Preliminary analysis of the antinociceptive activity of zerumbone by Sulaiman, Mohd Roslan, Perimal, Enoch Kumar, Zakaria, Zainul Amiruddin, Mokhtar, Fuzi, Akhtar, Muhammad Nadim, Lajis, Md Nordin, Israf Ali, Daud Ahmad

Subjects: “…Analgesics…”

Antinociceptive and anti-inflammatory effects of the ethanol extract of Alpinia conchigera rhizomes in various animal models. by Sulaiman, Mohd Roslan, Zakaria, Zainul Amiruddin, Tengku Mohamad, Tengku Azam Shah, Ismail, Maznah, Baharuldin, Mohamad Taufik Hidayat, Israf Ali, Daud Ahmad, Adilius, M.

“…This study evaluated the analgesic and anti-inflammatory activities of the ethanol extract of A. conchigera rhizomes in mice and rats, respectively. …”

Antinociceptive activity of methanolic extract of Acmella uliginosa (Sw.) Cass. by Ong, Hui Ming, Tengku Mohamad, Tengku Azam Shah, Makhtar, Nor ‘Adilah, Khalid, Mohamed Hanief, Khalid, Syamimi, Perimal, Enoch Kumar, Mastuki, Siti Nurulhuda, Zakaria, Zainul Amiruddin, Lajis, Nordin, Israf Ali, Daud Ahmad, Sulaiman, Mohd Roslan

“…Furthermore, the reversal of antinociception of MEAU by naloxone suggests the involvement of opioid system in its centrally mediated analgesic activity. Moreover, MEAU-treated mice did not show any significant motor performance alterations. …”

Anti-hyperalgesic effect of a benzilidine-cyclohexanone analogue on a mouse model of chronic constriction injury-induced neuropathic pain: participation of the κ-opioid receptor an... by Lee, Ming Tatt, Khalivulla, Shaik Ibrahim, Akhtar, Muhammad Nadeem, Lajis, Nordin, Perimal, Enoch Kumar, Omar Farouk, Ahmad Akira, Israf Ali, Daud Ahmad, Sulaiman, Mohd Roslan

“…The present study investigated the analgesic effect of a novel synthetic cyclohexanone derivative, 2,6-bis-4-(hydroxyl-3-methoxybenzilidine)-cyclohexanone or BHMC in a mouse model of chronic constriction injury-induced neuropathic pain. …”

Antinociceptive and anti-inflammatory effects of the ethanol extract of Alpinia conchigera Griff. leaves in various animal models by Sulaiman, Mohd Roslan, Zakaria, Zainul Amiruddin, Adilius, M., Mohamad, Azam Shah, Ismail, Maznah, Israf Ali, Daud Ahmad

“…These findings suggest that EACL presents notable analgesic and anti-inflammatory activities, which support its folkloric use for painful and inflammatory conditions.…”

Evaluation of the antinociceptive activity of Ficus deltoidea aqueous extract. by Sulaiman, Mohd Roslan, Hussain, Mohd. Khairi, Zakaria, Zainul Amiruddin, Somchit, M.N., Moin, Saidi, Tengku Mohamad, Tengku Azam Shah, Israf Ali, Daud Ahmad

“…Furthermore, the antinociceptive effect of the extract in the formalin and hot plate test was reversed by the non-selective opioid receptor antagonist naloxone suggesting that the endogenous opioid system is involved in its analgesic mechanism of action. Thus, the present results demonstrated that F. deltoidea leaves aqueous extract contains pharmacologically active constituents which possess antinociceptive activity justifying its popular therapeutic use in treating conditions associated with the painful conditions.…”

Antinociceptive activity of the essential oil of Zingiber zerumbet. by Sulaiman, Mohd Roslan, Tengku Mohamad, Tengku Azam Shah, Shaik Mossadeq, Wan Mastura, Moin, Saidi, Mohd Yusoff, Mazina, Mokhtar, Ahmad Fauzi, Zakaria, Zainul Amiruddin, Israf Ali, Daud Ahmad, Lajis, Nordin

“…In addition, the antinociceptive effect of the EOZZ in the formalin-induced paw licking test as well as hot-plate test was reversed by the nonselective opioid receptor antagonist, naloxone suggesting that the opioid system was involved in its analgesic mechanism of action. On the basis of these data, we concluded that the EOZZ possessed both central and peripheral antinociceptive activities which justifying its popular folkloric use to relieve some pain conditions. …”

Activity of cardamonin on chemical model of nociception in mice by Chung, Pui Ping, Lee, Ming Tatt, Akhtar, Muhammad Nadeem, Perimal, Enoch Kumar, Omar Farouk, Ahmad Akira, Israf Ali, Daud Ahmad, Sulaiman, Mohd Roslan

“…Thus, there is a demand to search for new pharmacologically potent analgesic compounds with fewer or no adverse effects. …”
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Preliminary study on antinociceptove effect of aqueous extract of Boesenbergia pandurata in formalin-induced nociception test in mice by Ee, Ai Chin, Omar Farouk, Ahmad Akira, Perimal, Enoch Kumar, Israf Ali, Daud Ahmad, Lee, Ming Tatt, Sulaiman, Mohd Roslan

“…Hence, researchers are now focused on traditional herbal research to search for potential analgesic substances that are with minimal or no adverse effects. …”
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Antinociceptive activity of a synthetic chalcone, flavokawin B on chemical and thermal models of nociception in mice by Tengku Mohamad, Tengku Azam Shah, Akhtar, Mohamad Nadeem, Zakaria, Zainul Amiruddin, Perimal, Enoch Kumar, Khalid, Syamimi, P. A. Mohd, Khalid, Mohamed Hanief, Israf Ali, Daud Ahmad, Lajis, Md. Nordin, Sulaiman, Mohd Roslan

“…The present results indicate that FKB produced pronounced antinociception effect against both chemical and thermal models of pain in mice that exhibited both peripheral and central analgesic activity.…”
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Antinociceptive effects of cardamonin in mice: Possible involvement of TRPV1, glutamate and opioid receptors by Chung, Pui Ping, Tengku Mohamad, Tengku Azam Shah, Akhtar, Muhammad Nadeem, Perimal, Enoch Kumar, Akira, Ahmad, Israf Ali, Daud Ahmad, Sulaiman, Mohd Roslan

“…It plays an important role in inflammation and serves as a warning sign to avoid further injury. Analgesics are used to manage pain and provide comfort to patients. …”
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