ROS-producing nanomaterial engineered from Cu(I) complexes with P2N2-ligands for cancer cells treating by Bulat A. Faizullin, Irina R. Dayanova, Alexey V. Kurenkov, Aidar T. Gubaidullin, Alina F. Saifina, Irek R. Nizameev, Kirill V. Kholin, Mikhail N. Khrizanforov, Aisylu R. Sirazieva, Igor A. Litvinov, Alexandra D. Voloshina, Anna P. Lyubina, Guzel V. Sibgatullina, Dmitry V. Samigullin, Elvira I. Musina, Igor D. Strelnik, Andrey A. Karasik, Asiya R. Mustafina

“…The enhanced level of ROS revealed in HuTu 80 cells incubated with the NPs can be associated with the significant level of their mitochondrial localization.…”
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Synthesis and Anticancer Evaluation of Novel 7-Aza-Coumarine-3-Carboxamides by Alexey V. Trifonov, Almir S. Gazizov, Anipa S. Tapalova, Lyudmila K. Kibardina, Nurbol O. Appazov, Alexandra D. Voloshina, Anastasiia S. Sapunova, Anna P. Luybina, Gulmira M. Abyzbekova, Alexey B. Dobrynin, Igor A. Litvinov, Akerke K. Tauekel, Sholpan O. Yespenbetova, Alexander R. Burilov, Michail A. Pudovik

“…The anticancer activity of the most potent 7-aza-coumarine-3-carboxamides against the HuTu 80 cell line is equal to that of reference Doxorubicin, while the selectivity towards the normal cell line is 9–14 fold higher.…”
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Novel Mitochondria-Targeted Amphiphilic Aminophosphonium Salts and Lipids Nanoparticles: Synthesis, Antitumor Activity and Toxicity by Vladimir F. Mironov, Mudaris N. Dimukhametov, Andrey V. Nemtarev, Tatiana N. Pashirova, Olga V. Tsepaeva, Alexandra D. Voloshina, Alexandra B. Vyshtakalyuk, Igor A. Litvinov, Anna P. Lyubina, Anastasiia S. Sapunova, Dinara F. Abramova, Vladimir V. Zobov

“…A high in vitro cytotoxicity of APPs against M-HeLa, HuTu 80, PC3, DU-145, PANC-1, and MCF-7 lines was found. …”
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