Antibody avidity to pertussis toxin after acellular pertussis vaccination and infection by Aapo Knuutila, Tine Dalby, Niina Ahvenainen, Alex-Mikael Barkoff, Charlotte Sværke Jørgensen, Kurt Fuursted, Jussi Mertsola, Qiushui He

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Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis by Aapo Knuutila, Alex-Mikael Barkoff, Jussi Mertsola, Radim Osicka, Peter Sebo, Qiushui He

“…Serological diagnosis of pertussis is mainly based on anti-pertussis toxin (PT) IgG antibodies. Since PT is included in all acellular vaccines (ACV), serological assays do not differentiate antibodies induced by ACVs and infection. …”
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Pertussis toxin neutralizing antibody response after an acellular booster vaccination in Dutch and Finnish participants of different age groups by Aapo Knuutila, Pauline Versteegen, Alex-Mikael Barkoff, Pieter van Gageldonk, Jussi Mertsola, Guy Berbers, Qiushui He

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Evaluation of Anti-PT Antibody Response after Pertussis Vaccination and Infection: The Importance of Both Quantity and Quality by Alex-Mikael Barkoff, Aapo Knuutila, Jussi Mertsola, Qiushui He

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Effect of immunization during pregnancy and pre-existing immunity on diphtheria-tetanus-acellular pertussis vaccine responses in infants by Aapo Knuutila, Alex-Mikael Barkoff, Lauri Ivaska, Elina Tenhu, Johanna Teräsjärvi, Pieter van Gageldonk, Annemarie Buisman, Jussi Mertsola, Qiushui He

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Multiplex Point-of-Care Tests for the Determination of Antibodies after Acellular Pertussis Vaccination by Aapo Knuutila, Carita Rautanen, Jussi Mertsola, Qiushui He

“…Most of the current serological diagnosis of pertussis is based on pertussis toxin (PT) IgG antibodies and does not differentiate between vaccination and infection-induced antibodies. …”
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Memory B Cell Activation Induced by Pertussis Booster Vaccination in Four Age Groups of Three Countries by Pauline Versteegen, Alex-Mikael Barkoff, Marta Valente Pinto, Jan van de Kasteele, Aapo Knuutila, Sagida Bibi, Lia de Rond, Johanna Teräsjärvi, Katherine Sanders, Mary-lène de Zeeuw-Brouwer, Raakel Luoto, Hinke ten Hulscher, Elizabeth A. Clutterbuck, Elisabeth A. M. Sanders, Elisabeth A. M. Sanders, Jussi Mertsola, Guy A. M. Berbers, Qiushui He, Dominic F. Kelly, Dominic F. Kelly, Anne-Marie Buisman, PERISCOPE Consortium

“…Memory B cells at baseline, day 28, and 1 year post-vaccination were measured by a pertussis toxin (Ptx), filamentous haemagglutinin (FHA), and pertactin (Prn) specific ELISpot assay. …”
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