Is intraindividual reaction time variability an independent cognitive predictor of mortality in old age? Findings from the Sydney Memory and Ageing Study. by Nicole A Kochan, David Bunce, Sarah Pont, John D Crawford, Henry Brodaty, Perminder S Sachdev

“…This study investigated the association of IIVRT and all-cause mortality while accounting for cognitive level, incident dementia and biomedical risk factors in 861 participants aged 70-90 from the Sydney Memory and Ageing Study. Participants completed two computerised reaction time (RT) tasks (76 trials in total) at baseline, and comprehensive medical and neuropsychological assessments every 2 years. …”
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Association of adherence to the Australian Dietary Guidelines with cognitive performance and cognitive decline in the Sydney Memory and Ageing Study: a longitudinal analysis by Xi Chen, Zhixin Liu, Perminder S. Sachdev, Nicole A. Kochan, Henry Brodaty, Fiona O'Leary

“…We used longitudinal data from the Sydney Memory and Aging Study comprising 1037 community-dwelling non-demented participants aged 70–90 years. …”
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Longitudinal changes in participant and informant reports of subjective cognitive complaints are associated with dementia risk by Katya Numbers, Ben C. P. Lam, John D. Crawford, Nicole A. Kochan, Perminder S. Sachdev, Henry Brodaty

“…Questions remain about participant-reported versus informant-reported SCCs as indicators of future dementia and about longitudinal changes in participant-and informant-reported SCCs and risk of incident dementia.MethodParticipants were 873 older adults (M = 78.65-years; 55% female) and 849 informants from the Sydney Memory and Ageing Study. Comprehensive assessments occurred biennially, and clinical diagnoses were made by expert consensus for 10-years. …”
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Application of generalizability theory to evaluate the Kessler Psychological Distress Scale and distinguish between enduring and dynamic distress by Vivienne Yu-X Yan, Katya Numbers, Perminder S. Sachdev, Henry Brodaty, Oleg N. Medvedev

“…Method: Generalizability theory (G-theory) was applied to differentiate enduring and dynamic distress and examine the reliability of K-10 in a sample of 201 adults (43% males) aged 70 to 90 years old who participated in Sydney Memory and Ageing Study. The data were collected biennially over ten years. …”
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Investigating Olfactory Gene Variation and Odour Identification in Older Adults by Siddharth Raj, Anbupalam Thalamuthu, Nicola J Armstrong, Margaret J Wright, John B Kwok, Julian N Trollor, David Ames, Peter R Schofield, Henry Brodaty, Perminder S Sachdev, Karen A Mather

“…Participants were Caucasian older adults from the Sydney Memory and Ageing Study and the Older Australian Twins Study with genome-wide genotyping data (<i>n</i> = 1395, mean age = 75.52 ± 6.45). …”
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People with mild cognitive impairment are at increased risk of serious injury by Lara Harvey, Barbara Toson, Henry Brodaty, Brian Draper, Nicole Kochan, Perminder Sachdev, Rebecca Mitchell, Jacqueline Close

“…To overcome this limitation, hospitalisation and death data was linked to data from participants (community-dwelling 70-90 year olds) enrolled in the population-based longitudinal Sydney Memory and Ageing Study (MAS). MAS participants underwent comprehensive neuropsychological assessments at baseline, then 2, 4 and 6 years’ follow-up to accurately determine cognitive status at each time-period. …”
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Ensemble feature selection with data-driven thresholding for Alzheimer's disease biomarker discovery by Annette Spooner, Gelareh Mohammadi, Perminder S. Sachdev, Henry Brodaty, Arcot Sowmya, for the Sydney Memory and Ageing Study and the Alzheimer’s Disease Neuroimaging Initiative

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