, Marta Conti, Marius Rameil, Vanessa Nakonecnij, Jakob Vanhoefer, Leonard Schmiester, Muying Wang, Emily E Ackerman, Jason E Shoemaker, Jeremy Zucker, Kristie Oxford, Jeremy Teuton, Ebru Kocakaya, Gökçe Yağmur Summak, Kristina Hanspers, Martina Kutmon, Susan Coort, Lars Eijssen, Friederike Ehrhart, Devasahayam Arokia Balaya Rex, Denise Slenter, Marvin Martens, Nhung Pham, Robin Haw, Bijay Jassal, Lisa Matthews, Marija Orlic‐Milacic, Andrea Senff-Ribeiro, Karen Rothfels, Veronica Shamovsky, Ralf Stephan, Cristoffer Sevilla, Thawfeek Varusai, Jean‐Marie Ravel, Rupsha Fraser, Vera Ortseifen, Silvia Marchesi, Piotr Gawron, Ewa Smula, Laurent Heirendt, Venkata Satagopam, Guanming Wu, Anders Riutta, Martin Golebiewski, Stuart Owen, Carole Goble, Xiaoming Hu, Rupert W Overall, Dieter Maier, Angela Bauch, Benjamin M Gyori, John A Bachman, Carlos Vega, Valentin Grouès, Miguel Vazquez, Pablo Porras, Luana Licata, Marta Iannuccelli, Francesca Sacco, Anastasia Nesterova, Anton Yuryev, Anita de Waard, Denes Turei, Augustin Luna, Ozgun Babur, Sylvain Soliman, Alberto Valdeolivas, Marina Esteban‐Medina, Maria Peña‐Chilet, Kinza Rian, Tomáš Helikar, Bhanwar Lal Puniya, Dezso Modos, Agatha Treveil, Marton Olbei, Bertrand De Meulder, Stephane Ballereau, Aurélien Dugourd, Aurélien Naldi, Vincent Noël, Laurence Calzone, Chris Sander, Emek Demir, Tamas Korcsmaros, Tom C Freeman, Franck Augé, Jacques S Beckmann, Jan Hasenauer, Olaf Wolkenhauer, Egon L Willighagen, Alexander R Pico, Chris T Evelo, Marc E Gillespie, Lincoln D Stein, Henning Hermjakob, Peter D'Eustachio, Julio Saez‐Rodriguez, Joaquin Dopazo, Alfonso Valencia, Hiroaki Kitano, Emmanuel Barillot, Charles Auffray, Rudi Balling, Reinhard Schneider, the COVID‐19 Disease Map Community

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Systems level analysis of sex-dependent gene expression changes in Parkinson’s disease by Léon-Charles Tranchevent, Rashi Halder, Enrico Glaab

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RvD1_{n-3 DPA} Downregulates the Transcription of Pro-Inflammatory Genes in Oral Epithelial Cells and Reverses Nuclear Translocation of Transcription Factor p65 after TNF-α... by Maria G. Balta, Olav Schreurs, Rashi Halder, Thomas M. Küntziger, Frank Saetre, Inger Johanne S. Blix, Espen S. Baekkevold, Enrico Glaab, Karl Schenck

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Crowdsourcing digital health measures to predict Parkinson’s disease severity: the Parkinson’s Disease Digital Biomarker DREAM Challenge by Solveig K. Sieberts, Jennifer Schaff, Marlena Duda, Bálint Ármin Pataki, Ming Sun, Phil Snyder, Jean-Francois Daneault, Federico Parisi, Gianluca Costante, Udi Rubin, Peter Banda, Yooree Chae, Elias Chaibub Neto, E. Ray Dorsey, Zafer Aydın, Aipeng Chen, Laura L. Elo, Carlos Espino, Enrico Glaab, Ethan Goan, Fatemeh Noushin Golabchi, Yasin Görmez, Maria K. Jaakkola, Jitendra Jonnagaddala, Riku Klén, Dongmei Li, Christian McDaniel, Dimitri Perrin, Thanneer M. Perumal, Nastaran Mohammadian Rad, Erin Rainaldi, Stefano Sapienza, Patrick Schwab, Nikolai Shokhirev, Mikko S. Venäläinen, Gloria Vergara-Diaz, Yuqian Zhang, the Parkinson’s Disease Digital Biomarker Challenge Consortium, Yuanjia Wang, Yuanfang Guan, Daniela Brunner, Paolo Bonato, Lara M. Mangravite, Larsson Omberg

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Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge by Lusine Khachatryan, Yang Xiang, Artem Ivanov, Enrico Glaab, Garrett Graham, Ilaria Granata, Maurizio Giordano, Lucia Maddalena, Marina Piccirillo, Ichcha Manipur, Giacomo Baruzzo, Marco Cappellato, Batiste Avot, Adrian Stan, James Battey, Giuseppe Lo Sasso, Stephanie Boue, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng, Laurent Falquet, Barbara Di Camillo, Mario R. Guarracino, Vladimir Ulyantsev, Nicolas Sierro, Carine Poussin

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