Neuroimaging of tissue microstructure as a marker of neurodegeneration in the AT(N) framework: defining abnormal neurodegeneration and improving prediction of clinical status by Rigina L. Gallagher, Rebecca Langhough Koscik, Jason F. Moody, Nicholas M. Vogt, Nagesh Adluru, Steven R. Kecskemeti, Carol A. Van Hulle, Nathaniel A. Chin, Sanjay Asthana, Gwendlyn Kollmorgen, Ivonne Suridjan, Cynthia M. Carlsson, Sterling C. Johnson, Douglas C. Dean, Henrik Zetterberg, Kaj Blennow, Andrew L. Alexander, Barbara B. Bendlin

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Tau as a fluid biomarker of concussion and neurodegeneration by Iftakher Hossain, Kaj Blennow, Jussi P Posti, Henrik Zetterberg

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Blood biomarkers and neurodegeneration in individuals exposed to repetitive head impacts by Charles Bernick, Guogen Shan, Aaron Ritter, Nicholas J. Ashton, Kaj Blennow, Juan Lantero-Rodriguez, Anniina Snellman, Henrik Zetterberg

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Sex differences in CSF biomarkers for neurodegeneration and blood‐brain barrier integrity by Tobias Skillbäck, Kaj Blennow, Henrik Zetterberg, Sara Shams, Alejandra Machado, Joana Pereira, Olof Lindberg, Michelle M. Mielke, Anna Zettergren, Lina Ryden, Eric Westman, Lars‐Olof Wahlund, Ingmar Skoog, Silke Kern

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Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer’s disease by Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E. Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M. Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M. Hughes, Marc Suárez-Calvet, Thomas K. Karikari, Tormod Fladby, Kaj Blennow

“…Abstract Staging amyloid-beta (Aβ) pathophysiology according to the intensity of neurodegeneration could identify individuals at risk for cognitive decline in Alzheimer’s disease (AD). …”
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Effects of pre‐analytical procedures on blood biomarkers for Alzheimer's pathophysiology, glial activation, and neurodegeneration by Nicholas J. Ashton, Marc Suárez‐Calvet, Thomas K. Karikari, Juan Lantero‐Rodriguez, Anniina Snellman, Mathias Sauer, Joel Simrén, Carolina Minguillon, Karine Fauria, Kaj Blennow, Henrik Zetterberg

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Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological disorders by Per Kristian Eide, Aslan Lashkarivand, Are Pripp, Lars Magnus Valnes, Markus Herberg Hovd, Geir Ringstad, Kaj Blennow, Henrik Zetterberg

“…Abstract Clearance of neurotoxic brain proteins via cerebrospinal fluid (CSF) to blood has recently emerged to be crucial, and plasma biomarkers of neurodegeneration were newly introduced to predict neurological disease. …”
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Biomarkers for neurodegeneration impact cognitive function: a longitudinal 1-year case–control study of patients with bipolar disorder and healthy control individuals by Ulla Knorr, Anja Hviid Simonsen, Henrik Zetterberg, Kaj Blennow, Mira Willkan, Julie Forman, Kamilla Miskowiak, Steen Gregers Hasselbalch, Lars Vedel Kessing

“…The study aimed to investigate the association between these biomarkers indicative of Alzheimer’s disease and those reflecting neurodegeneration alongside their impact on cognitive function in patients with BD and healthy control individuals (HC). …”
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Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer’s disease and neurodegeneration stratified by sex by Irene Cumplido-Mayoral, Marina García-Prat, Grégory Operto, Carles Falcon, Mahnaz Shekari, Raffaele Cacciaglia, Marta Milà-Alomà, Luigi Lorenzini, Silvia Ingala, Alle Meije Wink, Henk JMM Mutsaerts, Carolina Minguillón, Karine Fauria, José Luis Molinuevo, Sven Haller, Gael Chetelat, Adam Waldman, Adam J Schwarz, Frederik Barkhof, Ivonne Suridjan, Gwendlyn Kollmorgen, Anna Bayfield, Henrik Zetterberg, Kaj Blennow, Marc Suárez-Calvet, Verónica Vilaplana, Juan Domingo Gispert, ALFA study, EPAD study, ADNI study, OASIS study

“…Brain-age delta was positively associated with plasma neurofilament light, a marker of neurodegeneration, and sex differences in the brain effects of this marker were found. …”
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Neurogranin and Neurofilament Light Chain as Preclinical Biomarkers in Scrapie by Marina Betancor, Sonia Pérez-Lázaro, Alicia Otero, Belén Marín, Inmaculada Martín-Burriel, Kaj Blennow, Juan José Badiola, Henrik Zetterberg, Rosa Bolea

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Plasma neurofilament light chain in memory clinic practice: Evidence from a real-life study by Karl Götze, Agathe Vrillon, Elodie Bouaziz-Amar, François Mouton-Liger, Jacques Hugon, Matthieu Martinet, Julien Dumurgier, Emmanuel Cognat, Henrik Zetterberg, Kaj Blennow, Claire Hourrègue, Claire Paquet, Matthieu Lilamand

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Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older adults by Michael Malek-Ahmadi, Yi Su, Valentina Ghisays, Ji Luo, Vivek Devadas, Yinghua Chen, Wendy Lee, Hillary Protas, Kewei Chen, Henrik Zetterberg, Kaj Blennow, Richard J. Caselli, Eric M. Reiman

“…Abstract Background Plasma neurofilament light (NfL) is an indicator of neurodegeneration and/or neuroaxonal injury in persons with Alzheimer’s disease (AD) and a wide range of other neurological disorders. …”
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Association between ventricular CSF biomarkers and outcome after shunt surgery in idiopathic normal pressure hydrocephalus by Rebecca Grønning, Anna Jeppsson, Per Hellström, Katarina Laurell, Dan Farahmand, Henrik Zetterberg, Kaj Blennow, Carsten Wikkelsø, Mats Tullberg

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Identifying clinically useful biomarkers in neurodegenerative disease through a collaborative approach: the NeuroToolKit by Sterling C. Johnson, Marc Suárez-Calvet, Ivonne Suridjan, Carolina Minguillón, Juan Domingo Gispert, Erin Jonaitis, Agata Michna, Margherita Carboni, Tobias Bittner, Christina Rabe, Gwendlyn Kollmorgen, Henrik Zetterberg, Kaj Blennow

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Insulin resistance is related to cognitive decline but not change in CSF biomarkers of Alzheimer's disease in non‐demented adults by Gilda E. Ennis, Rebecca L. Koscik, Yue Ma, Erin M. Jonaitis, Carol A. Van Hulle, Tobey J. Betthauser, Allison M. Randall, Nathaniel Chin, Corinne D. Engelman, Rozalyn Anderson, Ivonne Suridjan, Gwendlyn Kollmorgen, Bradley T. Christian, Cynthia M. Carlsson, Sanjay Asthana, Sterling C. Johnson, Henrik Zetterberg, Kaj Blennow, Barbara B. Bendlin

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Obinutuzumab-Induced B Cell Depletion Reduces Spinal Cord Pathology in a CD20 Double Transgenic Mouse Model of Multiple Sclerosis by Thomas Breakell, Sabine Tacke, Verena Schropp, Henrik Zetterberg, Kaj Blennow, Eduard Urich, Stefanie Kuerten

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Inflammatory biomarkers for neurobehavioral dysregulation in former American football players: findings from the DIAGNOSE CTE Research Project by Suzan van Amerongen, Surya V. Pulukuri, Fatima Tuz-Zahra, Yorghos Tripodis, Jonathan D. Cherry, Charles Bernick, Yonas E. Geda, Jennifer V. Wethe, Douglas I. Katz, Michael L. Alosco, Charles H. Adler, Laura J. Balcer, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Daniel H. Daneshvar, Elizabeth A. Colasurdo, Jeffrey J. Iliff, Gail Li, Elaine R. Peskind, Martha E. Shenton, Eric M. Reiman, Jeffrey L. Cummings, Robert A. Stern, for the DIAGNOSE CTE Research Project Investigators

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A phase 1b randomized clinical trial of CT1812 to measure Aβ oligomer displacement in Alzheimer’s disease using an indwelling CSF catheter by Kelsie M. LaBarbera, Yvette I. Sheline, Nicholas J. Izzo, Carla M. Yuede, Lora Waybright, Raymond Yurko, Hannah M. Edwards, Woodrow D. Gardiner, Kaj Blennow, Henrik Zetterberg, Anne Börjesson-Hanson, Roger Morgan, Charles S. Davis, Robert J. Guttendorf, Lon S. Schneider, Steven DeKosky, Harry LeVine, Michael Grundman, Anthony O. Caggiano, John R. Cirrito, Susan M. Catalano, Mary E. Hamby

“…Translational Neurodegeneration…”
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Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer’s Disease by Juan Lantero-Rodriguez, Gemma Salvadó, Anniina Snellman, Laia Montoliu-Gaya, Wagner S. Brum, Andrea L. Benedet, Niklas Mattsson-Carlgren, Pontus Tideman, Shorena Janelidze, Sebastian Palmqvist, Erik Stomrud, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Oskar Hansson

“…Molecular Neurodegeneration…”
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Tracking reactive astrogliosis in autosomal dominant and sporadic Alzheimer’s disease with multi-modal PET and plasma GFAP by Konstantinos Chiotis, Charlotte Johansson, Elena Rodriguez-Vieitez, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Caroline Graff, Agneta Nordberg

“…Molecular Neurodegeneration…”
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