Acute pancreatitis, a protocol for diagnosis and treatment by Berger, P, Mollema, R, Girbes, A, Van Dullemen, H, Bosscha, K, Gooszen, H, Ploeg, R

“…Prognosis on admission can be established using a scoring system such as the modified Glasgow score, the Ranson score and the 'Acute physiology and chronic health evaluation'(APACHE)-II-score. The treatment of acute pancreatitis is primarily conservative. …”

[Acute pancreatitis--a protocol for diagnosis and treatment] by Berger, P, Mollema, R, Girbes, A, van Dullemen, H, Bosscha, K, Gooszen, H, Ploeg, R

“…Prognosis on admission can be established using a scoring system such as the modified Glasgow score, the Ranson score and the 'Acute physiology and chronic health evaluation'--(APACHE)-II-score. The treatment of acute pancreatitis is primarily conservative. …”

Probiotic prophylaxis in patients with predicted severe acute pancreatitis: A randomised, double-blind, placebo-controlled trial by Besselink, M, Van Santvoort, H, Buskens, E, Boermeester, M, Van Goor, H, Timmerman, H, Nieuwenhuijs, V, Bollen, T, Van Ramshorst, B, Witteman, B, Rosman, C, Ploeg, R, Brink, M, Schaapherder, A, Dejong, C, Wahab, P, Van Laarhoven, C, Van Der Harst, E, Van Eijck, G, Cuesta, M, Akkermans, L, Gooszen, H

“…A total of 296 patients with predicted severe acute pancreatitis (APACHE II score ≥ 8, Imrie score ≥ 3 or C-reactive protein concentration > 150 mg/1) were included and randomised to one of two groups. …”

[Probiotic prophylaxis in patients with predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial]. by Besselink, MG, van Santvoort, H, Buskens, E, Boermeester, M, van Goor, H, Timmerman, H, Nieuwenhuijs, V, Bollen, T, van Ramshorst, B, Witteman, B, Rosman, C, Ploeg, R, Brink, M, Schaapherder, A, Dejong, C, Wahab, P, van Laarhoven, C, van der Harst, E, Eijck, v, Cuesta, M, Akkermans, L, Gooszen, H

“…METHOD: A total of 296 patients with predicted severe acute pancreatitis (APACHE II score > or = 8, Imrie score > or = 3 or C-reactive protein concentration > 150 mg/l) were included and randomised to one of two groups. …”

Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial. by Besselink, MG, van Santvoort, H, Buskens, E, Boermeester, M, van Goor, H, Timmerman, H, Nieuwenhuijs, V, Bollen, T, van Ramshorst, B, Witteman, B, Rosman, C, Ploeg, R, Brink, M, Schaapherder, A, Dejong, C, Wahab, P, van Laarhoven, C, van der Harst, E, Eijck, v, Cuesta, M, Akkermans, L, Gooszen, H

“…METHODS: In this multicentre randomised, double-blind, placebo-controlled trial, 298 patients with predicted severe acute pancreatitis (Acute Physiology and Chronic Health Evaluation [APACHE II] score > or =8, Imrie score > or =3, or C-reactive protein >150 mg/L) were randomly assigned within 72 h of onset of symptoms to receive a multispecies probiotic preparation (n=153) or placebo (n=145), administered enterally twice daily for 28 days. …”