The influence of dapagliflozin on cardiac remodeling, myocardial function and metabolomics in type 1 diabetes mellitus rats by Eder Anderson Rodrigues, Camila Moreno Rosa, Dijon Henrique Salome Campos, Felipe Cesar Damatto, Gilson Masahiro Murata, Lidiane Moreira Souza, Luana Urbano Pagan, Mariana Gatto, Jessica Yumi Brosler, Hebreia Oliveira Almeida Souza, Mario Machado Martins, Luciana Machado Bastos, Suzana Erico Tanni, Katashi Okoshi, Marina Politi Okoshi

“…The functional improvement is combined with restored pyruvate kinase and phosphofructokinase activity and attenuated metabolomics changes.…”
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Influence of Isolated Resistance Exercise on Cardiac Remodeling, Myocardial Oxidative Stress, and Metabolism in Infarcted Rats by Eder Anderson Rodrigues, Aline Regina Ruiz Lima, Mariana Janini Gomes, Lidiane Moreira Souza, Thierres Hernani Dias Pontes, Luana Urbano Pagan, Gilson Masahiro Murata, Felipe Cesar Damatto, Igor Carvalho Depra, Amanda Bergamo Gonçalves Castro Rego, David Rafael Abreu Reyes, Leonardo Antonio Mamede Zornoff, Katashi Okoshi, Marina Politi Okoshi

“…Exercise increased the maximum load-carrying capacity, with no changes in cardiac structure or LV function. Myocyte diameters were lower in MI than in Sham and MI-Ex. …”
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Effects of the SGLT2 Inhibition on Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats, a Model of Type 1 Diabetes Mellitus by Camila Moreno Rosa, Dijon Henrique Salome Campos, David Rafael Abreu Reyes, Felipe Cesar Damatto, Lucas Yamada Kurosaki, Luana Urbano Pagan, Mariana Janini Gomes, Camila Renata Corrêa, Ana Angelica Henrique Fernandes, Marina Politi Okoshi, Katashi Okoshi

“…DM echocardiogram presented left ventricular and left atrium dilation with impaired systolic and diastolic function. Cardiac changes were attenuated by dapagliflozin. Myocardial hydroxyproline concentration and interstitial collagen fraction did not differ between groups. …”
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