Functional magnetic resonance imaging. by Matthews, P, Jezzard, P

“…Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is a powerful approach to defining activity in the healthy and diseased human brain. …”

The clinical potential of functional magnetic resonance imaging. by Jezzard, P, Buxton, R

“…Functional magnetic resonance imaging (fMRI) has had a huge impact on understanding the healthy human brain. …”

Dynamic forcing of end-tidal carbon dioxide and oxygen applied to functional magnetic resonance imaging. by Wise, R, Pattinson, K, Bulte, D, Chiarelli, P, Mayhew, S, Balanos, G, O'Connor, D, Pragnell, T, Robbins, P, Tracey, I, Jezzard, P

Simultaneous recording of laser-evoked brain potentials and continuous, high-field functional magnetic resonance imaging in humans. by Iannetti, G, Niazy, R, Wise, R, Jezzard, P, Brooks, J, Zambreanu, L, Vennart, W, Matthews, P, Tracey, I

“…Simultaneous recording of event-related electroencephalographic (EEG) and functional magnetic resonance imaging (fMRI) responses has the potential to provide information on how the human brain reacts to an external stimulus with unique spatial and temporal resolution. …”

Functional asymmetry for auditory processing in human primary auditory cortex. by Devlin, J, Raley, J, Tunbridge, E, Lanary, K, Floyer-Lea, A, Narain, C, Cohen, I, Behrens, T, Jezzard, P, Matthews, P, Moore, DR

“…We tested this hypothesis using functional magnetic resonance imaging to evaluate human auditory cortex responses to monaurally presented tones. …”

Dual regression physiological modeling of resting-state EPI power spectra: Effects of healthy aging by Viessmann, O, Möller, H, Jezzard, P

“…Aging and disease-related changes in the arteriovasculature have been linked to elevated levels of cardiac cycle-induced pulsatility in the cerebral microcirculation. Functional magnetic resonance imaging (fMRI), acquired fast enough to unalias the cardiac frequency contributions, can be used to study these physiological signals in the brain. …”

Evidence for a vascular contribution to diffusion FMRI at high b value. by Miller, K, Bulte, D, Devlin, H, Robson, M, Wise, R, Woolrich, M, Jezzard, P, Behrens, T

“…Recent work has suggested that diffusion-weighted functional magnetic resonance imaging (FMRI) with strong diffusion weighting (high b value) detects neuronal swelling that is directly related to neuronal firing. …”

The cortical organization of audio-visual sentence comprehension: an fMRI study at 4 Tesla. by Capek, C, Bavelier, D, Corina, D, Newman, A, Jezzard, P, Neville, H

“…The current study examines the neural organization of audio-visual (AV) sentence processing using functional magnetic resonance imaging (fMRI) at 4 Tesla. Participants viewed the face and upper body of a speaker via a video screen while listening to her produce, in alternating blocks, English sentences and sentences composed of pronounceable non-words. …”

Methamphetamine activates reward circuitry in drug naive human subjects. by Völlm, B, de Araujo, I, Cowen, P, Rolls, E, Kringelbach, M, Smith, K, Jezzard, P, Heal, R, Matthews, P

“…In this study we use functional magnetic resonance imaging (fMRI) to identify the brain circuitry involved in the psychostimulant effect of methamphetamine in psychostimulant-naïve human subjects. …”

The effect of basal vasodilation on hypercapnic and hypocapnic reactivity measured using magnetic resonance imaging. by Bright, MG, Donahue, M, Duyn, J, Jezzard, P, Bulte, D

“…Using blood oxygenation level-dependent functional magnetic resonance imaging at 3 T, breath holding and cued deep breathing respiratory challenges were administered to assess hypercapnia and hypocapnia reactivity, respectively. …”

Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition. by Rogers, R, Ramnani, N, Mackay, C, Wilson, J, Jezzard, P, Carter, C, Smith, S

“…METHODS: Fourteen healthy volunteers completed an event-based functional magnetic resonance imaging protocol to investigate blood-oxygenation-level-dependent (BOLD) responses during independently modeled phases of choice cognition. …”

Independent anatomical and functional measures of the V1/V2 boundary in human visual cortex. by Bridge, H, Clare, S, Jenkinson, M, Jezzard, P, Parker, A, Matthews, P

“…Functional borders were mapped with functional magnetic resonance imaging (fMRI) using a narrow, vertical black and white contrast-reversing wedge. …”

Visualization of altered neurovascular coupling in chronic stroke patients using multimodal functional MRI by Blicher, J, Blicher, J, Stagg, C, O'Shea, J, Østergaard, L, MacIntosh, B, Johansen-Berg, H, Jezzard, P, Donahue, M, Donahue, M, Donahue, M

“…Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is frequently employed; however, BOLD contrast depends on specific coupling relationships between the cerebral metabolic rate of oxygen (CMRO 2), cerebral blood flow (CBF), and volume (CBV), which may not exist following stroke. …”

Baseline GABA concentration and fMRI response. by Donahue, M, Near, J, Blicher, J, Jezzard, P

“…Coordination between glutamatergic excitatory neurons and gamma-aminobutyric acid (GABA)-ergic inhibitory interneurons is fundamental to the regulation of neuronal firing rates and is believed to have relevance to functional magnetic resonance imaging (fMRI) contrast. While much is known regarding the molecular behavior of excitatory and inhibitory processes, comparatively less is known regarding the role of such processes in explaining variations in fMRI and related hemodynamic imaging metrics. …”

Sources of systematic bias in hypercapnia-calibrated functional MRI estimation of oxygen metabolism. by Chiarelli, P, Bulte, D, Piechnik, S, Jezzard, P

“…The change in cerebral rate of oxidative metabolism (CMR(O(2))) during neural activation may be estimated from blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) and arterial spin-labeling (ASL) fMRI measurements. …”

Visualization of altered neurovascular coupling in chronic stroke patients using multimodal functional MRI. by Blicher, J, Stagg, C, O'Shea, J, Østergaard, L, MacIntosh, B, Johansen-Berg, H, Jezzard, P, Donahue, M

“…Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is frequently employed; however, BOLD contrast depends on specific coupling relationships between the cerebral metabolic rate of oxygen (CMRO(2)), cerebral blood flow (CBF), and volume (CBV), which may not exist following stroke. …”

Cerebral blood flow, blood volume, and oxygen metabolism dynamics in human visual and motor cortex as measured by whole-brain multi-modal magnetic resonance imaging. by Donahue, M, Blicher, J, Østergaard, L, Feinberg, D, MacIntosh, B, Miller, K, Günther, M, Jezzard, P

“…The development of neuroimaging methods to characterize flow-metabolism coupling is crucial for understanding mechanisms that subserve oxygen delivery. Functional magnetic resonance imaging (fMRI) using blood-oxygenation-level-dependent (BOLD) contrast reflects composite changes in cerebral blood volume (CBV), cerebral blood flow (CBF), and the cerebral metabolic rate of oxygen consumption (CMRO(2)). …”

Characterization of regional heterogeneity in cerebrovascular reactivity dynamics using novel hypocapnia task and BOLD fMRI. by Bright, MG, Bulte, D, Jezzard, P, Duyn, J

“…We offer a new method for characterizing the magnitude and dynamics of the vascular response to changes in arterial gas tensions using non-invasive blood oxygenation level-dependent functional magnetic resonance imaging (BOLD fMRI) and paradigms appropriate for clinical settings. …”

Sources of distortion in functional MRI data. by Jezzard, P, Clare, S

“…Functional magnetic resonance image (fMRI) experiments rely on the ability to detect subtle signal changes in magnetic resonance image time series. …”

Quantitative measurement of cerebral physiology using respiratory-calibrated MRI. by Bulte, D, Kelly, M, Germuska, M, Xie, J, Chappell, M, Okell, T, Bright, MG, Jezzard, P

“…Functional magnetic resonance imaging typically measures signal increases arising from changes in the transverse relaxation rate over small regions of the brain and associates these with local changes in cerebral blood flow, blood volume and oxygen metabolism. …”