Pre-operative flow mediated dilatation in patients undergoing coronary artery bypass surgery: Prediction of NO-bioavailability and vascular superoxide production in arterial and vein grafts by Antoniades, C, Mussa, S, Shirodaria, C, Lee, J, Van-Assche, T, Diesch, J, Taggart, D, Channon, K, Leeson, P

Relation of preoperative radial artery flow-mediated dilatation to nitric oxide bioavailability in radial artery grafts used in off-pump coronary artery bypass grafting. by Antoniades, C, Mussa, S, Shirodaria, C, Lee, J, Diesch, J, Taggart, D, Channon, K, Leeson, P

“…The radial artery is prone to vasospasm after coronary bypass surgery, and endothelial dysfunction is likely to be a key factor. …”

Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis. by Antoniades, C, Cunnington, C, Antonopoulos, A, Neville, M, Margaritis, M, Demosthenous, M, Bendall, J, Hale, A, Cerrato, R, Tousoulis, D, Bakogiannis, C, Marinou, K, Toutouza, M, Vlachopoulos, C, Leeson, P, Stefanadis, C, Karpe, F, Channon, K

“…In Study 4, vessel segments from 19 patients undergoing coronary bypass surgery were incubated with or without cytokines (interleukin-6/tumor necrosis factor-α/lipopolysaccharide) for 24 hours. …”

Preoperative sCD40L levels predict risk of atrial fibrillation after off-pump coronary artery bypass graft surgery. by Antoniades, C, Van-Assche, T, Shirodaria, C, Diesch, J, Antonopoulos, A, Lee, J, Cunnington, C, Tousoulis, D, Stefanadis, C, Casadei, B, Taggart, D, Channon, K, Leeson, P

“…BACKGROUND: The risk of atrial fibrillation (AF) after coronary bypass surgery has been related to redox state, inflammation, and ischemia. …”

Induction of vascular GTP-cyclohydrolase i and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis by Antoniades, C, Cunnington, C, Antonopoulos, A, Neville, M, Margaritis, M, Demosthenous, M, Bendall, J, Hale, A, Cerrato, R, Tousoulis, D, Bakogiannis, C, Marinou, K, Toutouza, M, Vlachopoulos, C, Leeson, P, Stefanadis, C, Karpe, F, Channon, K

“…In Study 4, vessel segments from 19 patients undergoing coronary bypass surgery were incubated with or without cytokines (interleukin-6/tumor necrosis factor-α/lipopolysaccharide) for 24 hours. …”

Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endotheli... by Antoniades, C, Shirodaria, C, Leeson, P, Antonopoulos, A, Warrick, N, Van-Assche, T, Cunnington, C, Tousoulis, D, Pillai, R, Ratnatunga, C, Stefanadis, C, Channon, K

“…METHODS AND RESULTS: Paired samples of saphenous veins (SVs) and internal mammary arteries (IMAs) were collected from 201 patients undergoing coronary bypass surgery, and serum ADMA was measured pre-operatively. …”