STUB1-mediated ubiquitination regulates the stability of GLUD1 in lung adenocarcinoma by Qifan Hu, Jiapeng Lei, Zhujun Cheng, Jing Xu, Lei Wang, Yi Yuan, Mingxi Gan, Yanan Wang, Yilin Xie, Lu Yao, Keru Wang, Yuhan Liu, Wenze Xun, Jian-Bin Wang, Tianyu Han

“…We discovered that GLUD1 showed a high protein expression in lung adenocarcinoma cells or tissues. …”
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In Vitro and In Vivo Photoprotective Effects of (-)-Loliode Isolated from the Brown Seaweed, <i>Sargassum horneri</i> by Lei Wang, Hyun-Soo Kim, Jun-Geon Je, Xiaoting Fu, Caoxing Huang, Ginnae Ahn, Jae-Young Oh, K. K. Asanka Sanjeewa, Jiachao Xu, Xin Gao, In-Kyu Yeo, You-Jin Jeon

“…The compound, (-)-loliode, isolated from the brown seaweed <i>Sargassum horneri</i>, showed strong antioxidant and anti-inflammatory activities in in vitro and in vivo models. …”
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Molecular Mechanism Analysis of STIM1 Thermal Sensation by Xiaoling Liu, Tianyuan Zheng, Yan Jiang, Lei Wang, Yuchen Zhang, Qiyu Liang, Yuejie Chen

“…Furthermore, both the TM and SOAR domains exhibited similarities and differences between STIM1–mediated thermal sensation and store–operated calcium entry (SOCE), and the key sites of Orai1 showed similar roles in these two responses. Additionally, the TM23 (comprising TM2, loop2, and TM3) region of Orai1 was identified as the key domain determining the STIM1/Orai1 thermal response pattern, while the temperature reactive mode of STIM1/Orai3 seemed to result from a combined effect of Orai3. …”
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A retrospective analysis based on multiple machine learning models to predict lymph node metastasis in early gastric cancer by Tao Yang, Tao Yang, Javier Martinez-Useros, Javier Martinez-Useros, JingWen Liu, Isaias Alarcón, Chao Li, WeiYao Li, WeiYao Li, Yuanxun Xiao, Xiang Ji, YanDong Zhao, Lei Wang, Salvador Morales-Conde, Zuli Yang

“…Interestingly, all prediction models of cohort I showed accuracy between 70 and 81%. Furthermore, the prediction models of the cohort II exhibited accuracy between 48 and 82%. …”
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Prenatal Diagnosis of Isovaleric Acidemia From Amniotic Fluid Using Genetic and Biochemical Approaches by Si Ding, Lili Liang, Wenjuan Qiu, Huiwen Zhang, Bing Xiao, Liping Dong, Wenjun Ji, Feng Xu, Zhuwen Gong, Xuefan Gu, Lei Wang, Lianshu Han

“…The remaining six fetuses were determined to be unaffected based on a normal AF metabolite profile, except one showed slightly elevated C5 and they were found to be carriers according to genetic analysis. …”
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POU class 2 homeobox associating factor 1 (POU2AF1) participates in abdominal aortic aneurysm enlargement based on integrated bioinformatics analysis by Jinze Meng, Hao Wen, Xintong Li, Boyang Luan, Shiqiang Gong, Jie Wen, Yifei Wang, Lei Wang

“…In addition, by using GSE7084 and GSE98278 for verification, POU2AF1 showed potential diagnostic value between AAA and normal groups, and exhibited a significant higher expression level in large AAA samples compared with small AAA samples. …”
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Synthesis and Antibacterial Evaluation of <i>N</i>-phenylacetamide Derivatives Containing 4-Arylthiazole Moieties by Hui Lu, Xia Zhou, Lei Wang, Linhong Jin

“…<i>Citri</i> (<i>Xac</i>) and <i>X.oryzae</i> pv<i>. oryzicola</i> (<i>Xoc</i>)—showing promising results. The minimum 50% effective concentration (EC₅₀) value of <i>N-</i>(4-((4-(4-fluoro-phenyl)thiazol-2-yl)amino)phenyl)acetamide (<b>A</b>₁) is 156.7 µM, which is superior to bismerthiazol (230.5 µM) and thiodiazole copper (545.2 µM). …”
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Distribution Law of In Situ Stress and Its Engineering Application in Rock Burst Control in Juye Mining Area by Guangchao Zhang, You Li, Xiangjun Meng, Guangzhe Tao, Lei Wang, Hanqing Guo, Chuanqi Zhu, Hao Zuo, Zhi Qu

“…The main conclusions included: (1) There are two types of in-situ stress states in the Juye mining area, <i>σ_H > σ_V > σ_h</i> (42.42%) and <i>σ_H > σ_h > σ_V</i> (57.57%), which are mainly caused by the tectonic stress of the Heze and Fushan faults (The <i>σ_H, σ_V, and σ_h</i> is the maximum principal stress, vertical principal stress or intermediate principal stress and minimum principal stress respectively). (2) The lateral pressure coefficients <i>K_H</i>, <i>K_h</i>, and <i>K_av</i> show a non-linear distribution with increased depth, approaching 1.32, 0.96, and 1.41, respectively. …”
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Combination therapy with bevacizumab and a CCR2 inhibitor for human ovarian cancer: An in vivo validation study by Tianyue Zhai, Takashi Mitamura, Lei Wang, Shimpei I. Kubota, Masaaki Murakami, Shinya Tanaka, Hidemichi Watari

“…Conclusions BEV/CCR2i showed a sustained anticancer immunity‐independent effect in human ovarian cancer that was more significant in serous carcinoma than in clear cell carcinoma.…”
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