-
1
A cell-penetrating PHLPP peptide improves cardiac arrest survival in murine and swine models
Published 2023-05-01Subjects: “…Therapeutics…”
Get full text
Article -
2
Biofilm formation: mechanistic insights and therapeutic targets
Published 2023-12-01Subjects: Get full text
Article -
3
Biomaterial-Based Therapeutic Strategies for Obesity and Its Comorbidities
Published 2022-07-01“…Finally, based on the systematic analysis of biomaterial-based obesity therapeutic strategies, the future prospects and challenges in this field are proposed.…”
Get full text
Article -
4
Emerging non-antibody‒drug conjugates (non-ADCs) therapeutics of toxins for cancer treatment
Published 2024-04-01Get full text
Article -
5
Reticulocalbin 2 as a Potential Biomarker and Therapeutic Target for Atherosclerosis
Published 2022-03-01Get full text
Article -
6
Understanding the unique mechanism of ferroptosis: a promising therapeutic target
Published 2024-03-01Get full text
Article -
7
Breakthroughs on the clinical management of headache and questions that need to be solved
Published 2021-12-01Subjects: Get full text
Article -
8
3D Lung Tissue Models for Studies on SARS-CoV-2 Pathophysiology and Therapeutics
Published 2022-09-01Get full text
Article -
9
Two new luminescent coordination polymers: Therapeutic effects on angina pectoris
Published 2022-02-01“…The luminescent properties investigations showed that 1–2 emit intense luminescence with different maximum emission peaks. Their therapeutic and nursing protective effects on angina pectoris were assessed and we also discussed the corresponding mechanism simultaneously. …”
Get full text
Article -
10
Recent advances in ginsenosides against respiratory diseases: Therapeutic targets and potential mechanisms
Published 2023-02-01“…In this review, we summarize the current therapeutic effects and molecular mechanisms of ginsenosides in respiratory diseases. …”
Get full text
Article -
11
Redox Control in Acute Lymphoblastic Leukemia: From Physiology to Pathology and Therapeutic Opportunities
Published 2021-05-01Get full text
Article -
12
A Machine Learning Model to Predict Survival and Therapeutic Responses in Multiple Myeloma
Published 2023-04-01Get full text
Article -
13
Biology of the mRNA Splicing Machinery and Its Dysregulation in Cancer Providing Therapeutic Opportunities
Published 2021-05-01“…In addition, we review investigations to discover therapeutic targets in the spliceosome and give an overview of inhibitors and modulators of the mRNA splicing process identified so far. …”
Get full text
Article -
14
The cellular composition of the tumor microenvironment is an important marker for predicting therapeutic efficacy in breast cancer
Published 2024-02-01“…During the treatment of breast cancer, different cells have different influences on the therapeutic response. And after treatment, the cellular composition in the tumor microenvironment will change too. …”
Get full text
Article -
15
Chronic Pain after Bone Fracture: Current Insights into Molecular Mechanisms and Therapeutic Strategies
Published 2022-08-01“…We also review the mechanisms of action of analgesics in the clinic and their side effects as well as promising therapeutic candidates (e.g., specialized pro-resolving mediators, a caspase-6 inhibitor, and a STING agonist) for pain relief by the attenuation of neuroinflammation with the aim of better managing patients undergoing CFP in the clinical setting.…”
Get full text
Article -
16
Exploring shared therapeutic targets in diabetic cardiomyopathy and diabetic foot ulcers through bioinformatics analysis
Published 2024-01-01“…For patients with DCM combined with diabetic foot ulcer (DFU), there are currently no good therapeutic targets and drugs. Here, we investigated the underlying network of molecular actions associated with the occurrence of these two complications. …”
Get full text
Article -
17
-
18
The genesis and evolution of acute myeloid leukemia stem cells in the microenvironment: From biology to therapeutic targeting
Published 2022-09-01“…Understanding the relationship between LSCs, the BMM, and the generation and evolution laws of LSCs can facilitate the development of effective therapeutic targets and increase the efficiency of LSCs elimination in AML.…”
Get full text
Article -
19
N-glycoproteomic profiling revealing novel coronavirus therapeutic targets potentially involved in Cepharanthine's intervention
Published 2022-12-01“…In conclusion, this article provides important ideas about the infection mechanism of novel coronaviruses, providing evidence for CEP as a promising therapeutic option for coronavirus infection.…”
Get full text
Article -
20