Serology of typhoid fever in an area of endemicity and its relevance to diagnosis. by House, D, Wain, J, Ho, V, Diep, T, Chinh, N, Bay, P, Vinh, H, Duc, M, Parry, C, Dougan, G, White, N, Hien, T, Farrar, J

“…In this study, the serum antibody responses to the LPS and flagellum antigens of serotype Typhi were investigated with individuals from a region of Vietnam in which typhoid is endemic, and their usefulness for the diagnosis of typhoid fever was evaluated. …”

Prevalence and molecular basis of alpha-thalassaemia in a malaria endemic region of Vietnam by Nguyen, N, O'Riordan, S, Cao, Q, Dao, M, Le, T, Do, Q, Miles, K, Allen, A, Vu, T, Nguyen, H, Dunstan, S, Peto, T, Tran, T, Farrar, J, Clegg, J, Weatherall, D, Nguyen, Q

Endemic norovirus infections in children, Ho Chi Minh City, Vietnam, 2009-2010. by My, P, Thompson, C, Phuc, H, Tuyet, P, Vinh, H, Hoang, N, Minh, P, Vinh, N, Thuy, C, Nga, T, Hau, N, Campbell, J, Chinh, N, Thuong, T, Tuan, H, Farrar, J, Baker, S

Endemic dengue associated with the co-circulation of multiple viral lineages and localized density-dependent transmission. by Raghwani, J, Rambaut, A, Holmes, E, Hang, V, Hien, T, Farrar, J, Wills, B, Lennon, N, Birren, B, Henn, MR, Simmons, C

“…Despite this widespread dispersal, the determinants of dengue transmission in endemic populations are not well understood, although essential for virus control. …”

Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission by Baker, S, Holt, K, Clements, A, Karkey, A, Arjyal, A, Boni, M, Dongol, S, Hammond, N, Koirala, S, Duy, P, Nga, T, Campbell, J, Dolecek, C, Basnyat, B, Dougan, G, Farrar, J

Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission. by Baker, S, Holt, K, Clements, A, Karkey, A, Arjyal, A, Boni, M, Dongol, S, Hammond, N, Koirala, S, Duy, P, Nga, T, Campbell, J, Dolecek, C, Basnyat, B, Dougan, G, Farrar, J

K13-propeller mutations in Plasmodium falciparum populations in malaria endemic regions of Vietnam from 2009 to 2016 by Thuy-Nhien, N, Tuyen, N, Tong, N, Vy, T, Thanh, N, Van, H, Huong-Thu, P, Quang, H, Boni, M, Dolecek, C, Farrar, J, Thwaites, G, Miotto, O, White, N, Tinh Hien, T

Antibodies to the Vi capsule of Salmonella Typhi in the serum of typhoid patients and healthy control subjects from a typhoid endemic region. by House, D, Ho, V, Diep, T, Chinh, N, Bay, P, Vinh, H, Duc, M, Parry, C, Dougan, G, White, N, Farrar, J, Hien, T, Wain, J

“…Typhi during naturally acquired typhoid fever in an endemic area. METHODOLOGY: An indirect ELISA, using tyraminated, purified Vi-CPS, was used to assay anti-Vi-CPS antibodies from typhoid fever cases and controls living in the Ho Chi Minh City and Mekong Delta region of Viet Nam. …”

Differential epidemiology of Salmonella Typhi and Paratyphi A in Kathmandu, Nepal: a matched case control investigation in a highly endemic enteric fever setting by Karkey, A, Thompson, C, Tran Vu Thieu, N, Dongol, S, Le Thi Phuong, T, Voong Vinh, P, Arjyal, A, Martin, L, Rondini, S, Farrar, J, Dolecek, C, Basnyat, B, Baker, S

“…Background Enteric fever, a systemic infection caused by the bacteria Salmonella Typhi and Salmonella Paratyphi A, is endemic in Kathmandu, Nepal. Previous work identified proximity to poor quality water sources as a community-level risk for infection. …”

Neurological complications of dengue virus infection. by Carod-Artal, F, Wichmann, O, Farrar, J, Gascón, J

“…However, overlap of these categories is possible. In endemic countries and after travel to these regions, dengue should be considered in patients presenting with fever and acute neurological manifestations.…”

Temporal fluctuation of multidrug resistant salmonella typhi haplotypes in the mekong river delta region of Vietnam. by Holt, K, Dolecek, C, Chau, T, Duy, P, La, T, Hoang, N, Nga, T, Campbell, J, Manh, B, Vinh Chau, N, Hien, T, Farrar, J, Dougan, G, Baker, S

“…The patterns of disease were consistent with the presence of an endemic haplotype H58-C and a localised outbreak of S. …”

The dynamics of GII.4 Norovirus in Ho Chi Minh City, Vietnam. by Tra My, P, Lam, H, Thompson, C, Phuc, H, Tuyet, P, Vinh, H, Hoang, N, Minh, P, Vinh, N, Thuy, C, Nga, T, Hau, N, Chinh, N, Thuong, T, Tuan, H, Campbell, J, Clements, A, Farrar, J, Boni, M, Baker, S

“…These data show that NoV GII.4 variants are highly endemic in HCMC and describe a scenario of rapid NoV strain replacement occurring in HCMC in early 2010.…”

Temporal fluctuation of multidrug resistant Salmonella Typhi haplotypes in the Mekong River delta region of Vietnam by Holt, K, Dolecek, C, Chau, T, Duy, P, La, T, Hoang, N, Nga, T, Campbell, J, Manh, B, Chau, N, Hien, T, Farrar, J, Dougan, G, Baker, S

“…The patterns of disease were consistent with the presence of an endemic haplotype H58-C and a localised outbreak of S. …”

Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam by Holt, K, McAdam, P, Thai, P, Thuong, N, Ha, D, Lan, N, Lan, N, Nhu, N, Hai, H, Ha, V, Thwaites, G, Edwards, D, Nath, A, Pham, K, Ascher, D, Farrar, J, Khor, C, Teo, Y, Inouye, M, Caws, M, Dunstan, S

“…The data reveal an underlying burden of disease caused by endemic Mtb Lineage 1 associated with activation of long-term latent infection, and a three-fold higher burden associated with more recently introduced Beijing lineage and Lineage 4 Mtb strains. …”

The prevalence and genetic diversity of group A rotaviruses on pig farms in the Mekong Delta region of Vietnam. by Pham, H, Carrique-Mas, J, Nguyen, VC, Ngo, T, Nguyet, L, Do, T, Vo, B, Phan, V, Rabaa, M, Farrar, J, Baker, S, Bryant, J

“…There was no significant association between ARoV infection and clinical disease in pigs, suggesting that endemic asymptomatic circulation of ARoV may complicate rotavirus disease attribution during outbreaks of diarrhea in swine. …”

The prevalence and genetic diversity of group A rotaviruses on pig farms in the Mekong Delta region of Vietnam by Hong Anh, P, Carrique-Mas, J, Van Cuong, N, Hoa, N, Lam Anh, N, Duy, D, Hien, V, Vu Tra My, P, Rabaa, M, Farrar, J, Baker, S, Bryant, J

“…There was no significant association between ARoV infection and clinical disease in pigs, suggesting that endemic asymptomatic circulation of ARoV may complicate rotavirus disease attribution during outbreaks of diarrhea in swine. …”

AIDS-associated Penicillium marneffei infection of the central nervous system. by Le, T, Huu Chi, N, Kim Cuc, N, Manh Sieu, T, Shikuma, C, Farrar, J, Day, J

“…Penicillium marneffei is an important human immunodeficiency virus-associated opportunistic infection endemic in Southeast Asia. Central nervous system infection has not been described. …”

Quantifying the emergence of dengue in Hanoi, Vietnam: 1998-2009 by Cuong, H, Hien, N, Duong, T, Phong, T, Cam, N, Farrar, J, Nam, V, Thai, K, Horby, P

“… BACKGROUND: An estimated 2.4 billion people live in areas at risk of dengue transmission, therefore the factors determining the establishment of endemic dengue in areas where transmission suitability is marginal is of considerable importance. …”

Evolution and adaptation of H5N1 influenza virus in avian and human hosts in Indonesia and Vietnam. by Smith, G, Naipospos, T, Nguyen, T, Jong, d, Vijaykrishna, D, Usman, T, Hassan, S, Nguyen, T, Dao, T, Bui, N, Leung, Y, Cheung, C, Rayner, J, Zhang, J, Zhang, L, Poon, L, Li, K, Nguyen, VC, Hien, T, Farrar, J, Webster, R, Chen, H, Peiris, J, Guan, Y

“…Highly pathogenic avian influenza virus H5N1 is endemic in poultry in East and Southeast Asia with disease outbreaks recently spreading to parts of central Asia, Europe and Africa. …”

Identification of immunogenic salmonella enterica serotype typhi antigens expressed in chronic biliary carriers of S. Typhi in Kathmandu, Nepal by Charles, R, Sultana, T, Alam, M, Yu, Y, Wu-Freeman, Y, Bufano, M, Rollins, S, Tsai, L, Harris, J, Larocque, R, Leung, D, Brooks, W, Nga, T, Dongol, S, Basnyat, B, Calderwood, S, Farrar, J, Khanam, F, Gunn, J, Qadri, F, Baker, S, Ryan, E

“…Typhi antigens that were immunoreactive in carriers, but not in healthy individuals from a typhoid endemic area, were identified. The identified antigens included a number of putative membrane proteins, lipoproteins, and hemolysin-related proteins. …”