The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock by Hopwood, TW, Hall, S, Begley, N, Forman, R, Brown, S, Vonslow, R, Saer, B, Little, MC, Murphy, EA, Hurst, RJ, Ray, DW, Macdonald, AS, Brass, A, Bechtold, DA, Gibbs, JE, Loudon, AS, Else, KJ

An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes. by Partridge, F, Brown, A, Buckingham, S, Willis, N, Wynne, G, Forman, R, Else, K, Morrison, A, Matthews, J, Russell, A, Lomas, D, Sattelle, D

“…We have developed an INVertebrate Automated Phenotyping Platform (INVAPP) for high-throughput, plate-based chemical screening, and an algorithm (Paragon) which allows screening for compounds that have an effect on motility and development of parasitic worms. We have validated its utility by determining the efficacy of a panel of known anthelmintics against model and parasitic nematodes: Caenorhabditis elegans, Haemonchus contortus, Teladorsagia circumcincta, and Trichuris muris. …”