Differential Effects of Novel Dopamine Reuptake Inhibitors on Interference With Long-Term Social Memory in Mice by Judith Camats-Perna, Predrag Kalaba, Karl Ebner, Simone B. Sartori, Harish Vuyyuru, Nilima Y. Aher, Vladimir Dragačević, Nicolas Singewald, Mario Engelmann, Mario Engelmann, Gert Lubec

“…Thus, the data from the present study suggests that the DA re-uptake inhibitors tested protect the consolidation of long-term social memory against interference for defined durations after learning. …”
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The Novel Analogue of Modafinil CE-158 Protects Social Memory against Interference and Triggers the Release of Dopamine in the Nucleus Accumbens of Mice by Karl Ebner, Simone B. Sartori, Rita Murau, Fabian Kopel, Predrag Kalaba, Vladimir Dragačević, Johann J. Leban, Nicolas Singewald, Mario Engelmann, Gert Lubec

“…However, when 10 mg/kg of the drug was administered after learning, CE-158 failed to prevent social memory from interference. Paralleling these behavioral effects, the systemic administration of 10 mg/kg CE-158 caused a rapid and sustained elevation of extracellular dopamine in the nucleus accumbens, a brain area where dopaminergic signaling plays a key role in learning and memory function, of freely moving mice, while 1 mg/kg was not sufficient for altering dopamine levels. …”
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