NK cell phenotypic profile during active TB in people living with HIV-evolution during TB treatment and implications for bacterial clearance and disease severity by Thando Glory Maseko, Santhuri Rambaran, Slindile Ngubane, Lara Lewis, Sinaye Ngcapu, Razia Hassan-Moosa, Derseree Archary, Rubeshan Perumal, Nesri Padayatchi, Kogieleum Naidoo, Aida Sivro

“…Here, we utilized peripheral blood specimens from the Improving Retreatment Success CAPRISA 011 study to characterize NK cell phenotypes during active TB in individuals with or without HIV co-infection. …”
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Field evaluations of four SARS-CoV-2 rapid antigen tests during SARS-CoV-2 Delta variant wave in South Africa by Natasha Samsunder, Gila Lustig, Slindile Ngubane, Thando Glory Maseko, Santhuri Rambaran, Sinaye Ngcapu, Stanley Nzuzo Magini, Lara Lewis, Cherie Cawood, Ayesha B. M. Kharsany, Quarraisha Abdool Karim, Salim Abdool Karim, Kogieleum Naidoo, Aida Sivro

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Higher plasma interleukin − 6 levels are associated with lung cavitation in drug-resistant tuberculosis by Thando Glory Maseko, Slindile Ngubane, Marothi Letsoalo, Santhuri Rambaran, Derseree Archary, Natasha Samsunder, Rubeshan Perumal, Surie Chinappa, Nesri Padayatchi, Kogieleum Naidoo, Aida Sivro

“…Methods Plasma samples were obtained from 128 participants from the CAPRISA 020 Individualized M(X)drug-resistant TB Treatment Strategy Study (InDEX) prior to treatment initiation. …”
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Blood monocyte and dendritic cell profiles among people living with HIV with Mycobacterium tuberculosis co-infection by Santhuri Rambaran, Thando Glory Maseko, Lara Lewis, Razia Hassan-Moosa, Derseree Archary, Sinaye Ngcapu, Nigel Garrett, Lyle R. McKinnon, Nesri Padayatchi, Kogieleum Naidoo, Aida Sivro

“…Using flow cytometry, we characterized the frequencies and phenotypic differences in monocytes and dendritic cell populations using peripheral blood mononuclear cells from individuals with recurrent, active pulmonary tuberculosis with and without coexisting HIV infection (CAPRISA 011, Clinicaltrials.gov, NCT02114684, 29/01/2014) and compared them to samples from HIV positive individuals and healthy controls. …”
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Isoniazid resistance-conferring mutations are associated with highly variable phenotypic resistance by Senamile Lale Ngema, Navisha Dookie, Rubeshan Perumal, Louansha Nandlal, Nikita Naicker, Marothi Peter Letsoalo, Max O'Donnell, Azraa Khan, Nesri Padayatchi, Kogieleum Naidoo

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Adaptive evaluation of mHealth and conventional adherence support interventions to optimize outcomes with new treatment regimens for drug-resistant tuberculosis and HIV in South Af... by Jesse Ross, Rubeshan Perumal, Allison Wolf, Mbali Zulu, Kevin Guzman, Boitumelo Seepamore, Karl Reis, Hlengiwe Nyilana, Senzo Hlathi, Radhamoney Narasimmulu, Ying Kuen K. Cheung, K. Rivet Amico, Gerald Friedland, Amrita Daftary, Jennifer R. Zelnick, Kogieleum Naidoo, Max R. O’Donnell

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Biological mechanisms underpinning the development of long COVID by Rubeshan Perumal, Letitia Shunmugam, Kogieleum Naidoo, Dave Wilkins, Alfredo Garzino-Demo, Christian Brechot, Anders Vahlne, Janko Nikolich

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Application of Next Generation Sequencing for Diagnosis and Clinical Management of Drug-Resistant Tuberculosis: Updates on Recent Developments in the Field by Navisha Dookie, Azraa Khan, Nesri Padayatchi, Nesri Padayatchi, Kogieleum Naidoo, Kogieleum Naidoo

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Long COVID: a review and proposed visualization of the complexity of long COVID by Rubeshan Perumal, Rubeshan Perumal, Rubeshan Perumal, Letitia Shunmugam, Kogieleum Naidoo, Salim S. Abdool Karim, Dave Wilkins, Dave Wilkins, Alfredo Garzino-Demo, Alfredo Garzino-Demo, Christian Brechot, Sairam Parthasarathy, Anders Vahlne, Anders Vahlne, Janko Ž. Nikolich, Janko Ž. Nikolich, Janko Ž. Nikolich

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Detection of differentially culturable tubercle bacteria in sputum from drug-resistant tuberculosis patients by Bhavna G. Gordhan, Astika Sewcharran, Marothi Letsoalo, Thilgavathy Chinappa, Nonhlanhla Yende-Zuma, Nonhlanhla Yende-Zuma, Nesri Padayatchi, Nesri Padayatchi, Kogieleum Naidoo, Kogieleum Naidoo, Bavesh D. Kana

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Rapid Diagnosis of Drug-Resistant Tuberculosis–Opportunities and Challenges by Kogieleum Naidoo, Rubeshan Perumal, Senamile L. Ngema, Letitia Shunmugam, Anou M. Somboro

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A cluster‐randomized controlled trial to improve the quality of integrated HIV‐tuberculosis services in primary healthcareclinics in South Africa by Santhanalakshmi Gengiah, Pierre M. Barker, Nonhlanhla Yende‐Zuma, Mduduzi Mbatha, Shane Naidoo, Myra Taylor, Marian Loveday, Mesuli Mhlongo, Clark Jackson, Andrew J. Nunn, Nesri Padayatchi, Salim S. Abdool Karim, Kogieleum Naidoo

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The impact of enteral feeding and therapeutic monitoring of rifampicin with dose escalation in critically ill patients with tuberculosis by Rubeshan Perumal, Kogieleum Naidoo, Anushka Naidoo, Marothi P. Letsoalo, Aliasgar Esmail, Ivan Joubert, Paolo Denti, Lubbe Wiesner, Nesri Padayatchi, Gary Maartens, Keertan Dheda

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Affordable drug resistance genotyping of HIV-1 reverse transcriptase, protease and integrase genes, for resource limited settings by Sontaga Manyana, Melendhran Pillay, Lilishia Gounder, Aabida Khan, Pravi Moodley, Kogieleum Naidoo, Benjamin Chimukangara

“…Methods We obtained remnant plasma samples from CAPRISA 103 study and amplified HIV-1 PR, RT and IN genes, using an innovative PCR assay. …”
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Polymorphisms within the SARS-CoV-2 Human Receptor Genes Associate with Variable Disease Outcomes across Ethnicities by Theolan Adimulam, Thilona Arumugam, Anushka Naidoo, Kogieleum Naidoo, Veron Ramsuran

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HIV-1 Drug Resistance Genotyping in Resource Limited Settings: Current and Future Perspectives in Sequencing Technologies by Sontaga Manyana, Lilishia Gounder, Melendhran Pillay, Justen Manasa, Kogieleum Naidoo, Benjamin Chimukangara

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Evaluation of a transcriptomic signature of tuberculosis risk in combination with an interferon gamma release assay: A diagnostic test accuracy study by Humphrey Mulenga, Andrew Fiore-Gartland, Simon C. Mendelsohn, Adam Penn-Nicholson, Stanley Kimbung Mbandi, Elisa Nemes, Bhavesh Borate, Munyaradzi Musvosvi, Michèle Tameris, Gerhard Walzl, Kogieleum Naidoo, Gavin Churchyard, Thomas J. Scriba, Mark Hatherill

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Effect of the relationship between anaemia and systemic inflammation on the risk of incident tuberculosis and death in people with advanced HIV: a sub-analysis of the REMEMBER tria... by Mariana Araújo-Pereira, Sonya Krishnan, Padmini Salgame, Yukari C. Manabe, Mina C. Hosseinipour, Gregory Bisson, Damocles Patrice Severe, Vanessa Rouzier, Samantha Leong, Vidya Mave, Fredrick Kipyego Sawe, Abraham M. Siika, Cecilia Kanyama, Sufia S. Dadabhai, Javier R. Lama, Javier Valencia-Huamani, Sharlaa Badal-Faesen, Umesh Gangaram Lalloo, Kogieleum Naidoo, Lerato Mohapi, Cissy Kityo, Bruno B. Andrade, Amita Gupta

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A systematic review of risk factors for mortality among tuberculosis patients in South Africa by Tamaryn J Nicholson, Graeme Hoddinott, James A Seddon, Mareli M Claassens, Marieke M van der Zalm, Elisa Lopez, Peter Bock, Judy Caldwell, Dawood Da Costa, Celeste de Vaal, Rory Dunbar, Karen Du Preez, Anneke C Hesseling, Kay Joseph, Ebrahim Kriel, Marian Loveday, Florian M Marx, Sue-Ann Meehan, Susan Purchase, Kogieleum Naidoo, Lenny Naidoo, Fadelah Solomon-Da Costa, Rosa Sloot, Muhammad Osman

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