Role of cholesterol metabolism in the anticancer pharmacology of selective estrogen receptor modulators by Gómez-Coronado, D, Lasunción, MA, Martínez-Botas, J, Fernandez-Suarez, ME

“…Selective estrogen receptor modulators (SERMs) are a class of compounds that bind to estrogen receptors (ERs) and possess estrogen agonist or antagonist actions in different tissues. …”

Selective estrogen receptor modulators (SERMs) affect cholesterol homeostasis through the master regulators SREBP and LXR by Fernandez-Suarez, ME, Daimiel, L, Villa-Turégano, G, Pavón, MV, Busto, R, Escolà-Gil, JC, Platt, FM, Lasunción, MA, Martínez-Botas, J, Gómez-Coronado, D

“…Selective estrogen receptor modulators (SERMs) are nonsteroidal drugs that display an estrogen‐agonist or estrogen‐antagonist effect depending on the tissue targeted. …”

Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport. by Fernández-Suárez, ME, Escolà-Gil, JC, Pastor, O, Dávalos, A, Blanco-Vaca, F, Lasunción, MA, Martínez-Botas, J, Gómez-Coronado, D

“…Selective estrogen receptor modulators (SERMs) are widely prescribed drugs that alter cellular and whole-body cholesterol homeostasis. …”